"Melofleks": umarnin don amfani. Abun da ke ciki, da sake dubawa, contraindications, analogs

A wasu yanayi, likitoci rubũta zuwa ga marasa lafiya magani "Melofleks"? Umurnai na amfani na ce kudi, anta, abun da ke ciki, analogs kuma saki siffofin za a gabatar a wannan labarin. Bugu da kari, daga shi za ka koyi ko ko ba wannan magani illa da kuma contraindications, da aka sani game da lokuta da yawan abin sama, magana da shi a matsayin haƙuri kuma sana'a, nawa koda halin kaka, da sauransu.

A abun da ke ciki na miyagun ƙwayoyi da kuma nau'i na ta saki

A abin da fom da aka kasuwanci miyagun ƙwayoyi "Melofleks"? Injections - shi ne ya kawai nau'i na release. A bayani ga intramuscular allura ƙunshi irin wannan wani kashi aiki a matsayin meloxicam. Bugu da kari, cikin halitta ya hada da ƙarin aka gyara. Wadannan sun hada da wadannan: meglumine, sodium chloride, glikofurfurol, glycine, poloxamer, sodium hydroxide bayani da kuma ruwa.

A kantin injections "Melofleks" wa'azi wanda za a gabatar nan, za a iya saya a kwali fakitoci na 5 ko 3 ampoules ciki (1.5 ml).

A pharmacological halaye na allura nufin

Mene ne magani "Melofleks" (Shots)? Umurnai na yin amfani da allura ya furta cewa, shi da dangantaka da anti-mai kumburi kwayoyi (ba steroidal). Wannan medicament ne enolovoy acid wanda aka samu, inda ya ke iya zuwa exert analgesic da antipyretic mataki.

Pronounced anti-mai kumburi sakamako na ce miyagun ƙwayoyi da aka shigar a kan duk model (misali) kumburi. Ka'idar aiki na wani medicament shi ne cewa shi ne iya inhibiting kira na prostaglandins, wanda aka, a gaskiya, an san shiga tsakani na kumburi.

Ya kamata a lura da cewa miyagun ƙwayoyi "Melofleks", farashin wanda ba sosai high, damuarn kira na prostaglandins a kumburi site yawa fiye da a cikin kodan ko da mucosa daga cikin ciki. Wadannan bambance-bambance da kai tsaye dangane da zabe hanawa na cyclooxygenase-2 kan cyclooxygenase-1. Masana sun ce cewa saboda da hanawa na Cox-2 samar da wani warkewa sakamako na shawara ba. Duk da haka, domin har abada inhibiting Cox-1 isoenzyme shi ne sau da yawa sosai sa illa a cikin kodan da kuma ciki.

A pharmacokinetics da miyagun ƙwayoyi

Bayan yin amfani da shiri "Melofleks 'ratings na wanda aka haxa, ta aiki bangaren da aka daure su jini sunadarai a cikin adadin 99%. Wannan medicament wuce ta jini-nama shãmaki, kuma ta shiga cikin synovial ruwa. A maida hankali a cikinta ne 50% na taro a jini.

A metabolism na medicament a cikin hanta (metabolized to m metabolites). Bayar da shirye-shiryen ta hanyar da hanji da kuma ta hanyar da kodan (a daidai sassa). Cikinsa da fitarwa yana nufin a unmodified fom in wani adadin na 5% na kullum kashi.

Alamomi ga yin amfani da NSAIDs

Idan wani sabawa aka nuna ta hanyar "Melofleks" (Shots)? Umurnai na amfani ƙunshi bayanin da ya wakilci magani da ake sa kawai a cikin wadannan lokuta:

• rheumatoid amosanin gabbai.
• a osteoarthritis.
• tare da ankylosing spondylitis (watau ankylosing spondylitis).

Ba za mu iya ce cewa irin wannan magani ne sau da yawa wajabta ga symptomatic magani, rage zafi da kumburi, waxanda suke da samuwa a lokacin da miyagun ƙwayoyi. Ya kamata kuma a ce cewa ci gaban da cutar da shi ba zai yi tasiri. Saboda haka, yana iya zama ba tare da wani tsoro ba don marasa lafiya da na sama diagnoses.

Contraindications ga yin amfani da NSAIDs

A wasu lokuta, injections kamata ba a yi amfani da "Melofleks"? Umarnin don amfani da mafita ƙunshi fairly manyan jerin contraindications. Saba da shi za ku iya zuwa yanzu.

