"Gordoks": alamomi don amfani, contraindications, reviews

Mene ne magani "Gordoks"? Alamomi ga yin amfani da kayan aiki za a gabatar a kasa. Mu kuma gaya muku game da tsari a cikin abin da miyagun ƙwayoyi da aka saki, idan suna da wani contraindications, yadda ya kamata a yadda ya kamata amfani, abin da illa na iya faruwa bayan da aikace-aikace, da sauransu.

Saki nau'i na da miyagun ƙwayoyi, da kuma marufi abun da ke ciki

A abin da fom iya sayan magani "Gordoks"? Alamomi ga yin amfani da kayan aiki irin wannan cewa mafi yadda ya kamata kawai a lokacin da gudanar intravenously. Saboda haka, wannan magani ne kawai saki a 10 ml vials a cikin wani bayani.

The aiki bangaren na wakili ne aprotinin. Drug ma ya hada da karin aka gyara irin ruwa ga allura, benzyl barasa da kuma sodium chloride. Daya kartani akwatin ne 25 ampoules.

A pharmacological kaddarorin da miyagun ƙwayoyi

Me ya sa zan bukaci magani "Gordoks"? Alamomi ga yin amfani da wannan kayan aiki sun hada da cututtuka na narkewa kamar tsarin. The aiki miyagun ƙwayoyi bangaren yana da antiproteoliticheskoe, hemostatic da antifibrinolytic effects. Yana da tasiri a cikin cututtuka na pancreas. Bugu da ƙari, wannan magani ne iya markedly rage fibrinolytic aiki na jini. An sau da yawa wajabta a matsayin m far ga duk iri jihohin buga.

Ka'idar aiki na likitanci da wuraren

Mene ne magani "Gordoks"? Amfani a yara da kuma manya ya kamata a yi kawai a kan takardar sayen magani. Wannan shi ne saboda cewa da aiki miyagun ƙwayoyi ne an hanawa na proteolytic enzymes cewa yana da antifibrinolytic Properties.

Bayan samuwar stoichiometric gidaje reversible miyagun ƙwayoyi aiki abu damuarn aiki na nama da jini kallikrein, plasmin da trypsin. A sakamakon irin wannan daukan hotuna an rage fibrinolytic aiki na jini.

Bayan haka, aprotinin ne iya kunna lamba lokaci na coagulation to hana da yawa shiga tsakani attenuate kumburi martani, Munã rage thrombin tsara da kuma fibrinolysis.

Abin da amfani da magani "Gordoks"? Alamu sun hada da m baki. Ta hanyar wannan yana nufin rage yawan jini da asarar da kuma bukatar for transfussion.

Pharmacokinetics da miyagun ƙwayoyi

Yadda azumi addashin miyagun ƙwayoyi "Gordoks"? A amfani a dabbobi magani da kuma far nuna cewa bayan igiyar jini gwamnati na aiki sashi maida hankali a cikin jini sosai da sauri rage-rage saboda da miyagun ƙwayoyi rarraba a cikin extracellular sarari. A farko rabin-rai da miyagun ƙwayoyi ne lura a 0.4-0.8 sa'o'i da karshe - bayan 5-10 hours.

Communication jini gina jiki ne 80%.

Aprotinin sun fi mayar da accumulates a kodan, da kuma wani karami - a cikin guringuntsi nama. A jari na miyagun ƙwayoyi a cikin kodan ne da za'ayi saboda ta dauri ga epithelial sel na koda tubules. Kamar yadda na jari a cikin tsokoki na guringuntsi, wannan ne saboda da dangantaka da aprotinin, wanda shi ne, a gaskiya, shi ne tushe.

Jari na aiki sashi daga cikin miyagun ƙwayoyi a sauran gabobin idan aka kwatanta da ta maida hankali a jini. The mafi ƙasƙanci kashi da aka samu a cikin kwakwalwa. Ya kamata kuma a lura cewa wata iyaka adadin aprotinin iya shiga ta hanyar da placental shãmaki.

