A mafi kyau misalin "cordarone" a Rasha

Jiyya na zuciya kari cuta - hadaddun likita matsalar da aka ba a warware har karshen, ko da a yau. Akwai da yawa anti-arrhythmic kwayoyi, amma suna da yawa contraindications da sakamako masu illa, saboda abin da na iya tabbatar da su zama masu hatsarin gaske ga haƙuri da rashin lafiya. Akwai dukan kungiyoyin na kudi yi nufi ga taimako daga arrhythmias, na rai barazana, amma su yi amfani da na dogon lokaci da aka ba da shawarar saboda da karuwa sakamakon daga rikitarwa samun magani. Haka kuma, marasa lafiya bukatar wani abin dogara, m, amma mun gwada lafiya magani, ko da wani analog daga gare ta.

"Kordaron" - wani tasiri antiarrhythmic miyagun ƙwayoyi

A cewar daban-daban karatu, "Kordaron" shi ne mafi inganci da miyagun ƙwayoyi da sauran irin kayayyakin, yana mai tabbatar da ikon rage mace-mace a cikin marasa lafiya da cardiac cuta. Ana amfani da nasarar da magani daga kusan duk cardiac arrhythmias. Daga cikin likitoci, ya ke dauke da nasa tarihin ga anti-arrhythmic kwayoyi aji III. Bugu da kari ga wani antiarrhythmic, antianginal sakamako yana da, tun da farko da aka kafa a matsayin magani domin lura da jijiyoyin zuciya da cututtukan zuciya.

Yana yana da ba kawai da sakamako halayyar da aji III antiarrhythmics, Ina nufin kawancen na potassium tashoshi, amma mataki, halayyar ga aji na kayayyakin, - kawancen na sodium tashoshi, IV aji - kawancen na alli tashoshi. Daga cikin abubuwan, da miyagun ƙwayoyi ba alpha- da beta-adrenoceptor tarewa, jijiyoyin zuciya dilator sakamako.

alamomi

The aiki sashi daga cikin miyagun ƙwayoyi - amiodarone. Ciniki sunan - "Cordarone." Analogs samar da wasu sunaye, amma dauke da wannan aiki abu. Amiodarone aka samar a cikin nau'i na bayani ga igiyar jini allura, da Allunan.

The bayani ne amfani a yanayin saukan a lokacin da wajibi ne a daina kai hare-hare na na ramin zuciya da kuma supraventricular tachycardia, atrial fibrillation, ciki har da seizures. Allunan aka yi amfani da rigakafin na ramin zuciya da kuma atrial arrhythmias da paroxysmal tachycardia.

manufa na aiki

By suppressing aiwatar da kwayuka kai na potassium ions, da miyagun ƙwayoyi prolongs da uku lokaci na mataki m na zuciya tsoka Kwayoyin. Yana kuma cike da watsa daga cikin lantarki bugun jini a cikin zaruruwa na atrioventricular kumburi. Saboda wannan, bugun jini slows saukar. A sakamakon haka, da m tarewa sakamako daga cikin m juyayi tsarin slows da zuciya rate.

Amiodarone aka metabolized a cikin hanta da kuma excreted yafi a fitsari. Matsakaicin abun ciki na aiki abu lura bayan 3-7 hours bayan ingestion na kwamfutar hannu. Ci warkewa sakamako bayyana ba a baya fiye da mako daya bayan da farkon magani.

Analogs "cordarone"

A lokuta da dama, da marasa lafiya domin daban-daban dalilai fi son asali miyagun ƙwayoyi da kuma ta equivalents, generics. Tun "Kordaron" - kawai wani fatauci sunan amiodarone, yana shan wahala daga arrhythmias sau da yawa mamaki ko akwai kwayoyi analogues "Cordarone."

Game amiodarone, da tambaya da ta analogues ne musamman dacewa, domin shi ne daya daga cikin rare kwayoyi a duniya na cardiology, yana da fadi da aikace-aikace. Wadannan kwayoyi, kamar yadda aka ambata a sama, da karin illa, sau da yawa tabarbarewar kiwon lafiya. Saboda haka, likitan da haƙuri shi ne sha'awar shi ne a zabi miyagun ƙwayoyi da iyakar yadda ya dace da kuma m hadarin rayuwa da reshe. Idan kana neman m miyagun ƙwayoyi "Kordaron" takwarorinsu, da sake dubawa na likitoci a cikin wannan harka dole ne ka ga m, ko da yake, ba shakka, real marasa lafiya ma suna da muhimmanci, tun da sun iya gaya maka yadda za su ji a lokacin liyafar da kuma gudun farko na kyautata. Tare da wannan magani a matsayin "kordaron" ko wani daga cikin analogs kamata a tare da likita dubawa da kuma kula da kiwon lafiya na matsayi, ciki har da ta wajen wani ECG.

