Da miyagun ƙwayoyi "Lovastatin": umarnin don amfani, analogs, description, abun da ke ciki da kuma sake dubawa

Matsalar da high cholesterol damun mutane da yawa a jini. Wannan shi ne saboda a gaskiya wannan halin da ake ciki na iya haifar da wani matsalar aiki na samfur na zuciya da jijiyoyin bugun gini tsarin a matsayin dukan. Don kawar da hyperlipoproteinemia zama dole ba ne kawai don ci, amma kuma dauki wasu magunguna.

A mafi tasiri wajen rage cholesterol a cikin jini yana dauke su da wani magani "Lovastatin". Umarnin don amfani, price, reviews, analogs da contraindications da miyagun ƙwayoyi aka gabatar a kasa. Za ka kuma koyi abin da masana suka ce game da shi, kuma abin da sake dubawa bar ta masu amfani.

Form, abun da ke ciki, da kuma marufi bayanin miyagun ƙwayoyi

A medicament "Lovastatin" umurci manual wanda ake cushe a cikin wani kwali akwatin, an sayar a cikin nau'i na fari, zagaye Allunan. The aiki sashi daga cikin miyagun ƙwayoyi lovastatin abubuwa. Game da karin bijiro da batun kafa, sa'an nan suka hada da lactose monohydrate, sitaci, cellulose, ascorbic acid, butylated hydroxyanisole, citric acid da magnesium stearate.

Samuwa medicament na salon salula blisters kuma fakitoci na kwali bi da bi.

Ginshikai na mataki na miyagun ƙwayoyi

Mene ne manufa da mataki a cikin miyagun ƙwayoyi "Lovastatin"? Umarnin don amfani, m ruwaito cewa hanta-PL rabe gwada jini lipoproteins. Su fitarwa daga gare ta hanyar hulda da ce rabe. A sakamakon haka, da hanta Kwayoyin hada cholesterol.

The aiki manufa da miyagun ƙwayoyi a karkashin shawara saboda da danniya na 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Wannan enzyme, tare da taimako na wanda kira na cholesterol.

Rage samuwar cholesterol ya shafi wani compensatory karuwa a yawan LP-rabe a kan hepatocytes. A sakamakon irin wannan daukan hotuna accelerates kan aiwatar da cire daga jini low yawa lipoprotein, kazalika da rage total cholesterol, PL da cholesterol rage matsakaici yawa.

Features da miyagun ƙwayoyi

Abin da sauran kaddarorin ne "Lovastatin" kwamfutar hannu? Umurnai na amfani (price reviews aka gabatar a karshen cikin labarin) na nuna cewa wakili ne iya rage abubuwan da ke apolipoprotein B, da kuma triglycerides, kazalika da muhimmanci ƙara matakin high yawa lipoproteins.

A warkewa sakamako bayan gwamnati da miyagun ƙwayoyi aka bayyana a cikin makonni biyu, kuma matsakaicin - a game da wata daya da rabi. Duk da haka, ya rike for shida makonni bayan an daina miyagun ƙwayoyi.

Inganci a dogon lokacin da amfani ba rage. Ya kamata kuma a lura da cewa, an samar daga biocultures Aspergillus terreus da Monascus ruber.

sanadin motsi Properties

miyagun ƙwayoyi "Lovastatin" Har yaushe tunawa? Umurnai na amfani (da farashin da miyagun ƙwayoyi ne ba sosai high) ya bayar da hujjar cewa sha na da miyagun ƙwayoyi daga cikin gastrointestinal fili ne jinkirin. Haka kuma, shi rage kwayoyi a kan komai a ciki.

A bioavailability na wakili ne sosai low (game da 30% na kashi). Game da hudu aka samu cincirindo a cikin jini. Bayan wani m rana, kuma shi ne rage game da 10% na matsakaicin.

Dauke da wani magani ne 95% daure su jini sunadaran. Clearance da miyagun ƙwayoyi da guda kashi lura for 3 hours.

