ACE hanawa - inganci da kwayoyi na zamani cardiology

Hanawa ko ACE angiotensin tana mayar factor kira m vasodilators amfani a cardiology domin lura da hauhawar jini. A mataki na wannan kungiyar da kwayoyi da aka yi tsawo tarewa adrenal hormone angiotensin II - pressor babban factor shafi cikin jini darajar. ACE hanawa hana rugujewar bradykinin, wanda kuma rinjayar da yanayin tasoshi, ya kuma inganta a kan tsawo daga cikin jini. Wadannan kwayoyi taimaka wajen kara da jini matakan vasodilator prostaglandins rage bayyanar cututtuka na kullum zuciya maye, sukan lura a marasa lafiya da muhimmanci hauhawar jini. A lokaci guda, ACE hanawa, sabanin sauran kwayoyi da runtse jini da wani sakamako a kan glucose da kuma sia metabolism, rage urinary gina jiki kodan.

ACE hanawa ana amfani da fiye da shekaru 40. A farko na wannan kungiya da kwayoyi a shekarar 1975 aka hada captopril, amfani a yau. A 'yan shekarun baya ya samu enalapril da lisinopril. Su aka maye gurbinsu da more zamani ACE hanawa da wani sabon ƙarni.

A zamani cardiology ACE hanawa ake amfani da matsayin babban kwayoyi domin lura da hawan jinni cuta, ischemic cututtukan zuciya, na kullum zuciya maye.

ACE hanawa rarrabuwa

Akwai da dama sukayi fassara da ACE hanawa, wadda ake bisa kan hanyar kau da kwayoyi daga jiki, dangane da sinadaran kungiyar a cikin kwayoyin hulda da ACE cibiyar na aiki matakai. Mafi na kowa rarrabuwa da pharmacological mataki.

Bisa ga pharmacological mataki na angiotensin tana mayar hanawa duk abubuwan kasu kashi uku kungiyoyin.

Na farko da kungiyar ne captopril ko kaho, wanda kai tsaye damuarn, Ina nufin damuarn da angiotensin na mayar aiki na hormone a wani m lokaci - angiotensin II. Don kula captopril ko kapoten al'ada jini dauka uku zuwa sau hudu a rana.

Don na biyu kungiyar ne enalapril, ramipril, trandalopril, tsilazipril, fosinopril, quinapril da sauran kwayoyi da cewa ana tuba a cikin jiki a cikin aiki mahadi da cewa suna da wani vasodilatory sakamako. Wadannan kwayoyi su ne isa zuwa sama ne kawai sau daya a rana.

A karshe, na uku kungiyar kunshi lisinopril Zestril, prinivil, prestarium ko perindopril. ACE hanawa ne na uku kungiyar bada shawarar a yi sau daya ko biyu a lokacin da rana.

Side effects na ACE hanawa

Lokacin da ka karɓi wannan rukuni na kwayoyi ya zama sane da yiwu ci gaban illa. A wasu lokuta, shan ACE hanawa iya bayyana bushe tari, ta ƙara potassium matakai a cikin jini, juwa ko jiri, rashin lafiyan fata rash, angioedema. Wadannan rikitarwa suna gaba daya shafe bayan miyagun ƙwayoyi janye. Dry tari bayyana a cikin na uku-rana ta biyar magani. Its bayyanar shi ne saboda da jari a cikin huhu na bradykinin. Tari vuya gaba daya bayan an daina hanawa. Wasu marasa lafiya zai iya rage ci da kuma gaji da damuwa da dandano ji.

Daya daga cikin manyan contraindications ga yin amfani da ACE hanawa ne dangantakar koda jijiya constriction. A wannan yanayin, da jini ne ya karu da kiwon da matakin na renin a cikin jini zuwa da wadannan kwayoyi da wani sakamako.

Special kula ya kamata a ba ACE hanawa a kullum hanta da koda cututtuka ga ci gaban bayyanar cututtuka na hanta da koda insufficiency.