Hypothalamic sakewa hormones

Sakewa hormones ne mutum neurohormone cewa an hada hypothalamic tsakiya. Sun hana (statins) ko rura (liberiny) samar da Tropic pituitary ji ba gani. Yana activates da endocrine gland, kuma akwai tsari na saki na ba ji ba gani. A mafi girma sassa na tsakiya m tsarin da kuma tsarin endocrine suna a hankali alaka saboda sakewa ji ba gani.

hypothalamic aiki

Daya daga cikin muhimman aka gyara na da endocrine tsarin alhakin samar da hormones - da hypothalamus. Samar da hypothalamus abubuwa ne hormones da hannu a tafiyar matakai na rayuwa ta jiki.

A hypothalamus akwai jijiya Kwayoyin cewa tabbatar da samar da zama dole abubuwa na jiki na bukatar al'ada aiki. Wadannan Kwayoyin suna kira neurosecretory. Su aiki - to sami hatsaisai cewa aika da sassa daban daban na cikin juyayi tsarin. Kadaici abubuwa na faruwa ne ta aksovazalnye synapses.

Samar da hypothalamic sakewa hormones, ko kamar yadda aka kira su daban, statins da liberiny, suke da muhimmanci ga al'ada aiki na pituitary gland shine yake. By su sinadaran halitta, su ne peptides. Saboda sinadaran da jijiyar ne su kira, suna hawa a cikin jini da pituitary hypothalamic-pituitary tsarin.

rarrabuwa na hormones

Ka yi la'akari da mafi yawan sanannun sakewa hormones:

• Inhibiting mugunya na pituitary aiki - shi ne mai somatostatin melanostatin, prolaktostatine.
• Stimulant - muna magana ne game da melanoliberine, prolaktoliberine, folliberine, lyuliberine, somatoliberin, thyrotropin-sakewa hormone, gonadotropin-sakewa hormone da corticotropin.

Wadannan abubuwa, ko kuma wajen wasu daga cikinsu, za a iya wajen samar da sauran jikinsu, ba kawai hypothalamus (msl, pancreas).

Statins da liberiny

The aiki na pituitary gland shine yake shi ne kai tsaye dogara a kan su. su ma suna da wani tasiri a kan aiki na gefe endocrine gland:

• thyroid.
• ovaries a 'yan mata;
• testes a cikin maza.

Statins da liberiny wanda mafi kyau da aka sani su ne:

• dopamine.
• GnRH (lyuliberin, folliberin).
• melonostatin.
• somatostatin.
• tireoliberin.

Mugunya luteinizing hormone da follicle-haramta motsa hormones da pituitary GnRH samar.

A kan aiki na androgen a maza kuma zai shafi GnRH, taimakawa ga wata karuwa da maniyyi aiki da kuma matakin na libido.

Kuma mata neurohormone alhakin hailar sake zagayowar, da adadin hormones dabam tare da lokaci na zagayowar shi.

Ƙarancin samar da sakewa hormones sau da yawa yana sa rashin haihuwa da kuma rashin ƙarfi.

Halaye na hormones

Corticotropin hormone alhakin ji na tashin hankali, samar da hypothalamus. Wannan shi ne wani muhimmin sakewa factor, mukaddashin a tare da tare da pituitary hormones da su effects a kan adrenal gland. Mutane da rashin wannan hormone sau da yawa fama da hauhawar jini, da kuma adrenal insufficiency.

GnRH - a hormone da kara habaka samar da gonadotropins - ma wani samfurin na hypothalamus. Haka kuma an kira gonadotropin-sakewa hormone.

A al'ada aiki na haihuwa gabobin ba zai iya yi ba tare da GnRH. Yana da wannan hormone ne alhakin da na halitta Hakika na hailar sake zagayowar a mata. Tare da sa hannu daukan sanya aiwatar da maturation da saki da kwai. Wannan hormone ne alhakin libido (jima'i drive). Lokacin da akwai kasa samar da hormone da hypothalamus a mata sau da yawa ci gaba rasa haihuwa. Abin da kuma aka sakewa hormones?

somatoliberin

Mafi hanzari saki a cikin shimfiɗar jariri, da kuma samartaka. Its main alama ne tsari na daidaita sashin jiki girma da kuma jiki ta tsarin. Daga da samar da dogara a kan cikakken ci gaba da kuma samuwar da yaro. Ƙarancin samar da hormone daga hypothalamus iya kai wa ga wada (wada).

Prolaktoliberin

Da ya fi aiki ci gaban auku a lokacin gestation kuma a ko'ina cikin ciyar lokaci na mahaifiyar jaririn. Wannan sakewa factor daidai a samar da prolactin, forming ducts na mammary gland.

