Hemolytic anemia-Chauffard Minkowski: bincike da kuma magance

A anemia, da jini haemoglobin matakin saukad da sharply. Tare da wannan cuta cikin rãyukansu, su hadu da mai yawa mutane. Haka kuma, shi ba ya kauce gefe ko da kananan yara. Mai iri da cutar suna lalacewa ta hanyar matalauta rage cin abinci, rashin bitamin, ko shan wasu magunguna. Bayan kawar da duk cututtuka sa factor cropped. Daga cikin iri-iri na pathological tafiyar matakai kasaftawa daya wuya da matukar hatsari. Wannan hemolytic anemia-Chauffard Minkowski. Shi ke nan game da shi za a tattauna a yau labarin.

Mene ne anemia?

Karkashin anemia ne fiye gane a matsayin jihar na jiki, halin da kaifi dakushe Manuniya na ja da maikacin jini, da haemoglobin. Wasu irin cutar take kaiwa zuwa canji a cikin siffar ja jini Kwayoyin. Sun rasa su primary aiki a kan lokaci.

Anemia ne sau da yawa tare da wani iri-iri na cututtuka, amma ba primary. Wannan shi ne dalilin da ya sa ya kamata ka yi ba ba tare da barin hankali cuta. Wajibi ne kamar yadda wuri-wuri don gano dalilin da kuma kokarin kawar da.

Features hemolytic anemia

Kalmar "hemolytic anemia" ya hada da mai fadi da kungiyar cututtuka. Dukan su ne halin da na kowa pathogenesis. Karuwan halakar ja jini Kwayoyin haddasa karuwa a cikin bazuwar kayayyakin da kuma wani karuwa a erythropoiesis. Kalaman samuwar zai lalace ja jini Kwayoyin. Matakai na halaka su ne a hankali fara ĩkon tasarrufi a cikin sunadaran da fitowan da kuma maturation.

All haemolytic anemia yanaye kasu kashi biyu kungiyoyin: hereditary da samu. A cikin wannan labarin, za mu yi cikakken look at farko version. Don zama daidai, mun yi la'akari da cewa shi ne a hereditary anemia-Chauffard Minkowski.

A likita reference books za ka iya samun 'yan sunayen da yake bayani pathological tsari. Wannan microspherocytic anemia da hereditary spherocytosis, da kuma cuta-Chauffard Minkowski. Mafi sau da yawa amfani da sunan karshe da sunayen masana kimiyya, discoverers.

Cutar da ake dauke su sosai na kowa (1 a kowace 5 dubu. Population). An kamu yafi a mutane na arewacin Turai. A farko, ãyõyi bayyanannu a yara a wani wuri shekaru. Idan ba ka fara da su bi da cuta a cikin wani dace hanya domin ta mummunan tasiri a kan aiki na dukan kwayoyin.

A Sanadin kuma inji na cuta

Anemia Minkowski-Chauffard tare da tsangwama daga salula membranes na erythrocytes Tsarin da ayyuka. A sakamakon wadannan matakai, sun canja abin da siffar wani madauwari, zama gaggautsa. A farko alamun hemolysis - halakar ja jini Kwayoyin tare da lokaci daya saki na haemoglobin.

A wani m adam ja jini Kwayoyin a cikin siffar reminiscent na wani biconcave faifai, sabõda haka suka matsa musu kyauta ta hanyar tasoshin. A anemia, da membrane abubuwa na gina jiki kira da aka gaji da damuwa. Wannan take kaiwa zuwa shigar azzakari cikin farji na taya a cikin sel. Saboda wannan dalili, sun canja abin da siffar. Wucewa ta cikin jini, ja jini Kwayoyin suna da azaba mai tsanani maras kyau, kuma bayan wani lokaci za a fara rushe. Kan bango na gudana matakai, da matakin na ja da maikacin jini saukad da cika fuska, masu tasowa, hemolytic anemia.