• Karuwan haƙuri ji na ƙwarai to sauran anti-mai kumburi kwayoyi (ba steroidal).
• Hade polyposis maimaita paranasal sinuses da kuma hanci da Bronchial fuka, rashin ha} uri ga acetylsalicylic acid da kuma shirye-shirye pyrazolone jerin.
• Ulcerative raunuka membrane na ciki da kuma duodenum 12, musamman a cikin tsawon exacerbation.
• Hypersensitivity ga abubuwa na allura bayani.
• Active zub da jini daga cikin gastrointestinal fili.
• Yanayin haƙuri bayan kewaye tiyata (jijiyoyin zuciya jijiya).
• Yara da matasa (ba za a iya amfani da har zuwa shekaru 18).
• Koda gazawar (na kullum) a cikin marasa lafiya da suke yi ba, an hõre dialysis (CC kasa da 30 ml / min.).
• Kumburi hanji cuta.
• koda cuta (m).
• Hyperkalemia tabbatar.
• Hanta gazawar ko tsanani aiki cutar hanta.

Aikace-aikace na nufin m

A wasu lokuta da matsananci hankali wajabta magani "Melofleks"? Umurnai na yin amfani da allura bayani ya ƙunshi bayanin cewa ya kamata a sosai a hankali sanya tsofaffi da kuma a cikin marasa lafiya da jijiyoyin zuciya jijiya cuta, ciwon sukari, cerebrovascular cuta, zuciya rashin cin nasara (na kullum), dyslipidemia / hyperlipidemia, na gefe jijiya cuta, koda insufficiency ( tare da CC 30-60 ml / min), ulcerative raunuka na gastrointestinal fili a tarihi, gaban Helikobekter pylori kamuwa da cuta mai tsanani da kuma somatic cuta.

Har ila yau, tare da matsananci hankali da miyagun ƙwayoyi ya kamata a yi amfani da ga mutãne waɗanda suke shan taba da kuma shan wahala daga shan barasa. Bugu da kari, an haramta wa da wani dogon amfani da ce NSAIDs, kazalika da ta lokaci guda amfani da baka corticosteroids, ciki har da hanyar "Prednisolone", anticoagulants, ciki har da miyagun ƙwayoyi "Warfarin", antiplatelet, ciki har da magani "Clopidogrel", zabe reuptake hanawa serotonin, ciki har da magunguna "citalopram", "Fluoxetine", "Paroxetine" da "Sertraline".

Medicament "Melofleks": umarnin don amfani da

Kamar yadda aka nuna da miyagun ƙwayoyi da za a yi amfani da da kuma a cikin abin da allurai? Wajibi ne a shigar warai da kawai intramuscularly. Kamar wancan igiyar jini amfani ne tsananin haramta bayani.

Intramuscular gwamnati da miyagun ƙwayoyi aka nuna ne kawai domin na farko 'yan kwanaki na far. Daga bisani da haƙuri ne yawanci ba na baka NSAID.

Saboda haka a cikin abin da allurai yi amfani da miyagun ƙwayoyi domin a musamman cuta? Mun amsa wannan tambaya a halin yanzu.

• Anti-mai kumburi da kwayoyi don osteoarthritis exacerbation gudanar a wani adadin 7.5 MG da rana. Idan haƙuri da yanayin bai canja ba ga mafi alhẽri, wannan girma za a iya ƙara har zuwa 15 MG da rana.
• A ankylosing spondylitis da rheumatoid amosanin gabbai gabatar medicament aka gudanar a wani adadin na 15 MG da rana. Dangane da sakamako na bayani girma za a iya rage zuwa 7.5 MG da rana. An shawarar ba zuwa ƙetare kullum kashi na ce da nufin (15 MG).

Kamar yadda tsofaffi a gudanar da wani magani daga irin cututtuka kamar osteoarthritis (magani)? anti-kumburi kwayoyi ya kamata a yi amfani da tare da matsananci hankali. Tsawo magani daga ankylosing spondylitis da rheumatoid amosanin gabbai, da sashi ne 7.5 MG da rana. Waɗanda suke m zuwa gefen effects, magani ya kamata a fara da wannan sashi.

