Da miyagun ƙwayoyi 'alli pantothenate': halaye da kuma amfani a magani

Pantothenic acid (sashi tsari - da miyagun ƙwayoyi "Alli pantothenate") kunshe a cikin rukuni na bitamin B. Wannan m, optically aiki ruwa, sosai narkewa a cikin ruwa, da aka readily cleaved karkashin mataki na zafi, acid da kuma alkalis.

Pantothenic acid da aka samu a abinci kuma an hada da na hanji microflora (Escherichia). Bayan sha shi shiga cikin jini, kuma an kwashe su a kai duk gabobin da kyallen takarda, aka ajiye a cikin hanta, jera a cikin myocardium, koda da kuma kwarangwal tsoka. A cikin jiki, zai fi dacewa acid hade tare da sunadarai ba da wani ɓangare na CoA (coenzyme A). fashewa kayayyakin da miyagun ƙwayoyi "alli pantothenate" excreted a cikin fitsari da kuma tumbi. Ba dole ne a ce cewa yawan zaba pantothenic acid ne ko da yaushe mafi girma daga abin da ya shiga jiki da abinci. Wannan shi ne saboda ta kwayan kira.

Pantothenic acid ne a bangaren na CoA, wanda ya kunshi sassa uku: cikin saura tiolamina, pantothenic acid, 3-phospho-5adenozin-5-diphosphate. CoA ne a key kashi a metabolism, ke taka rawa a cikin aiki na da Krebs sake zagayowar a cikin nazarin halittu kira da hadawan abu da iskar shaka na carbohydrates, lipids, glucosamine samuwar, acetylcholine, hippuric acid, porphyrins, da dai sauransu

Drug "Alli pantothenate" - dan kadan yellowish ko fararen foda da wani m dandano, odorless, mai narkewa a cikin ruwa. Mai ruwa-ruwa mafita daga thermally barga, amma hanzari rushe lokacin da fallasa su acid da kuma Alkali. Pharmaceutical shiri da aka samar kamar yadda Allunan, kuma foda mafita a vials.

Its pharmacological ayyuka shiri "Alli pantothenate" ya nuna bayan pantothenic acid canza kama zuwa coenzyme A, wanda ya samar da beta-hadawan abu da iskar shaka, m acid kira, oxidative decarboxylation, kuma tana mayar pyruvic acid da kuma ketoglutaric acetyl. Ya taimaka wa sha na glucose a cikin hanji, qara matakin na glycogen a cikin hanta, daidai a cikin hormonal matsayi da kwayoyin, musamman a lokacin daukar ciki.

A rashi na pantothenic acid a cikin jiki ne hana hormone aiki pituitary, adrenal gland shine yake da pancreas. A adrenal gland rage matakin steroid hormones, wanda samar da pigmentation na gashi kuma fata. Rayuwa cuta tsokani dermatitis, fata depigmentation. Degenerative canje-canje lura a cikin adrenal gland da kuma juyayi nama. Su kuma iya zama karye motor daidaituwa, worsen koda cuta, zuciya, hanjinsu da ciki. A farko Sanadin bitamin ƙarara ne kasa yawa na wannan bitamin a abinci, hanji cuta, da kuma shafe tsawon amfani da maganin rigakafi (sulfonamides, maganin rigakafi).

Babban asibiti ãyõyin a rashin pantothenic acid a cikin jiki - ciki, gajiya, gajiya, rashin barci, ciwon kai da tsoka zafi, tashin zuciya, zawo, flushing daga cikin fata tasha, duodenal miki. A rashi na bitamin rage immunological juriya da kwayoyin. Da wannan bango, sau da yawa sosai akwai numfashi cututtuka.

sau da yawa sosai, likitoci rubũta da miyagun ƙwayoyi "alli pantothenate" ga tsari na tafiyar matakai na rayuwa. Yarda a ce medicament polyneuritis, paresthesia, neuralgia, mashako, eczema, dermatitis, konewa, trophic ulcers, ciki toxicosis, da tarin fuka, hypothyroidism, pancreatitis, gastroduodenitis, da dai sauransu Medicine "alli pantothenate" da-jure ta cikin jiki. Domin enteral gwamnatin iya dyspeptic bayyanar cututtuka, ta hanyar parenteral (intramuscular allura) - soreness.

Oversupply na alli (hypercalcemia) na iya faruwa saboda tabarbarewa na endocrine gland (parathyroid gland shine yake). Hypercalcemia aka rajista a cikin tsofaffi. hypercalcemia Clinic iya bayyana a matsayin janar wani rauni, asarar ci, a wani lokaci ana lura cramps da maƙarƙashiya.