Abin da "Lyrics" kwamfutar hannu? A amfani da farashin

Medicine "lyrics" (Allunan), da farashin da yake daga 700 zuwa 4000 rubles., - isasshe sanannun miyagun ƙwayoyi. Active abu - pregabalin - analog na gamma-aminobutyric (Gaba) acid (Gaba). Daga baya a cikin labarin, za a ba annotation zuwa magunguna. Bari mu gano abin da kwayoyi "Lyrics" yin amfani da marasa lafiya.

inji na mataki

Pregabalin farfado da inganci da magani daga m neuropathy da postherpetic neuralgia, ga abin da kwayoyi "lyrics" wajabta rate up to 13 makonni da kullum ci rate 2 sau da har zuwa 8 makonni, 3 sau a rana. Kan bango na da ci gaban da nufin nuna wannan illa. Dangantawa da fibromyalgia ne a fili a bayyane raguwa a zafi bayyanar cututtuka batu yayin da shan miyagun ƙwayoyi allurai 300-600 MG da rana. Daily sashi na 450 MG da 600 MG za a iya kwatanta ga yadda ya dace, amma karshen ne kasa da jure. Da miyagun ƙwayoyi rage tsananin farfadiya seizures, wanda Allunan "lyrics" bayar da shawarar a hanya na 12 makonni, 2 ko sau 3 a kowace rana. A lokacin liyafar auku guda juna na illa da kuma tasiri na da miyagun ƙwayoyi a wannan kashi. kãmun mita fara rage riga a farko makonni na magani. Symptomatology na jimlace tashin hankali cuta nuna hali ya rage a farkon kwanaki bakwai na magani. Bayan makonni takwas 52% na miyagun ƙwayoyi marasa lafiya samun pregabalin da kuma 38% na marasa lafiya samun placebo, nuna wani kashi 50 cikin raguwa a cututtuka na Hamilton sikelin (HAM-A).

Pharmacokinetics

A medicament "lyrics" (kwamfutar hannu) - User ya tabbatar da wannan - a bada shawarar kullum allurai da gefen pharmacokinetic halin linearity, low (<20%) interindividual canzawa. Maimaita aikace-aikace na pharmacokinetics da miyagun ƙwayoyi za a iya annabta a kan tushen da wani naúrar na sashi data. Saboda haka a kai a kai saka idanu da taro na aiki sashi ba lallai ba ne. Pharmacokinetic sigogi na miyagun ƙwayoyi "Lyrics" a lafiya masu taimako, marasa lafiya da epilepsy da suka sami antiepileptic far, kazalika da samun da miyagun ƙwayoyi domin suppressing zafi syndromes ne irin wannan.

Absorption da kuma kawar

Bayan shan a kan komai a ciki pregabalin da ake tunawa da sauri sosai. Sa'a daya daga baya, da jini Cmax cimma a matsayin lokacin da ake ji a karon farko, kuma tare da maimaita. A kan bango na pregabalin baka bioavailability ne a ≥90% kuma shi ne mai zaman kanta da kashi. Ma'auni aka samu a lokacin da shan maimaita ta a cikin wani lokaci na 24-48 hours. Idan da miyagun ƙwayoyi ne amfani bayan wani abinci, da Cmax iya rage by 25-30% da kuma ƙara da nasara lokaci zuwa awa 2.5. Duk da haka, babu asibiti gagarumin sakamako a kan sha da miyagun ƙwayoyi ba da abinci. M da miyagun ƙwayoyi excreted da kodan canzawa. T1 / 2 talakawan of 6.3 hours.

Pharmacokinetics a lokuta na musamman

Idan ka damuwa na koda aiki, wajibi ne a yi la'akari da peculiarity na pregabalin yarda, shi ne kai tsaye na gwargwado ga creatinine yarda. M da miyagun ƙwayoyi excreted da kodan, saboda haka wajibi ne a hali na take hakkin su da ayyuka don rage kashi. Baya daga kodan, da medicament za a iya yadda ya kamata cire daga jini da hemodialysis (4-hour hemodialysis zaman bada 50% karu a da miyagun ƙwayoyi taro a jini) sa'an nan mafi kyawawa saduwa miyagun ƙwayoyi kashi. A musamman nazarin pharmacokinetics na jamiái "Lyrics" a marasa lafiya tare da mai illa hanta aiki ba a gudanar.