Yana taka muhimmiyar rawa da kuma abun da ke ciki na miyagun ƙwayoyi. Alal misali, aidin, wani ɓangare na amiodarone ne contraindicated a yawan cututtuka. Har ila yau, zai iya karkatar da sakamakon wasu karatu. Ba abin mamaki ba cewa da yawa wahala daga arrhythmia neman analogue "cordarone" ba tare da aidin kamar 'dronedarone. " Hakika, maye gurbin duk wani magani ne kawai bayan tuntubar likita. Saboda haka, da yawa Rasha masana ba da shawarar a zabi "Dronedarone" unnecessarily, kamar yadda shi ne mai rauni analog "cordarone". A Turai, duk da haka, shi ne riga quite mai tartsatsi ne.

A lokacin da zabi wani magani ko analog dole kwatanta su abun da ke ciki. Kamar yadda wani janar mulki, da kuma Generic equivalents ba idan aka kwatanta da juna - kawai asali. Alal misali, idan kana bukatar wani analog "cordarone" a ampoules, a wani yanki na wannan bayani ga allura ya kamata ba benzyl barasa, kamar yadda a cikin na asali "Cordarone."

Kamar yadda likitoci la'akari, ba na baya zuwa da kaddarorin da miyagun ƙwayoyi "Kordaron" analogues a Rasha gabatar da wani fairly manyan yawan kayayyakin, da suka hada da: "Ritmiodaron", "Sedakoron", "Amiokordin", "Kardiodaron", "Ritmorest", "Opakorden" "Amiodarone" daga daban-daban masana'antun ( "Amiodarone-Acre", "Vero Amiodarone" da kuma waɗansu da yawa). Su duk da wannan aiki sashi, amma iya daban-daban excipients. Da yawa daga cikinsu suna da yawa mai rahusa fiye da asali. A mafi yawan lokuta, wannan factor dogara a kan manufacturer. Alal misali, "Amiodarone", wanda aka mai suna guda a matsayin babbar abu dauke a cikin shirye-shiryen "Kordaron". Rasha analogue, kuma da farashin ne kusan sau uku ƙananan, ko da yake cikin siffar da saki, kuma da alamomi ga wannan manufa.

"Amiodoron" - mafi kyau analogues a Rasha. Shi ne kusan indistinguishable daga "cordarone" da kuma manufa na mataki, da kuma Hanyar aikace-aikace na da wannan high yi a kama fibrillation aukuwa da kuma rigakafin su aukuwa. Shedu game da shi ga mafi part m. Mutane da yawa daga cikinsu suka ce cewa "Amiodoron" Rasha samar taimaka wajen sauri kuma ba tare da nauyi pobochki.

Dosing da miyagun ƙwayoyi a ampoules

Kamar yadda aka ambata a sama, da mafita ga allura aka nuna domin saurin taimako na matsalar. tambaya "Kordaron" Allunan a wasu lokuta. Analogs aiki a cikin wannan hanya. A mafita aka allura ta catheter for 20-120 minti ko bolus akalla minti 3 a kashi na 5 MG da 1 kg jiki nauyi.

Dosing kwamfutar hannu "cordarone"

Da miyagun ƙwayoyi ne a dauka a kwaya a matakai biyu.

A mataki na farko, ko kaya lokaci: 600-800 MG da zarar kullum, da kara zuwa 10 g.

Mataki na biyu, ko gyara lokaci: 100-400 MG miyagun ƙwayoyi (tsawon ƙaddara da likita). A kalla kashi na 1200 MG da rana.

An yawan abin sama da miyagun ƙwayoyi ne m isa. Don hana shi, da mãsu haƙuri bada shawarar a san daidai da yadda za a dauki magani "Kordaron" umurci manual. Analogs, ciki har da m takwaransa a Rasha "Amiadaron", mafi yawansu ba su bayar da wannan bayyanar cututtuka na wani yawan abin sama.

