"Pipekuroniyu bromide": umarnin don amfani da

Magunguna shakatawa kwarangwal tsokoki, da ake amfani da yadu ba kawai a lokacin m hanyoyin da matsakaici da kuma dogon duration, amma kuma a da al'adar rauni, da nufin repositioning ko} afar roba gidajen abinci. "Pipekuroniyu bromide" yana nufin kungiyar antidepolyarizuyuschih relaxants kuma yana da wani matsakaicin tsawon lokaci na mataki na 50-70 minti dangane da halaye na da kwayoyin. Bari mu bincika umarnin don amfani da miyagun ƙwayoyi, da kuma musamman da amfani a m yi.

pharmacological faye hali

Ginshikai na mataki na miyagun ƙwayoyi hade da tarewa synaptic watsa a neuromuscular synapse. Saboda wannan, akwai hanawa daga cikin abin da ya faru na mataki m a cikin tsoka fiber membrane, kuma ta haka ne, da tsoka cell hasarar da ikon yi mu'ãmalar.

Tare da shafe tsawon daukan hotuna da miyagun ƙwayoyi yanaye "pipekuroniyu bromide" kwarangwal musculature hūta. Ganin cewa nicotinic cholinergic rabe na da irin located ba kawai a cikin contact yanki na efferent zaruruwa somatic juyayi tsarin da tsoka Kwayoyin na kwarangwal tsokoki da kuma ganglia a autonomic juyayi tsarin, da gabatarwar manyan allurai medicament sa ganglioblokiruyuschimi rauni sakamako. Wannan shi ne saboda da lõkacin fatara daga cikin watsa na jijiya turu zuwa postsynaptic membranes na neurons, wadda take kaiwa zuwa wani karu a duka biyu m da parasympathetic effects.

alamomi

Shiri "pipekuroniyu bromide" an nuna ga shakatawa na kwarangwal tsokoki a lokacin tiyata. Aiwatarwa na miyagun ƙwayoyi domin manufar tracheal intubation da inji iska.

contraindications

Kamar yadda miyagun ƙwayoyi zuwa "pipekuroniyu bromide" wa'azi, da miyagun ƙwayoyi ne cikakken contraindicated a gaban hypersensitivity kuma a gaban myasthenia (rare, genetically m cuta, wanda shi ne a take hakkin da zumudi a neuromuscular synapse ci gaba da kuma tsoka rauni).

Da miyagun ƙwayoyi ne contraindicated a marasa lafiya a farkon matakai na ciki. A baya matakai na miyagun ƙwayoyi za a iya amfani, kamar yadda crosses da placental shãmaki a qananan yawa.

illa

Da miyagun ƙwayoyi iya hana na ayyuka na tsakiya m tsarin, sa hypersensitivity mamaki.

Daga gefe na zuciya da jijiyoyin jini illa ya sa ta hanawa na cholinergic watsa a synapses. Yin haka na iya rage zuciya rate, m jini, ischemic tsokar rauni, kwakwalwa lalacewar dangantaka da rage perfusion.

Lokacin da fallasa su yiwu ciki na numfashi tsarin na numfashi aiki, da ya faru na apnea ko apnea (musamman a lokacin aftereffects da miyagun ƙwayoyi).

Da miyagun ƙwayoyi rinjayar da metabolism kuma zai iya haifar da wani karuwa a jini potassium matakin, kara matakin na ciki da ƙananan creatinine jini glucose matakan.

Drug "pipekuroniyu bromide" - umarnin don amfani da

Da miyagun ƙwayoyi ne gudanar kawai a karkashin kulawa da wani gwani. Kafin Drug Administration dole duba samuwar anticholinesterases ( "Neostegmina" ko "Pyridostigmine") ko anticholinergics ( "Atropine").

Bayan da magudi m haƙuri monitoring ne da za'ayi a lokacin dawo da lokaci bayan maganin sa barci da kuma haƙuri ga normalize tsoka sautin.

A sashi na medicament a kan tushen da hadaddun jarrabawa na haƙuri kuma gudanar da bincike data analysis awon dabaru. A gaban gazawar da na koda excretory aiki, aikin hanta gazawar, kiba - kashi ya zama m medicament.

The bayani ne shirya nan da nan kafin Drug Administration "pipekuroniyu bromide." Form miyagun ƙwayoyi saki - vials na lyophilized foda dauke 0.004 g na aiki abu.

