4 (free): na kullum. Hormone T4 (free): da jini gwajin for thyroid hormones

Na bayar da muhimmanci a cikin al'ada aiki na thyroid gland shine yake ne hypothalamic-pituitary thyroid tsarin. Yana bayar da iko da kira, samar da ayyuka na thyroid ji ba gani.

Overview

A hypothalamus secretes kitse (tireotro-fil-sakewa factor). Yana, bi da bi, stimulates saki da kuma kira na thyroid haramta motsa hormone (TSH - TTG). TSH ne da hannu a cikin matakai hade tare da wasu steroids. A musamman, shi stimulates mugunya, jari, metabolism da kuma kira na triiodothyronine (T3) da kuma thyroxine (T4). Fiye da 99% na wadannan biyu steroids a cikin jini zagawa da a hade kai sunadaran form. Kasa da kashi daya ne a cikin free form. Sakakken steroid matakai a mafi yawan mutane da aka juna da aikin jiha na thyroid gland shine yake.

Properties thyroxine

Hormone T4 (free) facilitates tsari na al'ada girma da kuma ci gaba, da tabbatar da gyaran jiki zafin jiki da kuma game da shi rike da zafi buildup. A fili yana da wani sakamako a kan duk matakai na carbohydrate metabolism, a sashi - a kan bitamin da kuma sia metabolism. Hormone T4 (free) ne wani muhimmin bangaren da ci gaba a utero da neonatal lokaci. A taro na nuna asibiti yanayin thyroid matsayi, matsayin canji a cikin general matakin na thyroxine iya jawo da disturbances a cikin ayyuka na thyroid gland shine yake, ko da canji a cikin yawan kai sunadaran. A lokacin da rana, da matsakaicin abun ciki na steroid aka ƙaddara daga 8 zuwa 12 hours, da kuma m - tare da 23 da kuma 3. A lokacin shekara, matakin qarshe 4 (free) ya kai daga Satumba zuwa Fabrairu, mafi ƙasƙanci - bazara. A prenatal lokacin (lokacin gestation) thyroxine taro ya karu, kai wani matsakaicin matakin to hankali na uku trimester. Cikin rãyuwar thyroxin abun ciki a cikin mutane ko da jinsi da ya rage gwada m. Rage hormone matakan kiyaye bayan shekara arba'in.

Abin da zai iya gaya matakin thyroxine?

Idan T4 (free) a fili ya karu, sa'an nan an dauke da wani tabbaci na hyperthyroidism. Rage taro nuna hypothyroidism. Da 'yancin kai na steroid abun ciki na thyroxine dauri globulin sa ya yiwu don amfani da shi a matsayin abin dogara da bincike gwajin. Wannan ne da muhimmanci musamman a yanayin da suna tare da canje-canje a cikin matakan thyroxine-dauri globulin. Wadannan sun hada da na baka hana (baka), ciki, da samun androgen ko estrogen. Canje-canje ne halayyar da kuma ga wadanda suke tare da wani hereditary predisposition don ƙara ko rage taro na globulin. Bada gudumawar jini for free T4 bada shawarar ga ganewar asali da irin sakandare hypothyroidism saboda pathologies a hypothalamo-pituitary matakin. A wannan yanayin TTG ciki bai canza ko ƙaruwa. Yawanci, da darajar matakan thyroxine iya zama saboda high matakan da magani bilirubin, kiba, kazalika da tourniquet, a lokacin da za ta jini gwajin. 4 (free) bai canza a karkashin mai tsanani cututtuka a ba thyroid aiki. A matakin na jimlar thyroxine zai iya rage.

Shiri domin awon gwaji

A watan kafin bada jini zame gwamnatin hormones (sai dai idan akwai takamaiman umarnin endocrinologist). Domin kwanaki biyu ko uku da ta dakatar da yin amfani da bincike na aidin-dauke da kwayoyi. Jini dole wuce kafin radiological nazarin yin amfani da bambanci jamiái. A kan Hauwa'u na bada jini kamata dena jiki aiki, kashe stressful yanayi. Kafin binciken, rabin awa, ya kamata ka kwantar da hankali, sa numfashi zuwa al'ada. A analysis aka yi a kan komai a ciki. Tare da na karshe abinci dole ba kasa da awowi takwas, (amma zai fi dacewa 12 hours). Yana ba a yarda ya sha kofi, shayi, ko 'ya'yan itace. Can kawai ruwa.