Akwai alaka mai karfi bradycardia, ko da har zuwa wani sakamakon bugun zuciya. Idan shi ne ya sa ta kwamfutar hannu tsari, shi wajibi ne don wanke fitar da ciki da kuma daukar chelators. Kuma gudanar da sauran symptomatic magani, electrolyte balance ne gyara ba. Idan dole, ya kafa wata na'urar bugun zuciya.

Game da igiyar jini yawan abin sama bayanai ne bai cika ba. Aka bayyana rare lokuta na sinus bradycardia, tachycardia, sakamakon bugun zuciya. Jiyya ne kama da cewa nuna ga yawan abin sama lalacewa ta hanyar kwayoyi. Hemodialysis amiodarone kuma ta metabolites ba cire.

illa

Kamar yadda da wani ingantaccen hanyar m mataki, "Kordaron" "Amiodarone" da kuma sauran jerin analogs tsokane m events. Sun sa bradycardia up to sakamakon bugun zuciya, hawan jini, da wani mummunan sakamako a kan hanta, kamar haka ne, a wajen ban sha'awa jerin contraindications.

Daga kasa mai tsanani amma amma duk da haka m gefe-effects za a iya lura da ciwon kai da kuma dizziness, pleurisy, tari, da mãsu haƙuri iya kai ƙarar wani rauni, asarar gani acuity. Na iya haifar da rashin lafiyan halayen. A wannan matsala za a iya samu ta hanyar shan wani analog. "Kordaron" da sauran kwayoyi amiodarone Allunan domin wannan dalilin, ana sayar a Pharmacy kawai ta sayen magani. A bayani ga allura da aka yi amfani da kawai a wani asibiti yanayi.

Duk da haka, tare da kula dauka a zabi matsakaicin kashi illa an bayyana dan kadan ko maiyuwa bazai bayyana ba a duk. Kamar yadda muka gani a cikin wata mujalla "kordaron" da "Amiodarone" marasa lafiya shan wadannan kwayoyi, pobochka yawanci rauni, sauƙi shafe ta da daidaituwa da miyagun ƙwayoyi kashi.

contraindications

Tun amiodarone - mai kyawawan m miyagun ƙwayoyi, shi ne ba abin mamaki ba cewa shi ba zai iya kawai taimaka wajen inganta bayyana a cikin da dama zuciya matsaloli, amma a lokaci guda da ciwon a yankunan da sakamako a kan sauran gabobin ko da yanayin worsens tare da wasu concomitant cututtuka. Don kauce wa hadarin, ba da shawarar far tare da wannan magani a wasu lokuta.

Akwai wani fanni na yanayin da aka haramta daga karbar "Kordaron", "Amiodarone" da kuma sauran takwarorinsu a cikin alluna. Na farko shi ne wasu mahaukaci da yanayin zuciyar - sinus bradycardia, atrioventricular block tsanani digiri, hypotension, da tsawaita na QT tazara a kan ECG. Yana ba za a iya amfani idan haƙuri aka saukar a cikin jiki abun ciki na potassium da magnesium.

Contraindications hada thyroid cuta, kazalika da ciki da kuma nono - dalilin da aidin, wanda yana dauke da miyagun ƙwayoyi "Cordarone." Analog, ba dauke da shi, za a iya dauka kawai a kan likita na shawara.

Marasa lafiya a cikin tsofaffi bada shawarar cewa taka tsantsan a dauka a matsayin "Kordaron" da "Amiodarone" da sauran analogs. Marasa lafiya matasa, fiye da shekaru 18, wadannan magunguna ba su nada.

Kada sanya wata hanya ga wadanda suka sha wahala daga Bronchial asma, numfashi gazawar, ya bayyana zuciya rashin cin nasara. Mai tsananin cutar hanta da koda - ma wani dalilin to ki lura da wannan hanya.

Lalle, kada mu dauki da miyagun ƙwayoyi idan akwai wani mutum rashin ha} uri ga gyara daga cikin miyagun ƙwayoyi "Cordarone." Analogues a Rasha da kuma sauran kasashen Turai da guda abun da ke ciki, don haka a cikin wannan harka don maye gurbin daya sauran wakili ne mai wuya ga nasara.

Game da injections, ba za su iya yin jariran karkashin shekaru 3 da haihuwa, yara girmi shekaru 3, da kashi kada wuce 5 MG / kg. Kada Mix da miyagun ƙwayoyi a cikin wannan sirinji tare da wasu kwayoyi. A general, contraindications zuwa wani bayani kama da contraindications zuwa Allunan. Wannan sinus bradycardia, marasa lafiya sinus ciwo mai tsanani da kuma madugu cuta, kamar yadda sinoatrial block zukãtansu, kuma paroxysmal na ramin zuciya tachycardia. A musamman, irin mamaki suna yiwu a lokacin da shan amiodarone a hade tare da wasu kwayoyi.