Ga marasa lafiya da illa jini electrolyte auna da kuma acid-balance tushe ne ma ake bukata kashi gyara. Da fifiko akan rage ion taro a jini jini, hypothermia da kuma yin amfani da cardiac glycosides (a lokacin digitalization) ne iya tsawaita lokacin kiranka na miyagun ƙwayoyi. A cikin hali na tsoka shakatawa a cikin wannan rukuni na marasa lafiya da farko bukatar normalize electrolyte na jini, sa'an nan zuwa ga gudanar da wani tsoka shakatawa. A cikin hali na marasa lafiya da na kullum zuciya maye, jini wurare dabam dabam na iya rage tsawo da latent lokaci na miyagun ƙwayoyi sakamako (karuwa a lokaci tsakanin gwamnati da farko na sakamako).

Za ka iya amfani da miyagun ƙwayoyi a yara daga shekara 1. A wannan yanayin da shi dole ne a tuna da cewa yaro ta jiki ne kasa m da sakamakon da tsoka relaxant, kuma daidai da, a cimma da ake so sakamako, kashi na miyagun ƙwayoyi ya kamata a karu.

vacation miyagun ƙwayoyi

Rubũta da miyagun ƙwayoyi domin "pipekuroniyu bromide" girke-girke a Latin ba zai iya ko da halartar likita. Medical ma'aikata na'am da m abubuwa daga jerin A kawai a kan bukatar da kuma a kan tushen da jihar. A wani raba harka, "pipekuroniyu bromide" girke-girke na iya rubũta gwani ta amfani da "ja" nau'i, duk da haka, ba duk asibiti cibiyar sadarwa suna da hakkin su ganin kwayoyi da kuma miyagun kwayoyi, ciki har da tsoka relaxants.

cinikayya sunayen

A pharmaceutical kasuwar miyagun ƙwayoyi samuwa a karkashin irin wannan cinikayya sunayen matsayin "Arduan" "Vero pipekuroniyu", "Aperamid", "pipekuroniyu bromide." Ciniki sunan da miyagun ƙwayoyi ne dogara a kan manufacturer, samar da wani magani da pharmaceutical kasuwar.

yawan abin sama

An yawan abin sama da miyagun ƙwayoyi da kuma rage sakamako ne zai yiwu saboda da gabatarwar anticholinesterases. Wadannan kwayoyi taimaka wajen kara maida hankali na neurotransmitter acetylcholine, game da shi, gasar tare da tsoka relaxant ga dauri shafukan kan tsoka mai amsa sigina.

Har ila yau, warkewa a cikin matakan da yawan abin sama tsara ƙara jini, kula da m jikin ayyuka, ciki har da a kudi na inji iska.

Drug interactions

Da miyagun ƙwayoyi ba za a iya gauraye da daban-daban jiko mafita, fãce isotonic mafita daga sodium chloride, kuma dextrose. A ci gaba da miyagun ƙwayoyi sakamako slows saukar, da tasiri warkewa kashi ne ya karu a karkashin yanayin preoperative gwamnati zuwa haƙuri da cholinesterase hanawa.

A wani hadin gwiwa aikace-aikace tare da tsoka relaxant narcotic analgesics yiwu ciki na numfashi cibiyar da ci gaban barci apnea.

Amfani da miyagun ƙwayoyi da depolarizing tsoka relaxants irin mataki zai iya duka biyu inganta da kuma rage overall tsoka relaxant sakamako. Wannan shã'aninku ne saboda da sashi na kwayoyi, lokaci na gwamnati, kuma mutum ji na ƙwarai to miyagun ƙwayoyi.

ƙarshe

Dauke da tsoka shakatawa a lokacin tiyata - wani muhimmin ɓangare na wani Hadakar maganin sa barci. Drug "pipekuroniyu bromide" an samu nasarar yi amfani da likita yi domin wadannan dalilai.

Yana dole ne a tuna da cewa gabatarwar da miyagun ƙwayoyi ba kawai yana sa shakatawa na kwarangwal tsokoki alhakin son rai motsi, amma kuma Yanã inna na numfashi tsokoki. Ganin wannan, da miyagun ƙwayoyi da ake amfani da kawai a karkashin yanayi da kuma m m kula raka'a.