Active miyagun ƙwayoyi bangaren metabolized a koda (lysosomal enzymes) to m metabolites. A kananan adadin aprotinin a fitsari fitarwa.

Da miyagun ƙwayoyi "Gordoks": alamomi ga yin amfani da

Reviews game da wannan kayan aiki, za mu gabatar a kasa. Game da wannan labarin sashe, to, shi so in gaya maka game da abin da aka dauke da wani magani wajabta wa marasa lafiya.

Saboda haka, alamomi ga yin amfani da wannan magani ana da wadannan pathological yanayi:

• a kullum pancreatitis (miyagun ƙwayoyi amfani a m dakwai, komowan cutar, kazalika da a tsanani cuta).
• pancreatitis a m siffar (a magani amfani ne kawai a cikin hadaddun far).
• pancreatitis, wanda ci gaba a sakamakon raunin da ya faru ko m hanyoyin.
• pancreatic.
• sa hannu na jini da ya faru a kan backdrop na hyperfibrinolysis (bayan tiyata, da dama raunuka, bayan isar da kafin su, a lokacin da polimenoree).
• a matsayin m gwargwado nonspecific postoperative mumps.
• angioneurotic edema.
• bincike da gwaje-gwaje a kan pancreas, da kuma tiyata.
• ãyõyin buga (msl, mai guba, traumatic ko hemorrhagic).
• Daban-daban nama rauni (m da kuma zurfin).

Me har yanzu amfani da miyagun ƙwayoyi "Gordoks"? Alamomi ga yin amfani hada da, da kuma irin sabawa matsayin coagulopathy, a lokacin da akwai azãba mai tsanani zub da jini da kuma sakandare hyperfibrinolysis (as adjuvant far).

Ba za mu iya ce cewa wannan kayan aiki ne rayayye gudanar for prophylactic lura da zub da jini bayan tiyata da na huhu embolism.

Contraindications ga yin amfani da wannan magani

A wasu lokuta, ba za ka iya amfani da miyagun ƙwayoyi "Gordoks"? Aikace-aikace na pancreatitis ya auku fiye da sau da yawa, wannan shi ne babban nuni. Game da contraindications, sa'an nan su ne kamar haka:

• hypersensitivity na haƙuri ko karfi furta rashin lafiyan halayen ga aiki miyagun ƙwayoyi abu (Ina nufin aprotinin).
• na farko da na uku awo na ciki.
• a lokacin shayarwa.

Ya kamata kuma a lura da cewa da miyagun ƙwayoyi a tambaya dole ne a yi amfani da taka tsantsan a lokacin sakamakon bugun zuciya, saboda da ƙãra hadarin na koda gazawar, zurfin hypothermia, kazalika da alerji (bayan baya far aprotinin).

Drug "Gordoks": umarnin don amfani da

Pancreatitis, kazalika da sauran alamomi da miyagun ƙwayoyi ne gudanar sannu a hankali intravenously. Matsakaicin kudi na Drug Administration ya kamata game da 5-10 ml da minti.

A lokacin da jiko na miyagun ƙwayoyi da haƙuri ya zama kawai a cikin supine matsayi. Da miyagun ƙwayoyi da bukata kawai a gudanar ta hanyar a jijiya kashin. Kuma amfani da su don gabatar da wasu nufin shi ne tsananin haramta.

Ganin cewa bayan yin amfani da medicament ne wani babban hadarin anaphylactic da kuma rashin lafiyan halayen a dukan marasa lafiya a cikin minti 10 kafin gwamnati na babban dosing ake bukata don shigar da gwajin girma wanda shi ne 1 ml (ko 10 dubu. KIU). Idan bayan da cewa babu wata matsala ba a bi, sa'an nan gudanar da wani warkewa kashi na miyagun ƙwayoyi.

Ya kamata kuma a lura da cewa, zai yiwu amfani da histamine blockers H1- da H2-tsoka mai amsa sigina na ¼ hour kafin jiko na miyagun ƙwayoyi. A cikin wani hali, shi dole ne dole a bayar da duk na misali gaggawa matakan da ake nufi ga lura da rashin lafiyan ko anaphylactic dauki.

