"Mesipol": umarnin don amfani, real takwarorinsu

Mene ne magani "Mesipol"? a kan aikace-aikace na kayan aiki jagora, ta Contra-alamomi da za a tattauna a wannan labarin. Har ila yau, za ka koyi ko ko ba da wannan magani illa cewa zai zama a taron na wani yawan abin sama, da tsari a cikin abin da shi ne kasuwanci da kuma abin da abu ya ƙunshi.

Form da miyagun ƙwayoyi da kuma abun da ke ciki

Shiri "Mesipol" da aka kasuwanci a biyu daban-daban siffofin: Allunan, kuma mafita ga intramuscular allura. Su aiki manufa ne guda. Idan ba shi yiwuwa baka gwamnati, allura da ake amfani.

The bayani "Mesipol" yana da wani aiki rabi kamar meloxicam. Yana kuma ya hada da wadannan karin sinadaran: glycofurol, meglumine, sodium chloride, Poloxamer 188, sodium hydroxide, glycine, da kuma ruwa ga allura.

The bayani yana mai launin rawaya ko greenish-rawaya. Shi ne m. Har ila yau yana da halayyar wari. A kartani ne 3 ampoules (1.5 ml).

Ba zato ba tsammani, ban da Allunan, ko mafita ga intramuscular injections, Pharmaceutical kamfanoni suka fara nuna kyandirori "Mesipol" da kuma suspensions yi nufi ga baka gwamnati.

A pharmacological halaye na da miyagun ƙwayoyi

"Mesipol" miyagun ƙwayoyi ne a nonsteroidal anti-mai kumburi wakili. A miyagun ƙwayoyi ne iya exert analgesic da antipyretic sakamako. A antiinflammatory sakamako na nufin hade da wani slowing na enzymatic aiki na cyclooxygenase-2, wanda aka hannu a cikin biosynthesis na prostaglandins a cikin inflamed yankin.

A kalla aiki meloxicam kashi abubuwa a kan cyclooxygenase-1, wanda aka kai tsaye da hannu a prostaglandin kira, abin da na tsare da mucous membrane na hanji da kuma abubuwa a kan tsari na jini ya kwarara a cikin koda.

Pharmacokinetics da miyagun ƙwayoyi

Drug "Mesipol" (injections da Allunan) da ake tunawa gaba daya. A bioavailability da miyagun ƙwayoyi ne 100%. Bayan intramuscular allura (game da 15 MG meloxicam), matsakaicin sha da aka kai bayan 65 minti.

muna la'akari da miyagun ƙwayoyi ta ɗaure zuwa jini sunadarai, ciki har da albumin (99%). Yana sauƙi wuce ta jini-nama shingen, amma kuma shiga cikin synovial ruwa. A maida hankali a cikinta ne 50% daga cikin miyagun ƙwayoyi taro a jini.

The aiki abu na medicament an kusan gama metabolized a cikin hanta. Wannan suranta hudu pharmacological m metabolite.

Bayan aikace-aikace na medicament daidai nuna hanji da kuma koda (a metabolite). A talakawan rabin-rai na aiki abu ne 20 hours.

Alamomi ga yin amfani da magunguna

A wasu lokuta, rubũta "Mesipol"? Umurnai na Amfani jihohin da mafi sau da yawa bayar da shawarar yin amfani da NSAIDs a symptomatic magani daga cututtuka kamar:

• osteoarthritis.
• rheumatoid amosanin gabbai.
• Ankylosing spondylitis (ko ankylosing spondylitis).

Bugu da kari, da miyagun ƙwayoyi "Mesipol" (injections da Allunan) ne sau da yawa wajabta ga sauran degenerative da kuma kumburi cututtuka na gidajen abinci, wanda suna tare da ciwo mai tsanani.