Marasa lafiya da suke kan dialysis, kuma suna da tsanani na koda insufficiency, miyagun ƙwayoyi haramta Raba-aiki mafi girma kullum kashi (7.5 MG da rana). A mutane da matsakaici ko matsananci koda dan kadan aiki (QC fiye da 25 ml / min.) Shin, ba za mu rage sashi.

illa

Me idan ya ce miyagun ƙwayoyi ba ya taimaka da haƙuri ko zuwa shafi ta barnatar? Table analogue kwayoyi ya zama ko da yaushe a hannun. Godiya ta, da mãsu haƙuri iya samun wani irin kayan aiki da shi ne mafi kyau ga jikinsa.

Shin injections anti-kumburi "Melofleks" illa? Bisa ga umarnin, da miyagun ƙwayoyi iya haifar da wani yawan mummunan sakamakon. Me? Ka yi la'akari da su a yanzu.

• Gawan jini: anemia, tromotsitopeniya, canje-canje a cikin jini kirga, ciki har da leukopenia.
• Tsarin narkewa kamar: dyspepsia, hyperbilirubinemia, tashin zuciya, ulcers gastroduodenal, amai, belching, zafi, ciki, esophagitis, maƙarƙashiya, zub da jini daga gastrointestinal fili, ciki har da boye, flatulence, stomatitis, zawo, mai shudewa ƙaruwa a hanta transaminases, hepatitis, perforation na narkewa kamar fili, gastritis da kuma colitis.
• Tsarin Numfashi: Bronchial fuka-hare a mutane rashin lafiyan NSAIDs da acetylsalicylic acid.
• Skin: rash, itching, photosensitivity, rash, bullous rash, Stevens-Johnson ciwo, erythema multiforme.
• CNS: tinnitus, vertigo, disorientation, ciwon kai, da ruɗewa, vertigo, wani tunanin lability , kuma somnolence.
• Urinary tsarin: m na koda gazawar, albuminuria, hypercreatininemia, hematuria, interstitial nephritis.
• Tasoshin da kuma zuciya palpitations, na gefe edema, kara na jini ga fuska, kuma Ya ƙãra jini.
• Alerji: anaphylactoid ko anaphylactic halayen, angioedema.
• Hankula: Heart hangen nesa, conjunctivitis, Heart hangen nesa.

lokuta da yawan abin sama

Abin da sakamakon bayyana daga waɗanda suka ƙẽtare kashi "Melofleks" miyagun ƙwayoyi (Shots)? Shedu ce cewa a irin haka sun tsananta kashi-da alaka da illa. Wannan ya ba Yunƙurin zuwa da wadannan cuta jihohi: epigastric zafi, m na koda gazawar, illa sani, na numfashi kama, tashin zuciya, zub da jini daga narkewa kamar fili da amai, asystole, kuma m hanta gazawar.

A hali na yawan abin sama symptomatic magani ake bukata. A wannan alkalization fitsari, diuresis da hemodialysis ba sosai m saboda da high dauri na miyagun ƙwayoyi da jini da sunadarai.

Specific shiriya a cikin aikace-aikace na kudi

Abin da dokoki da ya kamata a bi a cikin yin amfani da miyagun ƙwayoyi "Melofleks" (Shots)? Guest masana sun ce cikin bayani ya kamata a yi amfani da tare da matsananci hankali, musamman a lura da mutane da cututtuka na gastrointestinal fili a tarihi. Irin wannan marasa lafiya ya kamata a kula a kai a kai tare da likita. Idan kana da wani zub da jini, ko ulcers kamata nan da nan dakatar da yin amfani da kudi.

Kulawa ta musamman daga kwararru ya kamata a da nufin mutanen da suke bayar da rahoton cin gaban maras so illa daga mucous membranes da kuma fata. A irin wannan yanayi shi ne mafi alhẽri la'akari daina amfani da yin amfani da miyagun ƙwayoyi.

A marasa lafiya da rage zagawa da jini girma da kuma rage glomerular tacewa iya haifar da kullum na koda gazawar. Matsayin mai mulkin, wannan gefe sakamako ne gaba daya reversible. Amma da wannan manufa shi ne shawarar soke amfani da wani injectable bayani.

Lokacin gwaji kyautata, kazalika da naci transaminase dabi'u da kuma canza wasu sigogi na hanta miyagun ƙwayoyi aikace-aikace kamata kuma a tsaya. Haka kuma, tun da shi wajibi ne don nan da nan gudanar da wani iko gwaje-gwaje.

