"Alendronic acid": umarnin don amfani, analogs, reviews

Wanne bukatar "Alendronic acid"? Amsar wannan likita batun, za ka koya daga cikin kayan da wannan labarin. Bugu da kari, za mu gaya muku game da yadda za a dauki magani, a cikin abin da lokuta shi ne ba kyawawa don amfani, kuma idan suna da wani illa. Za ka kuma koyi game da tsari a cikin abin da muka duba yiwuwar samuwa ne wajen, ko yana da takwarorinsu cewa marasa lafiya magana game da shi.

A abun da ke ciki na miyagun ƙwayoyi da ta saki tsari da kuma marufi

"Alendronic acid", ko abin da ake kira miyagun ƙwayoyi "Alendronate", da aka kasuwanci a cikin nau'i na fari zagaye Allunan. The aiki sashi daga cikin miyagun ƙwayoyi ne alendronate sodium trihydrate, ko alendronic acid.

Amma ga ƙarin abubuwa, da aiki da miyagun ƙwayoyi qunshi wadannan: monohydrate, povidone, microcrystalline cellulose, croscarmellose sodium da kuma magnesium stearate.

A Pharmacy "Alendronic acid" da za a iya samu a cikin blisters 4 Allunan kowane.

A pharmacological kaddarorin da miyagun ƙwayoyi

Mene ne wani "Alendronic acid"? Guide shiri na samar da cewa kayan aiki ne da wani hanawa daga kashi resorption. Ginshikai na mataki na wannan magani da ake dangantawa da wata rage a cikin ayyuka na osteoclasts. Ya progressively qara yawa (ma'adinai) kashi nama, kazalika da bayar da tasu gudunmuwar da samuwar.

A pharmacokinetics da miyagun ƙwayoyi

Ta yaya tunawa "Alendronic acid"? Umurnai na yin amfani da wannan magani ya ƙunshi bayanin cewa a lokacin da gudanar a kan komai a ciki (2 hours kafin karin kumallo), a wani sashi na 70 MG bioavailability na aiki kashi a cikin mafi kyau jima'i ne game da 0,65%, da kuma karfi da kasa - game da 0.6%.

Idan ka dauki magani ga rabin sa'a ko awa daya kafin a ci abinci, shi muhimmanci rage-rage na bioavailability (har zuwa 0,45% da kuma 0.4%, bi da bi).

Yarda da miyagun ƙwayoyi a cikin 2 hours bayan cin abinci ba zai tasiri a bioavailability. Duk da haka, bayan amfani da kofi da kuma orange ruwan 'ya'yan itace rage bioavailability da kimanin 60%.

Dauri na aiki sashi daga cikin miyagun ƙwayoyi da jini da sunadarai ne kamar 78%.

Bayan samun farko medicament an rarraba ne a taushi tsokoki, kashi sa'an nan, inda, a gaskiya, shi ne ta kam, kodan da sauran.

A taro na miyagun ƙwayoyi a jini yana nufin bayan samun warkewa kashi ne a kasa da ji iyakace (kasa da 5 ng / ml).

A medicament ne biotransformation. Ya aka excreted daga jiki canzawa. A shirye-shiryen da aka halin da m karu a jini taro, da kuma wani sosai jinkirin saki na kashi nama.

Alamomi ga yin amfani da Allunan

Yanzu ka san abin da a "Alendronic acid". Me ya sa muke bukatar wannan kayan aiki? Bisa ga a haɗe umarnin, da miyagun ƙwayoyi yana da wadannan alamomi:

• osteoporosis a cikin mafi kyau jima'i a postmenopausal mata (kamar yadda wani rigakafin kashi samu karaya, ciki har da kashin baya, kuma kwatangwalo).
• osteoporosis a cikin karfi jima'i.
• Osteoporosis, wanda aka sa ta shafe tsawon amfani da glucocorticoid jamiái.
• Paget ta cutar.

"Alendronic acid": contraindications ga yin amfani da

A lokacin da muke la'akari da miyagun ƙwayoyi ba za a iya amfani? Umurnai na yin amfani da miyagun ƙwayoyi ya furta cewa, wannan magani yana da wadannan contraindications:

• hypocalcemia.
• Karuwan haƙuri medicament ji na ƙwarai to abubuwa.
• rashin iyawa na haƙuri ne a wani mike matsayi (a zaune har mike ko tsaya) for rabin awa.
• tsanani da cuta a cikin ma'adinai metabolism.
• tsanani na koda gazawar.
• hypoparathyroidism nauyi.
• esophageal stricture ko achalasia kazalika da sauran yanayin da haifar da toshewa da esophagus abinci.
• glucose-galactose malabsorption, lactase kasawa ko lactose rashin ha} uri .
• lactation.
• Alli malabsorption.
• ciki;
• yara shekaru.

