Da miyagun ƙwayoyi "Ofloxacin": haƙuri shedu. Umurnai na amfani da kwayoyin "Ofloxacin"

Shiri "Ofloxacin" ratings marasa lafiya wanda mafi yawa tabbatacce, wakiltar antimicrobial wakili daga kungiyar na fluoroquinolones m bakan da aiki. Da miyagun ƙwayoyi rinjayar da DNA gyrase - kwayan gutsure, samar da supercoiling sabili da haka da kwanciyar hankali na kwayoyin DNA (a sakamakon rashin jituwa a cikin DNA tufka mutu).

pharmacodynamics

Na nufin "Ofloxacin" - wani kwayoyin tasiri game da kwayoyin da cewa samar da beta-lactamase, kazalika da sauri-girma atypical mycobacteria. Don magunguna ne m, mafi gram-korau kwayoyin cuta, ciki har da kwayoyin da suke resistant zuwa methicillin da sauran maganin rigakafi. Streptococci, enterococci, kuma Mycobacterium da tarin fuka ne halin da m laulayi da miyagun ƙwayoyi "Ofloxacin". Reviews na likitoci nuna cewa a lura da anaerobic cututtuka sa ta peptostreptokokki, peptokokki da sauran anaerobes, da miyagun ƙwayoyi ne sau da yawa m.

Pharmacokinetics

A kan samun da medicament cikin sha ne cikakken (95 bisa dari) da kuma sauri. Bioavailability - fiye da 96 bisa dari. Relationship zuwa jini sunadaran - 25 bisa dari. Bayan daya zuwa biyu sa'o'i bayan baka gwamnati na cincirindo kai. Shi ne kashi-dogara: da guda amfani da ɗari biyu, hudu ko shida da ɗari milligrams na miyagun ƙwayoyi taro da aka bi da bi 2.5, 5 ko 6.9 ug / ml.

Abinci amfani iya shafar sha na gefen wani slowdown, amma babu wani gagarumin tasiri a kan bioavailability. Shiri "Ofloxacin" - wani kwayoyin ciwon babba girma na rarraba (ɗaya da ɗari galan), don haka da cewa gudanar shiri ne kusan cika adadin ratsa yardar kaina a cikin sel. A mafi yawa ne a kyallen takarda, jiki ruwaye da kuma gabobin: a cikin sel (alveolar macrophages, leukocytes), taushi da nama, fata, kashi, miciwa, pelvic da kogon ciki, yau, prostatic secretions, fitsari, bile. A medicament da ke shiga cikin placental da jini-kwakwalwa shãmaki, an secreted daga nono madara, da kuma cerebrospinal ruwa shiga a cikin wadanda ba inflamed da kuma inflamed kwakwalwa membranes (14 zuwa kashi 60 cikin dari).

Game da kashi 5 cikin dari na miyagun ƙwayoyi ne metabolized a cikin hanta ta samar da dimetilofloksatsina kuma N-oxide na ofloxacin. Ko da kuwa da kashi rabin rayuwa ne tsakanin hudu da rabi zuwa bakwai hours. Fitarwa canzawa miyagun ƙwayoyi a cikin wani adadin 75-90 bisa dari na kodan, a cikin wani adadin 4 kashi - a cikin bile. Kasa da kashi 20 cikin dari na extrarenal yarda. Bayan guda kashi na biyu da ɗari milligrams na wakili ne detectable a cikin fitsari for 20-24 hours. A cikin hali na hanta ko koda tukar tumbi iya ragae. Lokacin da dialysis an cire ta 10 zuwa kashi 30 cikin dari na magani.

alamomi ga

A dauke da kwayar cutar da kumburi cututtuka da lalacewa ta hanyar daban-daban kwayoyin, nuna amfani medicament "Ofloxacin". Reviews sun ruwaito cewa yana da matukar kyau ga numfashi fili cututtuka (ciwon huhu, mashako), babba numfashi fili (otitis kafofin watsa labarai, sinusitis, laryngitis, pharyngitis). Sanya miyagun ƙwayoyi a taushi nama raunuka, gidajen abinci, ƙashi, fata, biliary fili, urinary fili (urethritis, cystitis), koda (pyelonephritis), kogon ciki, genitalia (orchitis, colpitis, epididymitis), pelvic gabobin (salpingitis, prostatitis, cervicitis, endometritis, oophoritis, sigogi).

Har ila yau tasiri magani ga ureaplasmosis, chlamydia, kabba da ciwon sanyi. Amfani da shi don rigakafin cututtuka a marasa lafiya da cuta da na rigakafi da matsayi (ciki har da neutropenia).