Idan iyaye daya ya rigaya an kamu da wannan cuta, za dole wuce ta gādo ga yaro. Sosai da wuya rashin lafiya yara, ana haifuwarsu ne daidai da lafiya uwaye da kuma dads. A wannan yanayin, anemia tasowa kan bango na canje-canje a cikin DNA. A farko gene maye gurbi ya auku ko da a lokacin fetal ci gaba. Da ake bukata kafun ga ci gaban da cuta ne da tasiri a kan mahaifiyarka jiki da wadannan dalilai:

• radiation, X-haskoki.
• maye da nauyi karfe salts, hana fataucin miyagun kwayoyi, nicotine.
• virus hari.

Ƙarƙashin rinjayar da wadannan dalilai yiwu ba kawai anemia-Chauffard Minkowski, amma kuma mafi tsanani Pathology. Saboda haka, a lokacin daukar ciki, wata mace ya kamata kokarin kare jikinka.

A farko bayyanar cututtuka

The asibiti hoto da aka fi mayar da m da tsanani daga cikin pathological aiwatar da adadin modified erythrocytes. Da farko bayyanar cututtuka za a iya lura a yara na makarantan nasare da kuma farkon makaranta shekaru. A lokacin da irin wannan anemia yawanci undulating. Seizures hemolytic rikicin idan akwai babban adadin lokaci daya halakar ja da maikacin jini, bi da lokaci na shiru. A wannan yanayin, da cututtuka za su iya bambanta dan kadan.

Alal misali, interictal lokacin da cuta da aka bayyana ãyõyi na anemia. Daga cikin su akwai pallor na fata, mucous membranes ko idanu. Idan hemolytic rikicin na asibiti hoto da aka modified ya kuma bi da wadannan cututtuka:

1. Kara zafin jiki zuwa 38 digiri, ciwon kai, malaise.
2. A ci gaba da jaundice.
3. Pain a ciki, halin spastic hali.
4. Rashin jin daɗi a cikin hanta saboda ta karuwa.
5. Kumburi daga cikin baƙin ciki.

Hereditary hemolytic anemia-Chauffard Minkowski samu a manya. A mafi m dalilin neman magani a wannan yanayin ne yellowness da fata. Duk da haka, a mafi yawan lokuta, cutar ne asymptomatic. Marasa lafiya koyi da ta wanzu kwatsam kuma yawanci a lokacin wani zaman yau da kullum dubawa.

Medical jarrabawa

Ganewar asali na anemia-Chauffard Minkowski ne quite sauki. Idan ka zargin wata cuta, kuma ta bayyana da farko bayyanar cututtuka kamata kanemi shawara. Pathology na hematopoietic tsarin ne a cikin iyawa da wani hematologist. Bayan nazarin koken da haƙuri da iyalinsa tarihi gwani kamata duba fata da kuma sclera, gudanar da ciki palpation. Wajibi sanya ultrasonography na hanta da saifa, a matsayin alama da cuta ne da karuwa a cikin size daga wadannan jikuna.

Lokaci guda hematologist ba shugabanci zuwa yawan dakin gwaje-gwaje gwaje-gwaje. Hemolytic anemia-Chauffard Minkowski tabbatar da kasancewar wadannan canje-canje:

1. Fitsari: hemoglobinuria, ta ƙara gina jiki Manuniya da urobilin.
2. Biochemistry jini: rage cholesterol, lactate dehydrogenase, girma, da karuwa a tsaye ba bilirubin.
3. A binciken na ja jini Kwayoyin: reticulocytosis pronounced, raguwa a cell size, runtsẽwar osmotic kwanciyar hankali.
4. Janar bincike na jini: ESR hanzari, wani kadan karu a platelet da leukocyte rage launi nuna alama.

A karshe tabbatar da farko ƙarshe taimaka hali electrophoresis sunadarai na erythrocyte membrane a tare da su quantitation.

bambanci ganewar asali

Hemolytic anemia Minkowski-Chauffard yara wani lokacin sa matsaloli a lokacin da ganewar asali. Wannan cuta ne kama da sauran autoimmune pathologies bayyanar cututtuka. Saboda haka, likitoci ya kamata sane da wasu daga cikin fitattun da kuma halayyar ga irin wannan anemia bayyanar cututtuka.