Mene ne magani "Lovastatin"? Umarnin don amfani da rahoton cewa wannan prodrug. Bayan na farko nassi ta hanyar hanta, ta zama aiki form.

Drug metabolized da isoenzymes. Its rabin rayuwa ne 180 minti. Magunguna aiki rabi da ta metabolites ake excreted ta hanyar da kodan da kuma hanjinsu.

Alamomi ga lozenges

A gaban wani yanayin haƙuri rubũta "Lovastatin" kwamfutar hannu? Umurnai na amfani (bayanin irin miyagun ƙwayoyi da aka gabatar a farkon labarin) rahoton cewa wannan kayan aiki ne sosai tasiri a farko hypercholesterolemia (hypolipoproteinaemias IIb da IIa irin) tare da babban abun ciki na LDL (idan abin da ake ci far ga mutanen da dagagge jijiyoyin zuciya atherosclerosis hadarin tabbatar da m) da kuma lokacin da a hade hypertriglyceridemia da hypercholesterolemia.

Ya kamata mu ma lura da cewa dauke da miyagun ƙwayoyi sau da yawa wajabta kuma atherosclerosis.

Contraindications zuwa sami prodrug

A wasu lokuta, da haƙuri ba da shawarar yin amfani da "Lovastatin" kwamfutar hannu? Umurnai na amfani (lura da wannan magani dole ne a gudanar da wani likita) rahoton cewa wakili ne contraindicated da aiki hanta cututtuka da kuma daukar ciki ko yiwuwa, kara transaminase aiki na unknown asalin, kazalika a lokacin da nono-ciyar, a mai tsanani haƙuri da yanayin (general), da kuma dagagge ji na ƙwarai to lovastatinu.

Har ila yau kyan gani, magani ake ba sananne a matsayin qananan, idan myopathy da cholestasis.

Shan magani da aka haramta a Hade da giya. Special kula da aka wajabta wa marasa lafiya bayan jijiyoyin zuciya jijiya kewaye tiyata.

Drug "Lovastatin": umarnin don amfani da

Price, analogues na wannan kayan aiki da za a tattauna a little kara.

Bisa ga umarnin, da kwamfutar hannu "Lovastatin" ya kamata a dauka a ciki a lokacin abincin dare sau daya a rana.

Tare da wannan pathological yanayin ne hyperlipidemia, wani magani da aka gudanar a wani adadin na 10-80 MG da zarar (da kashi dogara a kan mataki na cuta mai tsanani).

Jiyya dauke da miyagun ƙwayoyi fara da kananan allurai. Sa'an nan a hankali ya karu. A mafi kullum sashi daga cikin miyagun ƙwayoyi na 80 MG, za a iya gudanar da daya ko biyu a rana sau (safe da kuma lokacin kwanta barci). Selection na warkewa allurai ne da za'ayi tare da wani tazara daya watan.

Kamar yadda a cikin jijiyoyin zuciya atherosclerosis prescribers "Lovastatin"? Umurnai na amfani rahotanni cewa a irin wannan cuta medicament aka gudanar a wani kashi na 20-40 MG. Idan kayyade adadin medicament tabbatar da m, to, shi aka ƙara zuwa 60-80 MG.

Lokacin hade tare da fibrate miyagun ƙwayoyi ko niacin ta sashi kada ta kasance mafi girma fiye da 20 MG da rana.

m events

Shin da illa na magani, "Lovastatin"? Umurnai na amfani ce da wadannan m events:

• cataracts, ciwon kai.
• na gani atrophy, juwa ko jiri.
• rashin barci, barci cuta, juyayi, wani rauni, paresthesias.
• tsoka cramps, myalgia, myositis
• a cikin mutane da shan niacin, "Tacrolimus" ko "Gemfibrozil" ƙãra hadarin rhabdomyolysis.
• thrombocytopenia, hemolytic anemia.
• ƙwannafi, biliary cholestasis, tashin zuciya, hepatitis, flatulence, dandano da batattun, maƙarƙashiya, cholestatic jaundice, zawo.
• ya karu aiki na CPK da hanta transaminase.
• kara a bilirubin da alkaline phosphatase .
• Angioedema, rash, pruritus, arthralgia, urticaria.
• alopecia da kuma rage iko.