A sashi form. tsarin

A saki medicament ne a cikin nau'i na mai rufi fari ko kusan fararen film-rufi Allunan biconvex zagaye siffar. A gicciye bangaranci m biyu yadudduka, daya daga wanda yana da yellowish tint. Active bangaren abubuwa a matsayin ofloxacin. Daya kwamfutar hannu dauke a cikin taro na 200, ko 400 MG. Ƙananan sinadaran ne primelloza (croscarmellose sodium), microcrystalline cellulose, Aerosil (colloidal silicon dioxide), silica titania, povidone, hydroxypropyl methylcellulose (hypromellose), talc, magnesium stearate, polyethylene glycol 4000 (macrogol). A babban amfani da miyagun ƙwayoyi "Ofloxacin" - farashin. Allunan dauke da 200 MG na aiki abu ne da matsakaita na 16-20 rubles da 10 guda, da kuma wadanda ke dauke da 400 milligrams ofloxacin, za kudin game 50-55 rubles da 10 guda.

"Ofloxacin" magani. Umarnin don amfani

Allunan kamata sha kafin ko bayan wani gari. Su dole ne a yi lõma da dukan, ba tare da daukan taban, da kuma sha ruwa a kananan yawa. A sashi ya kamata a zaba akayi daban-daban dangane da tsananin daga cikin cuta, da sarrafawa da kamuwa da cuta, da mãsu haƙuri ta janar yanayin, koda aiki, hanta, da kuma kwayoyin ji na ƙwarai.

Matsayin mai mulkin, da magani daga "ofloxacin" An sanya bakwai zuwa kwanaki goma. Adult kullum wajabta ci biyu da ɗari, mutum ɗari shida da milligrams sau biyu a rana. A kashi iya karu zuwa takwas milligrams a cikin hali na mai tsanani kamuwa da cuta, ko idan haƙuri ne kiba. A kashi na hudu milligrams za a iya dauka a lokaci daya, zai fi dacewa da safe.

Marasa lafiya da illa na koda aiki da zarar ba zai iya daukar fiye da ɗari biyu milligrams na miyagun ƙwayoyi, da matsakaicin kashi kullum a hanta hanawa - ɗari huɗu da milligrams. Bayan bacewar cututtuka da kuma daidaita zazzabi, har ma ga kwana biyu ko uku kamata ci gaba da far.

Side effects. shedu

Ba dukan marasa lafiya da miyagun ƙwayoyi "Ofloxacin" da kyau jure. Sharhi kan wasu mutane dauke da bayanai da cewa da miyagun ƙwayoyi sa ciwon kai, tashin zuciya da amai, zawo, tremors, numbness na extremities. A kan wani ɓangare na narkewa kamar tsarin iya ci gaba kamar yadda ciwon mara, gastralgia, bloating, cholestatic jaundice, anorexia, hyperbilirubinemia, pseudomembranous enterocolitis, da kuma juyayi tsarin - rashin motsi, cramps, m mafarkai, psychotic halayen, agitation, tashin hankali, rudani, phobias, hallucinations, ciki.

Bugu da kari, akwai hadarin keta daga cikin mota tsarin (arthralgia, tendonitis, myalgias), hankula (dandano cuta, launi hangen nesa, ji, balance, kamshin), jijiyoyin bugun gini tsarin da zuciya (raguwa a jini, tachycardia), da fata (dermatitis, batu hemorrhage, papular rash), na hematopoiesis (thrombocytopenia, anemia, leukopenia). Bayan samun "Ofloxacin" miyagun ƙwayoyi (reviews tabbatar da wannan), a wasu lokuta yana bayyana itchy fata, bronchospasm, urticaria.

contraindications

Karbar medicament haramta rashin ha} uri ofloxacin da sauran fluoroquinolone Kalam, a cikin hali na rashi na glucose-6-phosphate dehydrogenase, epilepsy, raunuka na tendons, Munã rage kãmun bakin kofa. Bugu da kari, ba za ka iya yi da miyagun ƙwayoyi "Ofloxacin" ciki da kuma lactating mata, yara yan kasa da shekaru goma sha takwas. Tare da hankali shiri an wajabta, a Sistem sakulasan cuta a cikin kwakwalwa, cerebral jijiyoyin bugun gini atherosclerosis, koda gazawar a kullum CNS raunuka kwayoyin halitta.

Medicament "Ofloxacin" a wani ureaplasma. reviews

Babban abu ne cewa mutane su ce, amfani da samfurin - yana da ya sauri sakamako. Marasa lafiya bayar da rahoton cewa sakamakon shi ne m riga a ta uku ko hudu rana. Amma wajibi ne a yi gargaɗi da cewa wannan ba yana nufin farko na magani. Wadanda marasa lafiya da suke yi tsaya sha Allunan, ba tare da ta da cikakken shakka, sa'an nan a sake samu ureaplasmosis bayyanar cututtuka, saboda kwayoyin cuta ba da aka gaba daya shafe ta.

tsõratar

Lokacin da ciwon huhu tsokane ta pneumococcus, da miyagun ƙwayoyi m. Har ila yau, shi ne ba a nuna domin lura da m tonsillitis. Wajibi ne a dakatar da miyagun ƙwayoyi idan a kan bango da ya m fuskanci wani rashin lafiyan dauki, da CNS cuta, pseudomembranous colitis. Mata da ake ji nufin "Ofloxacin", shi ba da shawarar yin amfani da tampons, domin a cikin wannan harka akwai wani ƙãra hadarin tasowa thrush.