"Farmadipin" (saukad) daga abin da?

A halin yanzu, akwai mutane da yawa daban-daban magunguna domin hauhawar jini da kuma stenokardicheskie harin. Daya daga cikinsu shi ne ma kamar "Farmadipin" (saukad) magani. Menene wannan magani, tattauna kara a daki-daki.

tsarin

The aiki sashi a cikin wannan yanayin ne nifedipine (nifedipine). 1 ml na wannan bayani, shi ne a wani adadin. Wato, a 100%, bisa bushe-type abu - 20 MG. Sai dai talatin saukad.

"Farmadipin" (droplets), da wa'azi ga wanda da aikace-aikace da za a tattauna a kasa, a cikin tsarin da yake gaban karin abubuwa irin polyethylene glycol 400 da kuma 96% ethanol.

pharmacological Properties

Wannan magani yana da wani peculiar pharmacodynamics. Kamar yadda riga aka ambata a sama, da "Farmadipin" (saukad) ya ƙunshi nifedipine abu da samar da antihypertensive kuma anti-anginal mataki. Yana inganta tarewa shigarwa na alli ions cikin cardiomyocytes da santsi tsoka Kwayoyin a wasu gefe da kuma jijiyoyin zuciya arteries ta hanyar wani irin ƙarfin lantarki-type jinkirin Game da tashoshi na cell membranes. Wannan muhimmanci dukiya. Nifedipine kuma samar da shakatawa na jijiyoyin bugun gini m tsoka, ta ƙara gefe da kuma jijiyoyin zuciya arteries, da kawar da spasms. Wannan rage hawan jini, na tsari jijiyoyin bugun gini juriya, cardiac afterload da kuma tsokar oxygen bukatar. Har ila yau, a lokacin da shan wannan magani ya ci gaba da nuna wasu cututtuka. Wato, akwai wani kadan karu a tsokar contractility da kuma zuciya aiki, kazalika da da ɗan rage platelet tari.

Pharmacokinetics

A wannan batun, "Farmadipin" (saukad), da umarnin don amfani wanda aka dauke a cikin wannan rahoto, yana da halaye. Lokacin da wani ciki liyafar da yake da shi a cikin narkewa kamar fili da kyau tunawa. Its bioavailability ne game 40-60 bisa dari. A musamman m ci gaba sakamako (bayan 5-10 min) yayi a aiwatar da sublingual gwamnati. Yana da muhimmanci a san. Yawanci, mafi girma da sakamako da aka gani a 30-40 minti. Aiwatar da ingestion da aka ba musamman shafi cikin kudi na sha na da wakili. A buɗi na hemodynamic sakamako zai dage don 4-6 hours. Kamar haka kashi 90 cikin dari na nifedipine daure su jini jini sunadaran. Yana metabolized irin wannan shiri a matsayin "Farmadipin" (drop) a cikin hanta. A gaban total yarda da nifedipine ne daga 0.4 zuwa 0.6 l / kg / hr. An deduced daga jiki yafi a matsayin metabolites m irin. A tsawon rabin-rai za su iya bambanta daga 2 zuwa 4 hours. A tsofaffi da marasa lafiya da cirrhosis na hanta, nifedipine metabolism slows saukar muhimmanci. A sakamakon haka, suna da rabin-rai na nuna alama nufin za a iya ƙara kimanin 2-Musulunci. A wannan yanayin wajibi ne don rage kashi da kuma kara tazara tsakanin receptions na ce halitta. Nifedipinv jiki ba cumulated. Har ila yau shi a cikin wani karamin adadin zai iya shiga cikin jini-kwakwalwa da kuma placental shãmaki. A wannan yanayin, shi ne excreted a nono.

alamomi

Nada "Farmadipin" (drop) a cikin wadannan lokuta:

• A taron na da muhimmanci hauhawar jini da kuma symptomatic.
• Ga magani da kuma rigakafin stenokardicheskie harin.
• Lokacin da hypertrophic cardiomyopathy.
• Lokacin da Raynaud ta cutar.