Yawan abin sama da miyagun ƙwayoyi

da haƙuri ba ya faruwa a bazuwar hakan allurai na magani musamman cututtuka.

A cikin kallo na pathological yanayi wanke da abin ya shafa ciki da kuma wajabta liyafar sorbents. Har ila yau, marasa lafiya underwent saka idanu na da harshen damo na hanta da kuma na ayyuka na creatine kinase.

miyagun ƙwayoyi interactions

A lokaci daya da yin amfani da manyan yawa na garehul ruwan 'ya'yan itace, kazalika da "gemfibrozil" da "fenofibrate" na taimaka wa mafi girma hadarin tasowa myopathy.

Karbar da miyagun ƙwayoyi da nicotinic acid "clarithromycin", "erythromycins", "Cyclosporins", antifungal kwayoyi ( "Itraconazole" "ketoconazole"), "nefazodone" da "Ritonavir" kaiwa zuwa wani karuwa a miyagun ƙwayoyi maida hankali a cikin jini, kazalika da lalata tsoka nama da kuma hadarin myopathy.

Co-gwamnati "Lovastatine" tare da "warfarin" na kara hadarin zub da jini.

Drug "Cholestyramine" rage bioavailability na wakili. Saboda haka, lokaci tazara tsakanin su ci ya kamata a kalla 2-4 hours.

takamaiman shawarwari

Tare da matsananci hankali miyagun ƙwayoyi "Lovastatin" wajabta wa mutane tare da wani tarihi na cutar hanta. Haka ya shafi kullum shan barasa.

Ya kamata kuma a lura da cewa override yana nufin a yanayin saukan wani m karuwa a hanta transaminases abinda ke ciki, ko kuma CPK.

A kudin da miyagun ƙwayoyi da kuma ta analogues

A halin yanzu, da sayan shawara magani a drugstores na Moscow da sauran Rasha birane ne ba zai yiwu. Idan dole, shi za a iya ba da umarnin via da World Wide Web. Prices a online Pharmacy bambanta sosai. Wannan magani ne samuwa a cikin kewayon 300-600 rubles.

Idan dole, la'akari da nufin za ka iya maye gurbin irin wannan kwayoyi a matsayin "Apekstatin", "Fluvastatin," "Cardiostatin", "Iinvastin", "Vero Lovastatin," "Pravastatin", "Holetar", "Lovasterol", "Mevacor" "Mevinakor", "Lovakor".

magani Reviews

Yanzu ka san abin da su ne waɗanda kwayoyi, kamar yadda "Lovastatin". Umurnai, abun da ke ciki, yin amfani da miyagun kwayoyi analogs cewa an bayyana a cikin wannan labarin.

A cewar kwararru, sia-ragewan kwayoyi amfani a lura, kazalika don rigakafin atherosclerosis da rikitarwa.

The aiki manufa da wannan magani ne don rage matakin na atherogenic lipoproteins a cikin jini

Bisa ga rahoton na likitoci, yanzu na tara quite mai yawa kwarewa da na asibiti da yin amfani da "Lovastatine". Shi ne daya daga cikin safest magunguna. Wannan magani yana da wani gwada da kyau-jure tsawon lokaci far.

A wani nazari da marasa lafiya sosai rare gunaguni na illa. Wani lokaci wannan magani zai iya sa flatulence, zawo, ciwon mara, maƙarƙashiya, rashin barci da kuma tsoka zafi. Yawanci, irin halayen bace a cikin makonni biyu bayan farko na far ko da sakamakon rage kashi.