Don kwanan wata, babu bayani game da illar da miyagun ƙwayoyi a kan ikon fitar da motocin ko wasu sunadaran ba. Idan haƙuri yana CNS illa (gajiya, Heart hangen nesa, juwa ko jiri, kuma haka a.), Sa'an nan waɗannan ayyuka shi ne contraindicated.

Hulda da sauran kwayoyi

Shin da miyagun ƙwayoyi zuwa wasu kwayoyi "Melofleks", farashin wanda dabam a cikin kewayon 200-300 Rasha rubles?

Lokaci daya amfani da mahara NSAIDs kara hadarin erosive da ulcerative raunuka na gastrointestinal fili. Wannan shi ne dalilin da ya sa shi ba da shawarar a ce samfurin tare da sauran anti-mai kumburi kwayoyi.

A lokacin da yin amfani da miyagun ƙwayoyi da diuretic haƙuri ya kamata ka sha yalwa da ruwaye. Kamar haka na bukatar yau da kullum da kiwon lafiya da iko da koda aiki.

Masana sun ba da shawarar hada NSAIDs tare da kai tsaye ba anticoagulants, kamar yadda wannan na iya kara hadarin zub da jini saboda lalacewar da mucous membrane na hanji ko ciki, kazalika da danniya da platelet aiki. Wannan sakamako na iya haifar da lokaci daya amfani da ce shirye-shiryen da thrombolytic da antithrombotic jamiái.

Ya kamata kuma a lura da cewa medicament "Melofleks" iya kara maida hankali lithium a cikin jini zuwa mai guba matakan. Har ila yau, a lokacin da aka yi amfani da lokaci guda tare da samfurin "Methotrexate" ƙãra mummunan sakamako a kan jini.

colestyramine accelerates miyagun ƙwayoyi abu amfanin ƙasa, kara yarda da aiki abu na 50%. Ba za mu iya ce cewa NSAIDs rage tasiri na intrauterine maganin hana haifuwa na'urorin.

Allura "Melofleks": analogs

A halin yanzu, kantin magani, sarƙoƙi za a iya samu quite da dama analogues na ce miyagun ƙwayoyi. Ya kamata a lura da cewa farashin iya zama mafi girma a matsayin asali miyagun ƙwayoyi, da kuma a kasa.

Saboda haka, idan har bisa wani dalili kuna iya ba saya da wani bayani ga injections "Melofleks", to, dole ka zama mai amfani tebur analogues magunguna. Wannan zai ba ka damar sanya saya da ya dace magani, wanda a wata hanya ba, baya zuwa asali. Duk da haka, ya kamata a ce cewa irin wannan kwayoyi na iya samun wani mabanbanta illa, miyagun ƙwayoyi interactions da kuma contraindications. Shi ya sa kafin su yi amfani da shawarar tuntubar likita. Idan irin wannan damar ba ka aikata ba, ya kamata ka karanta a hankali da umarnin don amfani.

Saboda haka abin da analogues ya nuna da magani? Daga gare su, Ina so in yi musamman haskaka da wadannan kayayyakin: "Melofleks Rompharm", "Amelotex", "Bi-Xico", "Artrozan", "Lem", "liberum", "Matar", "Medsikam", "Melbek", "Meloxicam" "Mesipol", "Eksen-Sanovel", "Oksikamoks" da sauransu.

Shan magani a lokacin lactation, kuma a lokacin daukar ciki

Danniya na prostaglandin kira barnatar da shafi fetal ci gaba. Wannan shi ne dalilin da ya sa da miyagun ƙwayoyi kamata ba a yi amfani da lokacin daukar ciki. Idan dole, shi za a iya maye gurbinsu da wasu, mafi kafaffen wajen. Amma ga mace mai ciki ya kamata ko da yaushe tuntubar likita.

Ya kamata kuma a lura da cewa da miyagun ƙwayoyi da aka saki tare da nono madara, saboda haka ya zama dole a cikin tsawon aikace a daina nono-ciyar da wata baby.

Lokaci da kuma wuri na ajiya da miyagun ƙwayoyi

Injectable Magani "Melofleks" ya kamata a sanya a cikin wani duhu wuri, inda ba fallasa zuwa hasken rana kai tsaye. Haka kuma, shi ya zama samuwa ga kananan yara. Adana medicament desirably a zazzabi ba fiye da 25 digiri na 4 years. A karshen shiryayye rayuwa da amfani da miyagun ƙwayoyi ne tsananin haramta.