aikace-aikace

Kai "Farmadipin" (saukad) sublingually. Lokacin da kaifi Yunƙurin a jini (msl, 180 / 100-190 / 110 mm Hg. V.), A guda na farko kashi na miyagun ƙwayoyi domin adult kullum ne kamar 3-5 saukad da (2-3,35 MG). Marasa lafiya da ci-gaba shekaru ne ma sanya wani takamaiman sashi. Wato - ba fiye da 3 saukad (game da 2 MG). Har ila yau, da kayyade yawan iya drip a kan wani karamin yanki na bushe abinci ko sugar. Ya haƙuri kamata rike dai zai yiwu a bakin. Tare da kasa sakamakon sashi daga cikin miyagun ƙwayoyi ne ta ƙara hankali har na asibiti inganci. A wannan yanayin, shi duka ya dogara da mutum. A m manifestations na kara hawan jini ya kamata a shiryar daidai da sa kashi. Har ila yau, akwai wani takamaiman rarrabẽwa. Shi ya ta'allaka ne da cewa idan jini ya tashi zuwa 190 / 100-220 / 110 mm Hg. v., sa'an nan shan miyagun ƙwayoyi saukad da za a iya hankali ya karu zuwa 10-15 (6,7-10 MG). Ya kamata ya yi la'akari da canje-canje a matsa lamba a ba haƙuri. Yana da muhimmanci a san.

Kana bukatar kuma ka yi la'akari da kasancewar ta ƙara ji na ƙwarai, a wasu marasa lafiya zuwa wannan miyagun ƙwayoyi a matsayin "Farmadipin" (saukad), wanda sake dubawa ne tabbatacce. A irin haka ne, da sashi aka zaɓi akayi daban-daban. Fara tare 3 saukad, sa'an nan a hankali tashe zuwa 2-3 (1,34-2 MG) har sai lokacin da idan ake so asibiti sakamako aka samu.

Ya kamata a tuna cewa a wuce haddi na farko kashi na miyagun ƙwayoyi iya haifar da wani kaifi karu a jini!

gefen sakamako

A cikin aikace-aikace na wannan shiri a matsayin "Farmadipin" (drop of matsa lamba), akwai iya zama bayyanar cututtuka na tashin zuciya, tachycardia, hypotension, "tides" na jini ga fuska. A wasu lokuta, na iya haifar da rashin lafiyan halayen a cikin nau'i na kafa edema, fata na gaggawa. Sun iya nuna bayyanar cututtuka na wani rauni, juwa ko jiri, ciwon kai.

contraindications

A liyafar da irin wannan magani, a matsayin "Farmadipin" (drop) an haramta gudanar da wani a gaban ƙara ji na ƙwarai to da aka gyara, cardiogenic buga, mai tsanani aortic da mitral stenosis, hypotension, tachycardia, kazalika a lokacin daukar ciki da kuma lactation.

yawan abin sama

A wannan yanayin, wasu daga cikin mummunan cututtuka na iya faruwa. Wato yawan abin sama da irin wannan kwayoyi a matsayin "Farmadipin" (saukad), za a iya tare da ya faru na zuciya rashin cin nasara, bugu, rayuwa acidosis kuma convulsions, mai kaifi digo a cikin jini. Lokacin da bayyanuwar wadannan cututtuka wajibi ne a koma ga wani gaggawa da matakan taimako. Sun kunshi a ciki lavage, kunna carbon, alli chloride da gabatarwar sympathomimetics, symptomatic far.

amfani Features

"Farmadipin" (drop of matsa lamba) ko canza shi da za a yi amfani na musamman tare da mai da hankali asibiti saka idanu na tsofaffi da marasa lafiya da kuma marasa lafiya da suke yi:

- m angina.

- tsanani zuciya rashin cin nasara.

- hypertrophic cardiomyopathy.

- M aortic stenosis.

- mai tsanani na huhu hauhawar jini.

- m bugun jini.

- Ciwon mellitus.

- koda aiki da kuma hanta.

A sashi na sauran magunguna amfani da su nifedipine ya kamata a kafa akayi daban-daban. Cardiac glycosides kuma za a iya amfani da a lokacin liyafar da irin wannan magani kamar yadda "Farmadipin" (saukad), analogs wanda aka nuna a kasa a cikin wannan rubutu.