Prolaktostatin

Prolaktostatin tana nufin wani subclass na statins samar da hypothalamus, shi ne alhakin da hanawa na prolactin.

By prolaktostatinam sun hada da:

· Dopamine.

· Somatostatin.

· Melanostatin.

Su main mataki ne da nufin suppressing da Tropic hormones da pituitary da hypothalamus.

Melanotropin-sakewa hormone

A kan aiwatar da melanin pigment da kuma rabuwa na sel rinjayar melanoliberin. Ya kuma abubuwa a kan abubuwa na DWP pituitary.

Tasirin neurophysiological hali. Ana amfani da cire lura da depressive jihohin da parkinsonism.

Thyrotropin-sakewa hormone (TRH)

By thyrotropin-sakewa hormones na hypothalamus kuma ya shafi thyroliberine. Yana inganta samar da hormones na agara pituitary thyritropic.

Don a kananan har musababin aiwatar da prolactin. Thyroliberine kara habaka da taro na thyroxine a cikin jini.

CNS yana da babban tasiri a kan matakai na samar da hormones. Domin samar da neurohormones ne alhakin neurosecretory cell dokokin tsarin.

Basic ayyuka liberinov

Wannan hypothalamic sakewa ji ba gani. Yi tsara ayyuka. GnRH normalize aiki na haihuwa tsarin na mata da maza.

Su ke da alhakin haifuwa na follicle-haramta motsa hormone da rinjayen aiki na testes da kuma ovaries.

Irin wannan bangaren kamar yadda lyuliberin, ya fassara na ware sakamako a kan ovulation, forming yiwuwar fetal ganewa.

Mata suke sha'aninsu dabam da m rayuwa, da kuma lyuliberin folliberin samar a cikin kasa yawa.

Akwai kuma sakewa dalilai da suka shafi cikin talakawan rabo na hypothalamus, amma su dangane da pituitary agara pituitary Kwayoyin da ba a karatu.

Agonists sakewa hormone: kwayoyi

Kamar yadda muka rigaya muka gani, wadannan hormones samar da hypothalamus. Lokacin shi ne ake so a ta da ovaries, misali kafin IVF hanya, amfani agonists ko corticotropin sakewa hormone analogs. Wancan ne, suna da a jiki guda sakamako kamar yadda da kansa hormone.

Amma chances na m halayen a kan wani ɓangare na mace jiki. Wannan ya faru saboda ƙananan estrogen matakan. Mafi na kowa effects sun hada da:

• ciwon kai.
• wuce kima sweating.
• zafi filasha.
• farji rashin ruwa.
• yanayi swings.
• ciki.

Kwayoyi suna amfani kamar haka:

• "Diferelin" shi ne wani wucin gadi decapeptide analogue na halitta hormone sakewa.
• "Dekapeptil" kamar yadda wani ɓangare na wani triptorelin, wani wucin gadi analogue na GnRH. A rabin-rai daina. Sau da yawa amfani ga barbaran alura.
• "Lyukrin daffo" - leuprorelin. Yana yana da anti-estrogen, anti-Androgenic sakamako, warkar da endometriosis, hormone-dogara marurai - ciwon daji na prostate, igiyar ciki fibroids. "Lyukrin daffo" rage taro na testosterone a maza, estradiol a mata, a Bugu da kari, damuarn incretia pituitary FSH, LH.
• Effect da miyagun ƙwayoyi a hankali ya mayar da physiological mugunya ji ba gani.
• 'Zoladex' - roba analogue na da wata halitta hormone-sakewa hormone (LH). Sau da yawa amfani da IVF. Rage taro na estradiol a cikin jini, wannan ya auku saboda danniya na LH mugunya agara pituitary.
  

Mun tattauna shirye-shirye agonists sakewa hormone.

antagonists

Tun lokacin da samun sakewa hormone agonists ƙaruwa ƙwarai da gaske estradiol iya faruwa ba zato saki luteinizing hormone. Wannan take kaiwa zuwa bai kai ba ovulation da kuma lalata qwai. Don kauce wa wannan, da antagonists sakewa hormone amfani. A sakamakon ayyukansu iya ta da da pituitary gland shine yake sake. Ovarian hyperstimulation ciwo ba bayyana kanta, amma shi ne haka sau da yawa haka al'amarin saboda da shafe tsawon amfani da GnRH agonists. An gudanar a cikin kwanaki biyar daga farkon aikace-aikace na follicle stimulating hormone.

Don far ne nasara, duk-manufa shirye-shirye kamata kawai ya zama gwani.