Manya bayar da shawarar dauke da miyagun ƙwayoyi gudanar intravenously a wani na farko kashi wanda 1-2 miliyan. KIU. Shin, shi sannu a hankali, a kan kwata na sa'a guda bayan da farko na maganin sa barci da kuma kafin sternotomy.

Bayan kammala bolus jiko na miyagun ƙwayoyi zuwa haƙuri sa (a wani kudi na 250-500 dubu. KIU awa) zuwa ƙulli aiki. A total adadin aprotinin gudanar a lokacin da dukan shakka, dole ne ba zama ya fi miliyan 7 KIU.

Mutane da illa koda aiki, kazalika da tsofaffi da marasa lafiya sashi gyara ake bukata.

Gefen sakamakon wannan magani

Mene ne gefen sakamakon wani miyagun ƙwayoyi "Gordoks" alamomi, contraindications wanda aka bayyana a sama?

Kamar yadda yi nuna, marasa lafiya samun aprotinin karo na farko, kada su tsoma baki tare da ci gaban anaphylactic ko rashin lafiyan halayen. Kamar yadda na sake gwamnati da miyagun ƙwayoyi, da mita na illa ya karu zuwa 5%. Wannan Gaskiya ne, a cikin akwati inda irin wannan amfani da miyagun ƙwayoyi da aka za'ayi domin 6 watanni.

Lokacin da reusing nufin fiye da watanni 6, a yiwu hadarin anaphylactic da kuma rashin lafiyan halayen ne game da 0.9%.

A hadarin mai tsanani illa ne ƙwarai ya karu a yayin da cewa for rabin shekara, aprotinin aka yi amfani da fiye da sau biyu.

Lokacin da reusing shiri na wani alamu na rashin lafiyan halayen aka lura, da m aikace-aikace na magani iya quite iya kai wa ga ci gaban da a ke so mamaki, ko m.

Alamun anaphylactic da kuma rashin lafiyan halayen bayan yin amfani da miyagun ƙwayoyi May bayyananne kansa a matsayin wani iri-iri cuta na narkewa kamar fili, da zuciya da jijiyoyin jini da kuma na numfashi tsarin, kazalika da fata.

A cikin hali na gefen effects, da yin amfani da miyagun ƙwayoyi ya kamata a nan da nan soke. Shi ne kuma wajibi ne don tabbatar da cewa duk daidaitaccen gaggawa matakan (misali, jiko far, gwamnati na epinephrine, epinephrine, corticosteroids).

To, abin da suke da maras so effects faruwa bayan yin amfani da "Gordoks" miyagun ƙwayoyi? Aikace-aikace a ophthalmology, ciki magani, da kuma dabbobi magani zai iya sa bayyanar da wadannan munanan:

• Alerji: anaphylaxis, anaphylactic da kuma rashin lafiyan halayen, anaphylactic buga (yiwu m).
• Zuciya da jijiyoyin jini tsarin: thrombosis, ischemia, pericardial effusion, tsokar zuciya infarction, thrombosis ko occlusion na jijiyoyin zuciya arteries, na huhu embolism da jijiya thrombosis, wanda zai iya faruwa da cuta daga cikin muhimmanci gabobin kamar huhu, kodan da kuma kwakwalwa.
• hematopoietic tsarin: coagulopathy, ciki har da DIC.
• Urinary tsarin: take hakkin koda aiki da koda gazawar.
• Local m halayen: thrombophlebitis, dauki a jiko ko allura.

Specific umarnin don amfani da miyagun ƙwayoyi

Yanzu ka san yadda wani likita makaman kamata a yi amfani a matsayin "Gordoks". Umarnin don amfani a pancreatitis da kuma sauran cututtuka da aka nuna kawai a sama. Duk da haka, kafin magani tare da wannan magani bada shawarar gudanar da gwaje-gwaje fata ake bukata don taimaka wani mutum domin sanin mutum ji na ƙwarai da aiki sashi jamiái (Ina nufin aprotinin).