M shan magani

A wasu lokuta, "Alendronic acid" da ake sa tare da taka tsantsan? A karkashin tsauraran likita dubawa ya zama cewa category na marasa lafiya, wanda shi ne wani karkacewa a cikin narkewa kamar fili (misali, irin ailments kamar yadda esophagitis, dysphagia, duodenitis, gastritis, peptic miki cutar 12 duodenal miki da ciki). Bugu da kari, da miyagun ƙwayoyi ya kamata ya kasance tare da matsananci hankali a marasa lafiya tare da wani rashi na bitamin D.

"Alendronic acid": umarnin don amfani da miyagun ƙwayoyi

Medicament "Alendronate" Ya kamata a dauki kawai da baki a wani adadin 1 kwamfutar hannu. Lokacin da wannan magani ba da shawarar tauna, ko soke. Ya Take azumi ga 2 hours kafin karin kumallo (a kalla rabin sa'a kafin na farko kashi na abinci, da ruwa, ko wasu na'urorin lafiya).

Da miyagun ƙwayoyi dole sha bayyana ruwa. Wannan shi ne saboda cewa wasu abubuwan sha (misali, ruwan kwalba, shayi, kofi, orange ruwan 'ya'yan itace) markedly rage sha na aiki abu.

Da shawarar sashi na medicament ne 1 kwamfutar hannu (ko 10 MG) da rana da zarar ciki. A wasu lokuta, likitoci wani kashi gudanar zuwa haƙuri, wanda shi ne kamar haka: 1 kwamfutar hannu (ko 70 MG), 1 lokaci na mako daya.

Domin lura da osteoporosis a maza da mata (a postmenopausal mata), kazalika da osteoporosis, wanda aka sa ta shafe tsawon amfani da glucocorticoid jamiái, da miyagun ƙwayoyi ne riƙi ta 10 MG kullum ko 70 MG sau ɗaya a mako.

Tare da wannan rashin lafiya kamar yadda Paget ta cuta, dauke da mu da miyagun ƙwayoyi gudanar a wani sashi na 40 MG da rana. A tsawon lokaci da far ne 6 watanni.

Idan ka bazata miss shiri yanayin 1 da mako, da kwamfutar hannu da ya kamata a dauka a cikin safe gobe. An haramta amfani da magani a cikin adadin alluna biyu sau daya a rana.

Yawan abin sama da miyagun ƙwayoyi

Abin da ya faru idan haƙuri zama ba dama, ka dauki wannan hanyar a matsayin "Alendronic acid"? Shirye-shirye na irin wannan da bayyanar cututtuka na wani yawan abin sama kamar yadda hypophosphatemia, ƙwannafi, hypocalcemia, erosive da ulcerative raunuka na gastrointestinal fili, esophagitis, zawo.

A cikin hali na haƙuri gabatar da sakamakon da ya kamata a ba dukan madara ko alli-dauke da antacids. Wajibi ne ga nauyin da miyagun ƙwayoyi. A view of mafi hadarin tasowa esophageal mucosa hangula ba da shawarar a sa amai. A hali na yawan abin sama da mãsu haƙuri dole ne a karkata zuwa ga gaskiya matsayi.

Illa tasowa bayan samun medicament

Zai iya sa "Alendronic acid" korau sabon abu? Reviews da marasa lafiya da kuma likitoci sun ce da miyagun ƙwayoyi yana da wani gwada manyan yawan illa. Me daidai, mun duba kadan kara.

• Tsarin narkewa kamar: esophagitis, zawo, dysphagia, dyspepsia, ciki zafi, bloating, maƙarƙashiya, da kuma ƙwannafi. Quite wuya bayan dosing a marasa lafiya da ciwon amai da melena, tashin zuciya, esophageal stricture, gastritis, esophageal miki, miki pharynx kuma baka rami mucous membranes, esophageal miki perforation tare da zuwan zub da jini.
• Juyayi tsarin: ciwon kai.
• Musculoskeletal tsarin: ciwo a cikin tsokoki, kasusuwa da kuma gidajen abinci.
• Gabobin da hangen nesa: scleritis da uveitis.
• Alerji: edema angioedema, rash, Stevens-Johnson ciwo da mai guba epidermal necrolysis (a rare lokuta).
• Sauran gefen effects: erythema, rash, photodermatosis, itching da kuma symptomatic hypocalcemia. Akwai ma lokuta na osteonecrosis na ƙananan kuma babba muƙamuƙi a marasa lafiya tare da ciwon daji suka sha anticancer far da ya shafi yin amfani da bisphosphonates. Saboda haka, abin da ya faru na osteonecrosis hadarin dalilai sun hada da: jiyyar cutar sankara, da ciwon daji, magani da corticosteroids, radiation far, matalauta na baka tsabta, gida kamuwa da cuta, ko kumburi, ciki har da osteomyelitis.
• Laboratory gwaje-gwaje: dõgẽwa kuma kadan karu a taro na alli da phosphate.

