Analogs "Ksarelto": price, umarnin don amfani da

Daya daga cikin kwayoyi, wanda nasa ne da pharmacological kungiyar na anticoagulant jamiái, da miyagun ƙwayoyi ne "Ksarelto". Wannan magani damuarn factor Xa, kuma shi, bi da bi, wani bangaren na prothrombin activator da kuma daya daga cikin aka gyara bayar dace jini coagulation (irin kaddarorin da kuma analogues "Ksarelto").

Yau da za'ayi yawa banza yunkurin janye da miyagun ƙwayoyi, wanda zai yi irin wannan sakamako, kuma ta haka ne don samar da wani m na illa. Bayan mahara lokaci-cinyewa kokarin da ya cancanci takwaransa - da miyagun ƙwayoyi "Pradaksa". Da miyagun ƙwayoyi - kawai canza cewa cikakken za a iya amfani maimakon "Ksarelto" shirye-shiryen. Its halaye ne kusan m zuwa sama, kadai bambanci - da aiki sashi ciki, wanda a da shirye-shirye ne rivaroxaban.

pharmacodynamics

All analogues "Ksarelto" da irin wannan sakamako. Abinda suka sãɓã wa jũna - da yawa da kuma gwajin kwari nuna alama na illa. The kawai ya cancanci analogue da miyagun ƙwayoyi, wanda yana da irin wannan sakamako ga shi, shi ne wani magani "Pradaksa".

Wannan magani da kuma ta Rasha kwatankwacin "Ksarelto" su ne kai tsaye sosai zabe kwayoyi da hana mataki na Factor Xa, watau hana shi. Wannan magani yana da babban baka bioavailability, duk da haka enteral hanya na gwamnati ne tsakiyar zuwa gare shi.

Jamhuriyar rawa a cikin cascade na coagulation factor X kunnawa taka m biotransformation factor Xa via ciki da waje coagulation hanya.

shaidar

Yawanci, analogs "Ksarelto" da kuma shirye-shiryen da kanta da ake amfani a cikin wadannan yanayi:

• Yin rigakafi da prophylaxis bugun jini.
• Yin rigakafi da taimako na tsari embolism.
  
  (A irin haka ne, medicament aka nuna a marasa lafiya tare da atrial fibrillation, wanda shi ne maras valvular asalin.)

• Cire ko rigakafin plugging na zurfin jannayẽnsa thrombi.
• Rigakafin komawa da na huhu embolism.

Drug "Pradaksa", wanda yake shi ne irin wannan, an kuma nuna ga rigakafin venous thromboembolic events in marasa lafiya da suke yi halartar tiyata don maye gurbin daya daga cikin gidajen abinci na ƙananan wata gabar jiki.

contraindications

Duk wani Rasha m "Ksarelto" yana da wadannan contraindications (za su iya zama daban-daban, amma kawai don a kananan har):

• ýan ko hadarin manifestations na rashin lafiyan halayen ga abubuwa dauke a cikin medicament.
• aiki na jini wanda da nauyi informativeness da na asibiti jarrabawa (msl, intracavitary zub da jini, ko hemorrhage a cikin kwakwalwa).

• a halin da ake ciki, a cikinsa akwai wani ƙãra hadarin zub da jini girma, msl, a aiki miki matakai a cikin gastrointestinal fili.
• miyagun ƙwayoyi far jamiái wanda mallaka irin wannan Properties - hana coagulation.
• ta amfani da unfractionated heparin a kashi zama dole ga m aiki na catheter.
• daban-daban hanta cututtuka, da ci gaban wanda zai iya sa zub da jini na daban-daban etiology.
• duk abin da takwarorinsu "Ksarelto" ana contraindicated a marasa lafiya tare da koda insufficiency, abin da ke faruwa a kowane lokaci.
• lactose rashin ha} uri, kasa abun ciki na galactose a jiki;
• ciki da kuma lactation.
• kuma a kan miyagun ƙwayoyi da kuma daban-daban analogs "Ksarelto" akwai wani zamani iyaka 18+.

Category na mutane da suke iya kai wannan magani tare da taka tsantsan da kuma karkashin kulawa da wani gwani

Tare da taka tsantsan da kuma karkashin kulawa na likita bada shawarar yin amfani da "Ksarelto" umarnin don amfani (as analogues) a cikin wadannan lokuta:

• bi da marasa lafiya da suke da wani ƙãra hadarin zub da jini a cikin samuwar.
• kwanan canjawa wuri ulcerative cutar ciwon predisposition komawa.
• magani na koda gazawar da sãɓãwar launukansa digiri a hade tare da kwayoyi da kara rivaroxaban abun ciki a cikin jiki na haƙuri.
• Marasa lafiya jurewa far kwayoyi iya inganta hemostasis.
• shirye-shirye da suke iya kara matakin rivaroxaban, msl, antifungal kwayoyi azole kungiyar.
• da miyagun ƙwayoyi da kuma analogue Allunan "Ksarelto" An contraindicated a marasa lafiya tare da HIV, idan sun kawai ya dauki wani iri-iri protease hanawa da cutar.

Shan a lokacin daukar ciki da kuma nono

Don kwanan wata, an ba daidai m, kamar yadda rinjayar "Ksarelto" analogues da miyagun ƙwayoyi a kan inganci da kuma aminci a mata masu juna biyu.

Gwaje-gwaje da aka gudanar a ranar dakin gwaje-gwaje dabbobi sun nuna furta yawan guba na aiki abu da shirye-shiryen a kan kwayoyin expectant uwa, kamar yadda da miyagun ƙwayoyi sa mai tsanani haihuwa yawan guba na mace jiki.

