Yara Progeria: Kuna da yara da damar?

Yara Progeria - wata cuta daga kwayoyin hali, manyan zuwa komowar canje-canje a cikin kayan ciki na tsarin saboda da bai kai ba tsufa na dukan kwayoyin. A karo na farko da cutar da aka gano da kuma aka bayyana a cikin 1889 by John. Hutchinson, kuma da kansa a 1904 da J. Guilford. Duk da cewa yara progeria - wata cuta musamman rare, tun da gano bayyana fiye da 150 lokuta. Kuma kowanne daga cikinsu a hankali karatu a babbar dama masana kimiyya.

Sai kawai daya daga cikin miliyan 7 jarirai likitoci gane asali ciwo na Hutchinson-Gilford. Yara Progeria yana bunkasa cikin sauri - kawai a shekara haƙuri ta jiki zamanai 5-9 shekaru. The yara a rare lokuta tsira zuwa shekaru 23 na shekaru, mutuwa daga cutar mafi hali na tsofaffi. A farko alamun "tsufa, yara" ya bayyana a cikin yara daga wani wuri shekaru (2-3 years).

Kamar yadda irin wannan magani ba ya zama, wato, magunguna ana nada kawai ga symptomatic magani daga gefen cututtuka. Amma masana kimiyya a duniya suna nazarin matsalar da ake neman tasiri hanyoyin da za a magance shi.

Halin yara progeria wadannan manifestations:

• kananan jiki.
• haske (13-22 kg).
• mafi kyau fata, ta hanyar abin da tasoshin bayyane.
• jinkirin-motsi gidajen abinci na hannuwansu da ƙafãfunsu.
• babban shugaban, amma a lokaci guda - kadan mutum.
• high-kafa sansani murya.

A Sanadin cutar

Duk masana kimiyya sun yarda da cewa yara progeria ba da wata cũta, an gaji. The duniya da aka sani kawai zuwa daya iyali, inda dukkan 3 yara gãdon ciwo.

Ba haka ba da dadewa an yi tunanin cewa kawai dalilin da "yara shekaru" - da maye gurbi na guda gene cewa an da hannu a cikin samuwar sunadaran lamin A. The cell nuclei aka gina a kan tushen furotin. A kan aiwatar da sauyi a prelamina A balagagge gina jiki da ciwon kasawa. Saboda haka, a sakamakon lamin A muhimmanci bambanta daga wata al'ada gina jiki. Wannan take kaiwa zuwa wani iri-iri na pathological canje-canje a cikin jikin yaron, wanda aka halin cuta Hutchinson-Gilford. Yara Progeria fara don ci gaba, haddasa bai kai ba tsufa.

Amma wasu masana kimiyya ya gano wani gene a cikin DNA, a maye gurbi wanda babu makawa zai kai ga cuta. Komowar matakai a BAF-1 gene -prichina cin lahani a cikin membrane Kwayoyin. Tun da BAF-1 ma interacts tare da wasu sunadarai, da maye gurbi a cikin tsarin sa disturbances a cikin sauran sunadaran.

Shin akwai wata dama?

Don kwanan wata, masana kimiyya da fuska mai wuya aiki kammala wani m nazarin aiwatar da gene maye gurbi. Kuma idan sun samu nasara, sai da rashin lafiya yara za su yi a real damar lashe wani yara progeria, da kuma likitoci - su hana ta abin da ya faru.

Ya kamata a lura cewa mutane da yawa marasa lafiya tare da suma begen samun ceto. Amurka masana kimiyya sun fara gwajinsu na anti-wannan cuta. Yana yiwuwa, duk da haka, da cewa ba kowane yaro zai iya rayuwa har zuwa wannan lokaci. Amma a cikin wani akwati, idan gwaje-gwaje ne nasara da kuma yara progeria aka ci, shi zai zama wata nasara ga duk waɗanda suke yin duk abin da domin ya cece su yara daga irin wannan mummunan cuta.