Ba za mu iya ce cewa da hankula cututtuka a farkon miyagun ƙwayoyi far suna da wadannan: malaise, myalgia, da kuma zazzabi.

Hulda da sauran kwayoyi

Tare da wani kwayoyi ga marasa lafiya ba sananne "Alendronic acid", ta ma'ana?

Bisa ga wa'azi, shi ne bai dace da lokaci daya liyafar da kayan aiki tare da magunguna wanda dauke da alli a tsarin da kuma antacids (saboda wani yiwu rage sha na aiki miyagun ƙwayoyi abu).

A tazara tsakanin gwamnati da miyagun ƙwayoyi "Alendronate" da kuma yin amfani da sauran magani bukatar ya zama ba kasa da rabin awa.

Nonsteroidal jamiái, kazalika da acetylsalicylic acid iya muhimmanci ƙara da gefen sakamakon da miyagun ƙwayoyi a kan gastrointestinal fili gabobin.

Hada liyafar "alendronate" (amma ba duka biyu) tare da estrogen ba tare da wani canji na ayyuka da kuma ci gaban da wani illa.

A liyafar da irin wannan magani, a matsayin "prednisolone", ba tare da gagarumin canje-canje a bioavailability acid.

Musamman umarnin don samun wata na'urar kiwon lafiya da

Abin da ya kamata ka sani kafin ka fara samun wani kayan aiki irin su "Alendronic acid"? Analogs, kuma ya dauke da miyagun ƙwayoyi iya adversely shafi gastrointestinal gabobin. Saboda haka, don rage irritant sakamakon da magani bada shawarar a yi da safe a kan komai a ciki a gilashin ruwa.

Bayan karbar magunguna zama dole ga rabin sa'a a cikin wani mike matsayi. Amfani da kwance matsayi ko a lokacin kwanta barci kara hadarin irin wannan deflection kamar yadda esophagitis.

A haƙuri ya kamata a sanar da an daina miyagun ƙwayoyi a lokacin da ƙwannafi auku, da bayyanar zafi a cikin kirji da hadiya, kazalika da ci gaba da dysphagia.

Idan hypocalcemia kamata gudanar da gyara kafin a fara far. Haka kuma an bada shawarar a kashe disturbances na ma'adinai metabolism da kai ga wannan karkacewa.

A lokacin da yin amfani da bisphosphonates ga mãsu haƙuri kamata a tabbatar da ci daga isassahen na bitamin D da alli.

A lokacin far saboda tabbatacce sakamako a kan acid na da kashi ma'adinai yawa a cikin wani haƙuri iya samun wani kadan karu a taro na phosphate da alli a cikin jini.

Kafin jiyya da bisphosphonates a marasa lafiya tare da concomitant hadarin dalilai (tare da ciwon daji jurewa jiyyar cutar sankara, radiation far, da dai sauransu). Lalle ne haƙĩƙa, auku hakori jarrabawa.

Price da analogues da miyagun ƙwayoyi

Yanzu ka san yadda wannan miyagun ƙwayoyi ya kamata a dauka a matsayin "Alendronic acid". Menene wannan magani wajabta ta likita, mu ma samu ba. Duk da haka, mafi yawan marasa lafiya wanda aka wajabta wannan magani, ko da yaushe damu game da wannan tambaya: nawa ne kudin?

Yau "Alendronic acid" za a iya saya don 350 rubles (4 Allunan). Ganin dosing jadawalin (sau daya a sati), da farashin ba sosai high.

Idan kafin mu da magani ba ya dace ku ga wani dalili, shi za a iya maye gurbinsu da equivalents. Wadannan sun hada da kwayoyi kamar "Tevanat", "Ostalon", "Alendronate", "Strongos", "Alendrokern", "Ostealen", "Lindron", "Alental", "Foroza", "Osterepar ',' FOSAMAX "da sauransu.

Reviews da marasa lafiya da likitoci game da miyagun ƙwayoyi

Abin da yi marasa lafiya da likitoci game da wannan makaman a matsayin "Alendronic acid"? A cewar su martani, da miyagun ƙwayoyi copes tare da aiki. Wannan abu ne da Qarfafa kashi nama, ya bi osteoporosis da Paget ta cutar.

Duk da haka, ba shi yiwuwa ba a lura da cewa wannan magani yana da wani gwada manyan yawan illa. Saboda haka, da miyagun ƙwayoyi ya kamata a dauka kawai a kan nada masana. A karshen kamata ko da yaushe a sanar da haƙuri game da contraindications.

The most yawan korau sake dubawa a cikin adireshin "alendronic acid" ya zo daga marasa lafiya da suke da matsaloli tare da narkewa kamar fili. Wannan shi ne saboda a gaskiya wannan magani iya adversely shafi ciki, esophagus da hanjinsu.