Rage matakan thyroxine

4 (free) (al'ada mata da maza - 9-19 pmol / l) za a iya rage a cikin postoperative lokaci, a lokacin da sakandare hypothyroidism (kumburi da pituitary, tireotropinome, ciwo, Sheehan). Rage taro shi ne kuma lura a kan tushen da liyafar anabolics, thyreostatics, anticonvulsant kwayoyi, lithium shirye-shirye. Thyroxine matakin rage-rage a lokacin da yin amfani da baka hana, octreotide, methadone, clofibrate. Yiwu haddasawa kuma sun hada da rage cin abinci tare da wata iyaka adadin furotin, aidin rashi, tabar heroin amfani, daukan hotuna zuwa kai. 4 (free) iya rage tare da manyan (jijiya hypothalamus TBI), tsiwirwirinsu, nakasar hypothyroidism (tsakiyan m resection na ƙari kuma thyroid, autoimmune thyroiditis, wadan goiter).

Kara yawa

A matakin na irin hormone a matsayin T4 (free) (al'ada mata da maza aka nuna a bisa) iya ƙara a lokacin da mai guba goiter, TSH-m hyperthyroidism, kiba. Kara taro lura a bango na nephrotic ciwo, heparin far. Dalilan kuma sun hada da choriocarcinoma, liyafar da wani thyroxine a kan tushen da hypothyroidism, post-Natal canji a ayyuka na thyroid gland shine yake, na kullum cutar hanta. 4 (free) za a iya ƙãgãwa a thyroid juriya ciwo steroids, kwayoyin dizalbunemicheskoy hyperthyroxinemia, ya furta, sa wani karu tiroksinsyazyvayuschego globulin taro.

Thyroxine da ciki

Thyroid hormones suna da hannu a kusan kowane tsari a cikin jiki. Kamar yadda aka ambata a sama, da mahadi tsara metabolism, shafi na ayyuka na sauran steroids. Thyroid Pathology za a iya tare da duka biyu da karuwa da kuma raguwa a cikin ta ayyuka. Na musamman muhimmancin a take hakkin Gabar ayyukan da a lokacin haihuwa. The canji na aikin jiha na thyroid gland shine yake rinjayar cikin shakka daga ciki, ta hali, da kuma sakamakon da matsayi na jariri. Da wuya vynashivanie wuce lokacin da ya bayyana endocrine pathologies. Cututtuka irin wannan, kamar yadda mai mulkin, kai ga haihuwa tabarbarewa, rashin haihuwa. Mafi sau da yawa bincikar lafiya a lokacin daukar ciki goiter (wani karuwa a thyroid yaxuwa hali) da euthyrosis adana, kazalika da autoimmune thyroiditis, har suka sa canje-canje a cikin hormonal bango. Domin prenatal lokaci ne halin da canje-canje a cikin aikin jiha na gland shine yake.

shawarwari

Don daidai fassara sakamakon awon gwaje-gwaje a lokacin daukar ciki ya kamata ya yi la'akari da wasu maki. Tabbatar da dalilin da total T3 da T4 ba m. Wannan shi ne saboda gaskiyar cewa a lokacin daukar ciki, su maida hankali ne ya karu da rabin. Lokacin da bukatuwa izuwa thyroxine matakin nazari ta maida hankali ya kamata a ƙaddara a tare da tare da abun ciki TTG. Thyroxine da ɗan ƙara a game da 2% na mata masu juna biyu. A farkon rabin wata al'ada prenatal lokacin alama rage TTG (kamar 20-30% da marasa lafiya da singletons da kuma dukkan lokuta na mahara ciki). A lura da hyperthyroidism T4 diddigin kawai (free). Sakakken thyroxine matakin a baya, saukarwa iya marginally rage. Kamar wancan TSH taro za a kiyaye a cikin al'ada kewayo.