Da farko muna magana ne game da wani kayyade predisposition. Kawai a cikin kwarai lokuta iyaye biyu ne gaba daya lafiya. A daya hannun, da rashin lafiya yaro za a iya gano wani jinsin canji a cikin kasusuwa na ragargaje. A m lokuta bugu da žari sanya Coombs samfurin. Idan bincike ne korau, da mãsu haƙuri yana goyan bayan anemia-Chauffard Minkowski. Ganewar asali ne daga yanzu kammala.

Conservative magani

Anemia far zaba saboda da tsananin. A lokacin lull, kamar yadda mai mulkin, baki ake bukata. A lokacin na gaba hari na haƙuri asibiti nan da nan.

Conservative lura da anemia-Chauffard Minkowski hada da wadannan matakan:

1. Sauyawa far erythrocyte taro, idan jini haemoglobin matakin saukad da matakin na 70 g / l.
2. Albumin aka nuna don lura da high rates na bilirubin.
3. Domin detoxification amfani da jiko far.
4. A cikin rashi na kar hemolytic rikicin misalta liyafar choleretic kwayoyi.

A tsawon lokaci da irin wannan far, da takamaiman kwayoyi da kuma su sashi - duk wadannan al'amurra ake yanke shawarar da likita a kan wani mutum akai.

gudanar da sa baki

Idan microspherocytic hemolytic anemia-Chauffard Minkowski zama mai tsanani, ra'ayin mazan jiya magani ba zai iya jimre da bayyana manufofin, da mãsu haƙuri an rika tiyata don cire baƙin ciki. Irin wannan dabarar ba zai iya gaba daya warkar da rashin lafiya. A daya hannun, bayan da baki na da yawan halaka ja jini Kwayoyin rage muhimmanci da kuma tsawo da rai sake zagayowar.

Hemolytic rikicin bayan da aiki ba maimaita, amma shi yana da yawan contraindications. Alal misali, kau na baƙin ciki ba da shawarar yara a karkashin 5 shekaru saboda da high mace-mace rates a cikin postoperative zamani. A downside na hanya aka dauke su rage jiki ta juriya game da kwayar kuma fungal cututtuka.

An madadin embodiment aka dauke su cire baƙin ciki endovascular occlusion. Wannan shi ne wani Hanyar magani don taimaka ne sau da yawa nemi a cikin ganewar asali "microspherocytic anemia-Chauffard Minkowski." A lokacin hanya, likita abun da ake sakawa cikin jikin wani magani da cewa tsokani spasms, da kuma baƙin ciki take kaiwa zuwa wani ciwon zuciya. Wasu daga shi sai kubutar da cikakken jinin samar da ba ya rasa ikon yãƙi cututtuka.

zai yiwu rikitarwa

Hemolytic anemia-Chauffard Minkowski makarantan nasare yara sau da yawa take kaiwa zuwa jinkiri a shafi tunanin mutum da kuma ta jiki ci gaba. Musamman idan iyaye na dogon lokaci bai nemi taimakon likita ko watsi da likita ta shawara.

A adult marasa lafiya, ya fi kowa wahala an dauki kan bango na gallstone cuta cuta da bilirubin metabolism. The abu ne cewa, hemolytic rikicin ne sau da yawa gani a matsayin farkon na ci gaba jaundice, don haka ya dace an jinkirta jiyya. A gaban duwatsu a cikin gallbladder bada shawarar cewa a cholecystectomy da splenectomy.

Kintacen dawo da

A kasa mai tsanani cuta da kuma dace hali na aiki cire baƙin ciki m hangen nesa. Gafarar yakan auku nan da nan bayan da hemolytic rikicin. Its duration iya bambanta, amma a mafi yawan lokuta shi ne game da shekara biyu.

hanyoyin hana

Anemia Minkowski-Chauffard ne hereditary. Saboda haka hana abin da ya faru da cuta ne ba zai yiwu. Domin ya hana m siffofin da cuta a cikin marasa lafiya bincikar lafiya tare da wani nau'i na anemia shi ne shawarar lokaci zuwa lokaci, sha da cikakken dubawa a hematologist.

A lokacin da shirin a ciki ya kamata a fahimci cewa da alama na bunkasa cutar a haifa ba yana da 50%. Saboda haka jariri ma ya nuna ci gaba da sa ido ta hanyar likita don gano pathologies a wani wuri mataki.