Pregabalin metabolized kusan ba fallasa, an nuna tare da fitsari a cikin canzawa tsari, duk da haka sosai hanta aiki ba muhimmanci shafi maida hankali da miyagun ƙwayoyi a jini. Lokacin da miyagun ƙwayoyi da aka bai wa marasa lafiya a kan shekaru 65 na shekaru, dole ne ka tuna cewa da shekaru Pregabalin yarda o ƙarin tabbatar da raguwa. Idan wani tsofaffi mutum na rage koda aiki, shi wajibi ne raguwa a magani wajabta kashi.

sashi

A kullum adadin shiri a tsare a cikin 150-600 MG da rana. Kudin shiga ne da za'ayi sau biyu ko sau uku, ko da kuwa da abinci. A medicament "lyrics" (Allunan) umurci manual bada shawarar shan tare da neuropathic zafi a 150 MG da rana. Idan cimma sakamako da kuma tolerability m daya mako kullum kashi iya karu zuwa 300 MG (designate "lyrics 300" Allunan). Idan dole, matsakaicin kashi na 600 MG da rana iya gudanar mako guda daga baya. Hakazalika lasafta kashi a lura da epilepsy. Kamar yadda aka ambata a sama, shi shawarar miyagun ƙwayoyi domin lura da fibromyalgia, wanda Allunan "lyrics" da aka gudanar a wani kashi na 75 MG da rana a cikin biyu allurai. A kara da kashi 300 MG shafar cimma sakamako da kuma tolerability. Idan babu kyau sakamako, kara da kashi zuwa 450 MG, kuma idan da ake bukata - daya mako zuwa 600 MG. Bi da kowa yana da tashin hankali cuta fara da kashi na 150 MG. Har ila yau, a mako, lura da cimma sakamako da kuma tolerability, da kullum kashi karu zuwa 450 MG, kuma bayan kwanaki 7 - har zuwa 600 MG (idan ya cancanta).

kau da miyagun ƙwayoyi

Idan dole, magani an daina bada shawarar a yi shi a kalla a mako mai sauka a hankali raguwa a kashi. Marasa lafiya da suke yi sosai koda aiki, da za'ayi mutum zabin da allurai. A taron na illa a marasa lafiya samun nufin "Lyrics" kwaya-equivalents ance da gwani. Daga cikin mafi kowa nufin da irin wannan sakamako za a iya ambata kwayoyi "Mydocalm" "Apizartron" "Sedavit" "Ambene".

shaidar

Magani bada shawarar domin kawar da neuropathic zafi, kamar yadda adjunctive far ga m seizures na epilepsy, cewa suna tare ko ba tare da sakandare hakan. Yana nufin nuna ga tashin hankali cuta jimlace yanayi, kazalika da fibromyalgia.

contraindications

Babu bayanai a kan yin amfani da miyagun ƙwayoyi a yara da kuma matasa har zuwa shekaru 17 har zuwa. A dangane da wannan magani da ake sa kawai zuwa manya. Contraindications hada hereditary cututtuka kamar galactose rashin ha} uri, lactase rashi, kazalika da malabsorption na glucose / galactose. A kayan aiki ba a nuna domin hypersensitivity. Don kula da m amfani da miyagun ƙwayoyi a marasa lafiya tare da na koda da zuciya rashin cin nasara.

illa

Bisa ga kwarewa da na asibiti aikace-aikace na medicament, a alama drowsiness da juwa kamar yadda a ke so sakamakon. Wadannan mamaki ayan faruwa a matsakaici ko m mataki. Daga cikin sauran illa sa a an daina miyagun ƙwayoyi jiyya, ya kamata a lura asthenia, da ruɗewa, Heart hangen nesa, incoordination, ataxia, na gefe edema. Har ila yau daga cikin illar lura da ciwon kai, asarar sani, seizures, kumburi na harshe, zawo, tashin zuciya, keratitis. Wuya da itchy fata da kuma angioneurotic dauki. Akwai urinary riƙewa, na huhu edema da gynecomastia. Daga cikin sauran illa aka kira gajiya.