Idan wani tarihi na rashin lafiyan halayen da aka kayyade, sa'an nan kafin lura da haƙuri kamata dauki corticosteroids da histamine H1 tsoka mai amsa sigina blockers.

A lokacin da irin sabawa matsayin hyperfibrinolysis da DIC, da miyagun ƙwayoyi ya kamata a yi amfani ne kawai bayan da data mamaki, za a shafe ta. Haka ya shafi a lokuta inda haƙuri yana da wani m sakamako na heparin.

Sosai a hankali dauke da miyagun ƙwayoyi An wajabta wa waɗanda marasa lafiya da suke ga 'yan kwanaki kafin a fara far samu tsoka relaxants.

Kamar yadda wani ɓangare na miyagun ƙwayoyi "Gordoks" yana benzyl barasa. A wannan batun, ta iyaka girma da rana kada wuce 90 MG da kg jiki nauyi.

Medicament "Gordoks" ba a canza irin wannan kwayoyi a matsayin "heparin".

Da zarar vial da aka bude tare da bayani, ya kamata a yi amfani da nan da nan. A lokacin sake amfani da miyagun ƙwayoyi a tafiyad da miyagun ƙwayoyi daga wani bude akwati da aka haramta.

Yana da matuƙar ba a ke so zuwa Mix da magani "Gordoks" da sauran magunguna.

Shin yana yiwuwa a gabatar da miyagun ƙwayoyi Pet?

Shin ya halatta a shigar da karnuka da Cats miyagun ƙwayoyi "Gordoks"? The yin amfani da izini a dabbobi. Duk da haka, da sashi daga cikin miyagun ƙwayoyi kamata kawai ayyana wani likitan dabbobi, da kuma kawai bayan da duban dan tayi jarrabawa na kogon ciki na wani Pet.

Yadda za a shigar da "Gordoks"? A amfani da bala'in, da miyagun ƙwayoyi ya zama musamman da hankali. Wannan shi ne saboda cewa da miyagun ƙwayoyi ne dauke allergenic.

Da miyagun ƙwayoyi ne gudanar intravenously via musamman catheter. Yana kuma iya zama gudanar subcutaneously, a cikin abin da ake kira "kwala". Ya kamata a lura cewa a cikin farkon kwanaki biyu na lura da pancreatitis ya kamata a za'ayi da igiyar jini jiko. Shi ne kawai bayan da Pet za su iya daukar abinci ba tare da amai, magani iya gudanar a bushe ma ga 5-7 kwanaki.

Abin da ya zama sashi domin lura da miyagun ƙwayoyi "Gordoks"? Amfani a cikin karnuka talakawan size da kuma nauyi category (game da 15 kg) ya shafi gwamnati na mai magani a cikin wani adadin ba wucewa 10 dubu. KIU (sau uku a rana). Game da Cats (game da 5 kg), da sashi ya zama 5 dubu. KIU (a baya shawarar tuntubar wani likitan dabbobi).

Domin gwamnati na miyagun ƙwayoyi via IV abinda ke ciki na vial a wani sirinji, sa'an nan ja dabba fata kuma daidai kai da allura a cikin subcutaneous sarari. A wannan yanayin, da miyagun ƙwayoyi ne a sannu a hankali tura daga cikin sirinji.

magani Reviews

Bisa ga sake dubawa na likitoci da kuma dabbobi, da miyagun ƙwayoyi "Gordoks" quite yadda ya kamata da kuma sauri yi wa mai dagewa kuma m pancreatitis. Bugu da kari, yana da ikon dakatar da wani zub da jini.

The kawai drawback wannan magani abubuwa a matsayin babbar dama gefen effects, wanda zai iya har ma da kai ga mutuwa. Saboda haka, wannan magani ya kamata a yi amfani ne kawai a kan shaidarsu, kuma ba kawai don dalili na da halartar likita. Haka kuma, a lokacin da magani daga nufin wannan da mãsu haƙuri dole ne dole ne a karkashin tsauraran dubawa na likita.