A kan samun lokaci daya aikace-aikace na nifedipine da igiyar jini magnesium sulphate mata masu ciki da bukatar motsa jiki da hankali da lura da na jini. Wannan ya kamata a yi, saboda akwai yiwuwar ragewan jini da cewa zai iya cutar da biyu uwa da tayin.

Marasa lafiya da illa hanta aiki, kuma bukatar da hankali saka idanu. A tsanani lokuta, da kashi ya kamata a rage.

Nifedipine tsitohromichnuyu metabolized via da P450 3A4 tsarin. A sakamakon haka, da kwayoyi da cewa hana ko sa kayyade yanki enzyme iya canza sakamakon "na farko watsa" ko yarda da abu. Idan concomitant amfani da nifedipine da kwayoyi na irin wannan ya kamata a sarrafawa jini. Idan dole, ya kamata koma ga wani raguwa a sashi daga cikin miyagun ƙwayoyi, a matsayin "Farmadipin" (saukad).

Gudanar da raba gwaje-gwajen a vitro Mun saukar da wani aminci tsakanin amfani da alli antagonists a cikin wannan harka nifedipine da biochemical kishiya ma'ana canje-canje da shafi tabarbarewar da ikon na karshen su aiwatar da hadi.

Shan "Farmadipin" (saukad), shi ya kamata dena ayyukan yiwuwar m irin, bukata mafi girma da hankali. Wato, a lokacin da ba lallai ba ne ya fitar da motoci da kuma aiki tare da wasu sunadaran, da sauransu.

hulda

"Farmadipin" (droplet) yana mai hypotensive mataki. Wannan yanayin kara habaka da kwayoyi daga category blockers. Wannan shi ne, "Farmadipin" (drop) qara β-adrenergic effects, diuretics, nitrates, da kuma sauran antihypertensive jamiái, shirye-shirye da kuma abubuwan sha mai ƙunshe da barasa, tricyclic antidepressants. A wasu lokuta, nifedipine rage quinidine taro a jini jini. Amma da sokewa da yawa da shi qara. Saboda haka, ta amfani da hade far bada shawarar saka idanu da matakan quinidine maida hankali a cikin jini jini.

"Diltiazem" rage yarda da miyagun ƙwayoyi a matsayin "Farmadipin" (droplets). "Fentanyl" muhimmanci kara habaka bayyanuwar hypotensive sakamako. A sakamakon haka, kafin gwamnati da miyagun ƙwayoyi (a cikin kasa da 36 hours.) Ya kamata yanke liyafar "Farmadipina". Hadin gwiwa da yin amfani da β-blockers da nifedipine iya haifar da hypotension. "Farmadipin" (saukad) inganta taro na theophylline, carbamazepine da digoxin a cikin jini. "Rifampicin" kaiwa zuwa weakening na warkewa sakamako na nifedipine, haka mugun gudu up cikin hali na ta metabolism. "Cimetidine" kara habaka maida hankali "Farmadipina" a cikin jini jini.

Sharuddan da yanayi na ajiya

A wannan yanayin, akwai wasu sharudda. Store "Farmadipin" (drop) dole ne a dakin da zazzabi a bushe wuri. Da miyagun ƙwayoyi ne a kare su daga haske, kuma da isar yara. Storage wannan miyagun ƙwayoyi da aka tsara don har zuwa shekara 1 da watanni 6. Da zarar ya bude vial - 28 days.

holiday

"Farmadipin" (saukad da) za a iya gane kawai ta sayen magani.

shiryawa

A vials na 25 ml ko 5 ml. Sun kashe a wani gungu.

"Farmadipin" (saukad) analogues a Rasha

Akwai da yawa musanya ga miyagun ƙwayoyi. Babban wadanda su ne:

- "cordipin".

- "Nifedipine".

- "Adalat".

- "Kordafleks".

- "Corinfar Uno".

- "Kordafleks RD".

- "fenigidin".

- "Osmo-Adalat".

- "cordipin retard."

- "cordipin XL".

ƙarshe

Yanzu da ka san abin da kamar "Farmadipin" (drop) da magani, daga wanda ya taimaka da kuma abin da kaddarorin. A cikin wani hali, kafin shan wannan magani ya kamata shawarci wani m likita.