Rubũta injections a lokacin daukar ciki mai yiwuwa ne kawai a na kwarai lokuta, a lokacin da lactation ne mai Hanyar magani ne gaba daya cire. Ba shi yiwuwa a gudanar far amfani da "cordarone" bayani tare da thyroid tabarbarewa, rashin lafiyan halayen ga aidin ko amiodarone.

Hulda da sauran kwayoyi

"Kordaron" za a iya hade tare da sauran kwayoyi. Saboda haka, ta antianginal sakamako ne inganta a hade tare da nitrate kwayoyi tsawo mataki. Yana za a iya amfani a tare da anticoagulants, diuretics, cardiotonic kwayoyi, ba mu'amala da, bi da bi, kada ku yi rauni, ko kuma karfafa sakamakon kowane "Kordaron" da kuma wasu sauran neuroleptics, analgesics, hypnotics da sedatives. Kusan kamar yadda m to wadannan kwayoyi wani analog.

"Kordaron" ba za a iya amfani da lokaci guda tare da Mao hanawa da kuma beta-blockers (a cikin kwarai lokuta kawai).

Kariya ga zalunta "kordaron" da "Amiodarone"

A lokacin liyafar daga wadannan nufin bukatar kula da jiki yanayin kafin magani, a lokacin da kuma bayan shi.

Kafin da kuma a lokacin far kwamfutar hannu tsari riƙe ECG bada shawarar. Effect da miyagun ƙwayoyi sa canje-canje a cikin electrocardiogram, musamman, da tsawaita na tazara T kuma Q-Q-T. Wadannan sakamakon na jarrabawa likita iya daidaita da sashi da kuma ƙayyade da tasiri na magani.

Jiyya da aka kare a lokacin tasowa atrioventricular block II kuma III digiri sinoatrialnaya, intraventricular biyu-masaƙa.

Tun da daya daga cikin aka gyara daga cikin miyagun ƙwayoyi ne aidin, na bukatar yau da kullum saka idanu na thyroid ayyuka. Kafin jiyya wajibi ne domin sanin da matakin na hormones T3, T4 da TSH. Lura cewa a kan bango na "cordarone" na thyroid radioisotope nazarin iya zama unreliable. A hormone matakan aidin ba zai tasiri a data.

Wani muhimmin factor ne domin sanin da matakin na potassium a cikin jini magani kafin magani da kuma a lokacin da shi.

Lokacin gudanar da "cordarone" shawarar igiyar jini jiko kawai, kuma ba a sirinji allura. In ba haka ba, watakila da ci gaban hemodynamic cuta - jijiya hypotension, m zuciya da jijiyoyin jini insufficiency. Sirinji allurar da miyagun ƙwayoyi ne kawai a na kwarai gaggawa yanayi da in babu sauran yiwuwa. A wannan yanayin da kashi ne 5 MG / kg da aka samu ga minti uku, re - ba jima fiye da minti 15 bayan na farko da gwamnatin. A hanya za a iya za'ayi kawai a cikin jijiyoyin zuciya kula sassan karkashin kulawa da ECG. "Kordaron" ba za a gauraye a wani sirinji tare da wasu kwayoyi. Idan ka yi dogon lokacin da magani ake bukata don zuwa jiko. Duk wani igiyar jini amiodarone za'ayi a asibitoci.

Idan haƙuri za a general m, da anesthetist ya kamata a rika cewa shan wannan magani.

Don kauce wa illa, marasa lafiya ya kamata a bi da wajabta sashi na likita.

A lokacin jiyya, marasa lafiya dole ne kauce wa yin amfani da hasken rana da kuma kariya game da shi (ciki har da musamman creams), idan ya cancanta.

Tabbata magana tare da likita, idan saboda wasu dalilai ba su so su dauki "Kordaron" da takwaransa. "Kordaron" da kuma irin kwayoyi tare da shi, kamar wani cardiac kwayoyi na iya zama hadarin gaske musamman idan uncontrolled liyafar. Kawai wani likita zai iya sanin abin da magani zai zama mafi kyau a cikin hali da kuma za su zabi wani hadari, amma tasiri sashi.