A cewar dakin gwaje-gwaje sakamakon binciken, da miyagun ƙwayoyi "Ksarelto" analogue da yake kama da su pharmacological mataki suna da ikon ƙetare Mahaifa, don haka da miyagun ƙwayoyi ne contraindicated.

Har ila yau, a lokacin da aikace-aikace na "Ksarelto" bai kamata mata su manta game da tasiri matakan da maganin hana haihuwa, tun ganewa, wanda ke tafiya tare da musayar kudi da miyagun ƙwayoyi, za a iya barnatar da shafi fetal ci gaba.

Makasudin farillai game da sakamako daga cikin miyagun ƙwayoyi amfani a cikin lactation lokaci, a wannan lokacin ba ya wanzu, amma dakin gwaje-gwaje karatu a dakin gwaje-gwaje dabbobi bayar da shawarar cewa aiki abu - rivaroxaban - yana da ikon metabolize kuma ba excreted a nono. Saboda haka, shayarwa kamata rabuwa da amfani da miyagun ƙwayoyi.

Bisa ga bayanan bayar da dakin gwaje-gwaje karatu, za mu iya ce cewa rivaroxaban ba zai tasiri da ikon da wani jima'i balagagge kwayoyin don ƙirƙirar mai yiwuwa zuriyarsu a berayen, amma a cikin mutane da wannan irin gwaje-gwajen da aka gudanar.

Metabolism da kuma kawar hanya

Domin enteral liyafar akwai hanyoyi uku da kiwo, wanda ya dace da daya bisa uku na jimlar yawan wadanda ba metabolized miyagun ƙwayoyi:

• urinary tukar tumbi.
• tukar tumbi a cikin tumbi.
• kawar via koda tukar tumbi line (a wannan yanayin, kusan babu wani abu metabolized da kuma shafe a unmodified form).

Biotransformation rivaroksaba yi da sunadaran da suke zaman kanta da cytochrome tsarin.

Babban hanya - da hadawan abu da iskar shaka na wani morpholino kungiyar da kuma fadada daga cikin amide shaidu da ruwa.

Nazarin gudanar a vitro, za a iya yin hukunci da cewa rivaroxaban ne dalilin P-glycoprotein kuma mai gina jiki da samar da juriya oncological nono cuta.

Yawanci, kau na metabolites ne da za'ayi a lokacin 5-9 hours.

illa

Ya ce shirye-shiryen umarnin don amfani: analogues "Ksarelto" ko kai magani ya kamata a dauka kawai a kan takardar sayen magani. A umurci kanta ya bayyana a cikin daki-daki, da sashi daga cikin miyagun ƙwayoyi, ko ta analogues. Tabbata a karanta wa'azi liyafar!

Kasa nuna duk maras so matakai da kuma halayen wanda ya miyagun ƙwayoyi "Ksarelto" analogs. Price kwayoyi - daga 900 rubles. Shi ne m idan ka yi la'akari da cewa mafi yawan illa ne aka ware da mulki.

• Side effects cewa an lura lokacin da gwajin jini da lymphatic tsarin, suna anemia da kuma thrombocythemia, wanda ya bayyana infrequently.
• Tachycardia - kadai m dauki a lokacin da shan wannan magani.
• Zubar jinni.

Wadannan su ne da maki contraindications da miyagun ƙwayoyi "Ksarelto" wa'azi da shi.

Analogs wannan magani zai iya haifar da wani matsalar aiki na samfur na narkewa kamar fili: zub da jini, sarrafa zafi, dyspeptic bayyanar cututtuka, wani lokacin - bushe baki.

Saboda gabatarwar rivaroxaban gida halayen iya faruwa: zazzabi, kumburi a allura site lokacin gudanar parenterally hanya, wani rauni da malaise.

Ana zargin wadannan matakai taimakawa wajen shirye-shiryen "Ksarelto" takwarorinsu. A farashin da miyagun ƙwayoyi, a matsayin mai mulkin, shi ne misali a duk kantin sarƙoƙi.

Hanyar Amfani da Sashi

Cikakken bayani game da daidai liyafar iya samar da miyagun ƙwayoyi ko dai gaba daya "Ksarelto" wa'azi da shi. Analogues da miyagun ƙwayoyi a cikin wannan girmamawa ba ta sha bamban.

Wannan magani ne samuwa a kwamfutar hannu tsari, don haka kwaya ne riƙi enterally. Idan haƙuri saboda wasu dalilai ba zai iya hadiye da kwamfutar hannu - shi za a iya kasa da kuma gauraye da wani m ruwa (shayi, ruwa).

Bayan samun wannan magani ya kamata nan da nan bi abinci.

yawan abin sama

Gaza bada hašin kai norms liyafar "Ksarelto" yiwu yawan abin sama, wanda ake kullum bi symptomatically, a matsayin magani yana da wani takamaiman maganin guba.

Domin rage adsorption da miyagun ƙwayoyi a cikin kananan hanji iya zama wani sorbent, kamar kunna carbon. Har ila yau, don hanzarta tukar tumbi da metabolites zama dole don samar da tilasta diuresis, wanda yana da za'ayi via yin amfani da manyan yawa na ruwa da kuma yin amfani da diuretics.

farashin

Dangane da manufacturer, Farashin ne "Ksarelto" miyagun ƙwayoyi dabam daga 899,00 rubles. 10 Allunan, wanda dauke da 10 MG na aiki sashi, to 1740,49 Rub.

Kunshin, a cikin abin da 30 katsin, za a iya saya don 3300,00 rubles.

The most kunshin ƙunshi 100 capsules, koda halin kaka 8600 rubles.

Farashin Policy "Pradaksa" miyagun ƙwayoyi dogara a kan gwada yawa abun ciki na aiki sashi da kwantena:

• 75 MG - 716,00 goga.;
• 110 MG - 1574,00 goga.;
• 150 MG - 1676,00 goga.