Contraindications da yin amfani da wadanda ba steroidal jamiái

A wasu lokuta, magani ba za a iya amfani da "Mesipol"? Umurnai na amfani ƙunshi wata babbar jerin contraindications. Wadannan sun hada da wadannan:

• Hypersensitivity da aiki kashi na magani ko ta karin aka gyara.
• m ko cikakken hade da fuka, rashin ha} uri na acetylsalicylic acid, polyposis (maimaita) paranasal sinus da hanci kogo, da kuma sauran NSAIDs, ciki har da anamnesis.
• yara shekaru (16-18 shekaru).

• ulcerative ko erosive raunuka na mucous membrane 12 tiperstnoj hanji ko ciki.
• nono.
• cerebrovascular zub da jini ko wasu zub da jini asalin;
• aiki na jini a cikin Gut ko ciki.
• a lokacin gestation (ciki).
• kumburi hanji cuta (msl Crohn ta cuta ko ulcerative colitis).
• m koda cuta, ciki har hyperkalemia (tabbatar da);
• lokaci bayan jijiyoyin zuciya jijiya kewaye tiyata.
• koda gazawar (bayyana) a cikin mutanen da suka yi ba, an hõre dialysis (CC kasa da 30 ml / min).
• decompensated zuciya rashin cin nasara.
• aiki ci gaban da cutar hanta ko hanta gazawar (tsanani).

Yi amfani da matsananci taka tsantsan!

Yanzu da ka san a wane lokuta za ka iya amfani da miyagun ƙwayoyi "Mesipol" (Allunan, injections), da kuma a cikin abin da shi ne contraindicated. Duk da haka, akwai yanayi inda muka dauke da miyagun ƙwayoyi ya kamata a gudanar da matsananci hankali. Ka yi la'akari da jerin irin haka:

• m shekaru (60 years).
• jijiyoyin zuciya da cututtukan zuciya.
• kullum zuciya maye.
• cerebrovascular cututtuka.
• ciwon sukari.
• dyslipidemia ko hyperlipidemia.
• gefe jijiya cuta.
• creatinine yarda kasa da 60 ml / min.
• shan taba.
• ulcerative raunuka na narkewa kamar tsarin a tarihi.
• dogon lokaci da yin amfani da wadanda ba steroidal kwayoyi, kazalika da su uncontrolled amfani a manyan allurai.
• kamuwa da cuta, da aka sani da Helicobacter pylori.
• yau da kullum amfani giya (ko da tare da wani low abun ciki na barasa).
• daya-lokaci amfani da baka corticosteroids, ciki har da "Prednisolone" miyagun ƙwayoyi.
• m somatic munanan;
• concomitant amfani da anticoagulants (msl, miyagun ƙwayoyi "Warfarin"), antiplatelet jamiái (msl, acetylsalicylic acid da kuma wani medicament 'Clopidogrel'), kazalika da hanawa (zabe) serotonin reuptake (ciki har da kwayoyi "Tsitmedialopram", "Fluoxetine", "paroxetine" da kuma "sertraline").

Nonsteroidal anti-kumburi miyagun ƙwayoyi "Mesipol": umarnin don amfani da

Intramuscular gwamnati na medicament kafin mu nuna ne kawai domin na farko 3 kwanaki da magani. A nan gaba, ci gaba da far da baka siffofin magani, watau Allunan.

Da shawarar sashi daga cikin wakili ne 7.5 MG ko 15 MG sau daya a rana. A ba adadin da miyagun ƙwayoyi dogara da tsanani da zafi, kazalika da tsananin daga cikin kumburi tsari. A medicament aka gudanar da zurfin intramuscular allura.

Shin yana yiwuwa a hada da wasu kwayoyi da miyagun ƙwayoyi "Mesipol" (Shots)? Umarni da miyagun ƙwayoyi ce da abinda ke ciki na vials a wani hali ba za a iya gauraye a cikin wannan sirinji tare da sauran mafita. Wannan shi ne saboda gaskiyar cewa akwai wani babban Yiwuwar incompatibility na aiki abu meloxicam tare da sauran likita gyara.

