Twin hanyar

Twin Hanyar bincike amfani a cikin ganewa na ãyõyin hereditary yanayin conditionality. Wannan hanya ya nuna dangantakar da genotype da kuma muhalli. Twin halittar jini Hanyar yarda mana mu kimanta tamanin a kayyade predisposition zuwa yawa pathologies, expressivity, penetrance, da kuma yanayi na bayyanar da wadannan ko wasu daban na cututtuka. Research data suna da amfani a quantifying kayyade kaddara na (determinableness) wasu alamu. A wannan batun, da tagwayen hanya da aka dauki daya daga cikin mafi muhimmanci bincike hanyoyin in gwada yawa gādo.

Twins iya zama m. Suna kafa a lokacin farkon matakai na da rabo daga cikin zygote, a cikin abin da biyu (wani lokacin more) blastomeres ci gaba kwayoyin (full). M tagwaye bambanta genetically m.

Mawallafi na wannan bincike Hanyar ne dangana F. Galton.

Duk da kalubale, wanda yana da tagwayen hanya, a yau shi ba shi da fadi da m aikace-aikace kamar dā. Wannan shi ne saboda da gano mafi daidai da zamani bincike dabaru, kyale uniquely gano kwayoyin predisposition zuwa wani cuta.

Twin Hanyar shafi gwada da kuma dizygotic tagwayen monozygotic (zuriyarsa wanda qunshi biyu mutane haife dabbobi masu shayarwa singletons).

Monozygotic zuriya tasowa a cikin wannan hadu kwai. Wadannan tagwaye da 100% na su da kwayoyin halittu. Saboda haka, da bambance-bambance tsakanin gano su, ba su hade da wani hereditary factor. Development of dizygotic tagwaye faruwa a daban-daban oocytes cewa an hadu da daban-daban maniyyi. Wannan iri yana da 50% na jimlar genes a matsayin al'ada sibs (zuriyar biyu daga iyaye - Siblings). Duk da haka, a lokaci guda na da haihuwa, hadin gwiwa da ilimi siffofin da na kowa muhalli dalilai. Saboda haka, mataki na bambancin dizygotic zuriyarsa genotypes ƙaddara da digiri bambanci.

A kwatanta waɗannan ƙungiyõyi biyu daga tagwaye lasafta fihirisa mismatch (discordant) da kuma rubutu (concordance). Bugu da kari, mita ƙidãyar aka yi a wanda tasowa nuni ko cuta a cikin kowane rukunin sama hereditary.

Twin Hanyar ne zuwa kashi da dama, saukarwa:

1. Mataki daukan samfur.
2. A mataki na kayyade zygosity form.
3. Mataki na kimantawa da sakamakon by gwada nau'i-nau'i.

A bisa bincike Hanyar ya na bayar da muhimmanci a binciken da hereditary hali, da yawa dauke da kwayar cutar da kuma "multifactorial" (tasowa saboda dalilai da dama) pathologies.

A adam halittar jini da ake amfani ba kawai classic amma kuma a modified Hanyar daga cikin tagwayen binciken. Saboda haka, ya yi nazarin yiwuwa ga inganta dama fasaha fasali tare da m horo hanyoyin da iko amfani da abokin tarayya, kamar yadda a cikin binciken na ciwon sukari - da dabara na twin iyalansu.

Gadar hali m halaye na hankali da kuma hali dace lura a cikin zuriyarsa, ko raba a farkon jariri kawo dabam, kuma ba a ƙarƙashin rinjayar da sauran yanayi da kuma hulda da juna.

A lokaci guda m data za a iya samu ba ko da yaushe haka al'amarin. Wannan shi ne saboda din da bambance-bambance tsakanin maras tagwaye da tagwaye a kan wasu filaye, kazalika da zamantakewa da kuma m halaye a cikin tsari na ci gaba a cikin postnatal lokaci. Wadannan dalilai takaita da aikace-aikace na sama Hanyar.