Ya kamata a lura da cewa a cikin marasa lafiya da suke da wani ƙãra hadarin m halayen, kazalika da koda gazawar (bayyana) a kan hemodialysis, a nonsteroidal miyagun ƙwayoyi sashi kamata ba zama ya fi 7.5 MG da rana.

Shi ne kuma dole mu tuna cewa miyagun ƙwayoyi "Mesipol", analogues na wanda za mu yi la'akari da kara, a wani hali ba za a gudanar da intravenously.

A kalla kullum kashi na meloxicam aiki rabi ya zama 15 MG. A wannan adadin medicament da za a bi da kuma hade da yin amfani da Allunan, suspensions, domin baka da gwamnati, suppositories, kuma intramuscular allura.

lokuta da yawan abin sama

Akwai lokuta da yawan abin sama daga yin amfani da "Mesipol" miyagun ƙwayoyi? Injections (reviews game da su za a gabatar a karshen cikin labarin), kwayoyi, suppositories da suspensions iya sa matalauta mutum idan amfani ba dama da kuma a cikin babban kundin.

Bayyanar cututtuka na yawan abin sama na iya hada wadannan yanayi: tashin zuciya, illa sani, epigastric zafi, m na koda gazawar da amai, zub da jini a ciki ko hanjinsu, hanta gazawar, asystole, kuma numfashi kama.

Abin da ya yi a idan akwai wani yawan abin sama? Masana sun bayar da shawarar ciki lavage, kazalika da symptomatic far.

Af, a cikin shakka daga asibiti karatu sun nuna cewa cholestyramine taimaka hanzarta kawar da meloxicam. Hemodialysis yawan abin sama ne m, tun akwai wani babban dangane da jini da sunadarai.

illa

Yana iya sa illa miyagun ƙwayoyi "Mesipol" (Shots)? a kan yin amfani da wadanda ba steroidal jamiái Guide ya furta cewa, shi zai iya sa wani babban yawan mummunan sakamakon. Bari mu bincika su, a cikin mafi daki-daki:

• Narkewa kamar fili: dyspepsia, zawo, tashin zuciya, perforation na narkewa kamar fili, ciki zafi, amai, flatulence, maƙarƙashiya, mai shudewa karuwa a transaminases (hanta), burp, hyperbilirubinemia, ulcerative ko erosive raunuka na narkewa kamar tsarin, esophagitis, stomatitis, bayyane ko boye zub da jini daga narkewa kamar fili, colitis, gastritis da kuma hepatitis.
• Skin: rash, pruritus, bullous rash, fata na gaggawa, photosensitivity, Stevens-Johnson ciwo, erythema multiforme, epidermal necrolysis mai guba.
• hemopoietic tsarin: anemia, thrombocytopenia, canje-canje a cikin jini kirga kuma leukopenia.
• Alerji: angioedema , kuma anaphylaxis.
• M System: vertigo, juwa ko jiri, da ruɗewa, da ciwon kai, wani tunanin lability, tinnitus, disorientation da drowsiness.
• Tsarin Numfashi: bronchospasm.
• Zuciya da jijiyoyin jini tsarin: a kara na jini ga fata, gefe edema, palpitations da kuma hawan jini.
• Gabobin da hangen nesa: Heart ko illa wahayi, conjunctivitis.
• Urinary tsarin: m na koda gazawar, hypercreatininemia ko karuwa a jini urea, interstitial nephritis, hematuria da albuminuria.
• Local halayen: zafi da kuma kona a shafin na intramuscular allura.

Hulda da sauran kwayoyi

• Lokacin da daya-lokaci amfani da sauran nonsteroidal kwayoyi da kuma acetylsalicylic acid kara hadarin miki da erosive raunuka na narkewa kamar fili, kazalika da zub da jini a cikinsu.
• Tare da lokaci daya da yin amfani da kwayoyi tare da antihypertensives ne wata ila don rage tasiri na karshen.
• Lokaci daya magani magani "Mesipol" tare da lithium far inganta jari na cikin karshen da kuma kara yawan mai guba effects.
• Lokacin da daya-lokaci aikace-aikace na "Methotrexate" wajen kara yawan illa a kan hematopoietic tsarin.
• Lokaci daya da yin amfani da miyagun ƙwayoyi "Mesipol" tare da diuretics ne hadarin na koda gazawar.
• Daya-lokaci amfani da cyclosporine qara nephrotoxic effects na aiki abu meloxicam.
• Tare da na lokaci daya amfani da intrauterine hana rage-rage tasiri na karshen.
• Lokacin da daya-lokaci amfani da wani anticoagulant da thrombolytic jamiái na kara hadarin zub da jini.
• Lokaci daya amfani da wani ba-steroidal miyagun ƙwayoyi "Mesipol" tare da kolestiraminom kara habaka ta tukar tumbi via da gastrointestinal gabobin. Wannan na faruwa a sakamakon Daure meloxicam.
• Yarwa da magani tare da mai hanawa na (zabe) serotonin reuptake muhimmanci ƙara hadarin zub da jini daga gastrointestinal fili.
• Myelotoxic kwayoyi kara da magana gematotoksichnosti aiki abu meloxicam.

Specific shiriya a kan yin amfani da kwayoyi

• Drug "Mesipol" ya zama tare da matsananci hankali a marasa lafiya tare da peptic miki na ciki da kuma hanjinsu, kazalika da mutanen da suke kan anticoagulant far.
• A lokacin jiyya da wannan magani dole don sarrafa sigogi na koda aiki, musamman a cikin tsofaffi da marasa lafiya da na kullum zuciya maye.
• Marasa lafiya a lokaci guda samun diuretics kuma yana nufin "Mesipol", ya kamata sha yalwa da ruwaye.
• Idan a cikin shakka daga far, da mãsu haƙuri bayyana allergies, kashi na magani ya kamata a katse.

Analogues da miyagun ƙwayoyi farashin

Nawa ne mu dauke da wani magani? A kantin injectable nau'i na da miyagun ƙwayoyi za a iya saya don 400 Rasha rubles. Amma ga Allunan, suspensions da kuma suppositories, su farashin ne kadan m.

Abin da idan ba za ka iya saya da miyagun ƙwayoyi "Mesipol"? Analogs daga kudaden da ake sayar a kusan duk drugstores. Daga cikin su akwai wadannan kwayoyi: "Amelotex", "Eksen-Sanovel", "Artrozan", "Matar", "M-Cam," "liberum", "Medsikam", "Melbek", "Melox", "Bi- Xico "," Meloxicam "," Melox "," Meloflam "," Miksol-Aude "," Mirloks "," Movalis "," Movasin "," Moviks "," Lem "," Oksikamoks "da sauransu.

"Mesipol": reviews na medicament

Yanzu ka san cewa shi ne da wani magani da muke son saye. Yana da lokaci don gano abin da marasa lafiya ce game da "Mesipol" shirye-shiryen. Reviews wannan nonsteroidal anti-kumburi shubuha wajen. A daya hannun, marasa lafiya da'awar cewa shi ne da sauqaqa zafi syndromes cewa ne muhimmi a osteoarthritis, rheumatoid amosanin gabbai, ankylosing spondylitis da sauran degenerative da kuma kumburi cututtuka na gidajen abinci. A daya hannun, marasa lafiya sau da yawa koka cewa da miyagun ƙwayoyi sa wani fairly manyan yawan illa, a sakamakon wanda su aka tilasta daina shan shi.

A general, da miyagun ƙwayoyi kafin mu "Mesipol" gaba daya copes tare da aiki da.