"Quinidine": umarnin don amfani, abun da ke ciki, description da kuma sake dubawa

Me ya sa muke bukatar wani kayan aiki irin su "quinidine"? Umarnin don amfani, price, da kuma sake dubawa da nada da miyagun ƙwayoyi aka gabatar a kasa. Za ka kuma koyi abin da pharmacological Properties halayyar da miyagun ƙwayoyi, ko yana cikin mataki gefen hali da ko yana da wani hani don amfani.

A abun da ke ciki, siffar, description

A abin da fom pharmaceutical kamfanonin yin magani "quinidine"? Umurnai na Amfani, a haɗe zuwa wannan wajen, shi ne cewa shi za a iya saya a cikin nau'i na lebur da zagaye Allunan. Bã su da wani shafe tsawon sakamako da kuma film-mai rufi.

Babban sashi na wannan magani ne quinidine sulfate. Umurnai, samfurin bayanin ba ya bayar da wani bayani a kan ƙarin abubuwa.

Pharmaceuticals Pharmaceutical Products

Mene ne kwayoyi "quinidine"? Umarnin don amfani, description, reviews sun ruwaito cewa yana da wani magani domin Class IA arrhythmia. Shi ne iya rage da kai daga ions ta hanyar Na tashoshi azumi cell ganuwar cardiomyocytes kuma rage gudu iyaka depolarization da kuma ƙara da duration na aikin m da kuma tsaurin (tasiri) tsawon lokaci.

Yanayin aiki na wani medicament attenuates tsokar excitability, slows automaticity da AV-madugu a nodes, cuta reshe block, atrial da kuma da sauran fannin jiki. Kuma dauke nufin yana da vagolytic sakamako bayyana m-anticholinergic sakamako, rage aiki (contractility) na zuciya tsoka, kuma Yanã da wani raguwa a jini.

Properties na da miyagun ƙwayoyi

Mene ne na ƙwarai ne magani kamar yadda "quinidine"? Umurnai na amfani Notes cewa shi zai iya samun mummunan inotropic sakamako. Wannan na faruwa a sakamakon deceleration na ciki makamashi hira tsari a mitochondria. Game da antiarrhythmic kaddarorin da miyagun ƙwayoyi, suna hade da gaban amide kungiyoyin a cikin kwayoyin tsarin da aiki abu.

A cewar masana, da ci wannan medicament an rage muhimmanci zumudi da yaduwa gudu, wanda ake dangantawa da daukan hotuna na aiki miyagun ƙwayoyi bangaren da aiwatar da depolarization.

Suppressing m-cholinergic rabe, dauke da miyagun ƙwayoyi stimulates AV-madugu. A warkewa allurai shi farfado hypotensive Properties hade tare da ragewa sautin gefe jijiyoyinmu kuma jijiyoyi, kazalika da wani mummunan inotropic sakamako.

Ba za mu iya ce cewa wannan magani ne iya nuna gida irritating sakamako. Shi ma yana da analgesic da antipyretic Properties wanda ake dangantawa da wani depressing sakamako a kan kwakwalwa.

A pharmacokinetic halaye na

Tunawa ko irin wannan aiki sashi daga cikin miyagun ƙwayoyi a matsayin quinidine sulfate? Umurnai na amfani sanar da cewa liyafar da wani baka wakili inganta ta mafi girma maida hankali a cikin jini bayan 95 minti.

Reaction wannan tare da sunadarai medicament ne game da 77-80%. Its biotransformation auku a cikin hanta. Duk da haka, wasu Kalam sun kafa cardiotonic mataki.

A rabin rayuwa na wannan kayan aiki ne kamar 7 hours. Yana da aka kwashe a cikin kodan. By acidification fitsari tukar tumbi medicament ƙaruwa da kuma lokacin da ta alkalization - hana.

Daga abin da aka wajabta?

Mene ne alamomi na yin amfani da miyagun ƙwayoyi yana da "quinidine"? Umurnai na Amfani furta cewa, manufar da miyagun ƙwayoyi ne wajaba kawai a cikin wadannan lokuta:

• a atrial tachycardia, AV-tachycardias, extrasystoles na ramin zuciya da kuma supraventricular, hare-haren na atrial fibrillation da flutter.
• su hana kai hare-hare na tachycardia (supraventricular da kuma na ramin zuciya), da kuma na ramin zuciya fibrillation.
• bayan da cardioversion don kula da sinus kari.

Haramta yin amfani

Mene ne yanayin haƙuri hana amfani da magani "quinidine"? Umurnai na amfani (da farashin da magunguna da aka jera a kasa) rahotanni na contraindications da miyagun ƙwayoyi, kamar:

• cardiogenic buga.
• AV-block (na biyu ko na uku digiri).
• thrombocytopenic purpura, wanda ɓullo da bayan shan miyagun ƙwayoyi.
• cuta (tsanani) intraventricular madugu.
• dam reshe block.
• Digitalis maye, wanda yana tare da madugu munanan;
• wani rashin lafiyan dauki ga miyagun ƙwayoyi.
• myasthenia gravis.

Medicament "quinidine": umarnin don amfani da

Yarda da kayan aiki ya zama cikin 60 minutes kafin ko bayan 125 minti bayan ci abinci tare da cikakken gilashin ruwa. Idan kana so ka rage irritant sakamakon da miyagun ƙwayoyi a kan mucous membrane na narkewa kamar fili, shi wajibi ne don maye gurbin da ruwa tare da madara.

Tsawo miyagun ƙwayoyi ba da shawarar tauna ko murkushe.

A misali sashi yana dauke 200-300 MG Allunan sau hudu a rana. Idan supraventricular tachycardia (tare da paroxysms) wannan adadin da aka karu zuwa 400-600 MG kowane 3 hours kafin cikakken taimako na paroxysm. A atrial fibrillation, medicament samun 200 MG kowane 2 chasa (5-8 sau yau da kullum). Cikinsa da tabbatarwa kashi ne 200-300 MG sau hudu a rana.

Alternative regimens: 400 MG (idan harin da aka ba docked, 200 MG) kowace 60 minutes har sai da cikakken ƙarshe na hari, ko a cimma a total sashi na 1 g

A babu illa bayan na farko da kashi a cikin m liyafar da adadin medicament da za a karu zuwa 600 MG. Shan da miyagun ƙwayoyi a wuce haddi na 4 grams da rana da aka haramta.

Dosing yara

A wani kashi na magani wajabta wa yara "quinidine Dyuruls"? Umarnin don amfani, pediatricians ratings bayyana cewa wani misali sashi na wannan wakili ga jariran ne 6 MG / kg 5 sau per day. Prescribers ya zama kawai wani gogaggen likita, tsananin a kan shaida.

Ayyuka da-hali

Abin da mummunan sakamakon na iya faruwa bayan yin amfani da miyagun ƙwayoyi "quinidine Durules"? Umarnin don amfani, bayanin wannan miyagun ƙwayoyi da shawara da wadannan m halayen:

• asthenia, fadada QRS tazara, myasthenia gravis.
• ectopic na ramin zuciya beats, ji hasara.
• asarar ci, na ramin zuciya fibrillation, jijiya thrombosis, m jini;
• na gani disturbances, na ramin zuciya tachycardia, paroxysmal, tinnitus,
• asystole.
• tashin zuciya, sinus bradycardia, hepatitis, ciwon mara, da ruɗewa.
• gastralgia, ciwon kai, amai, thrombocytopenia, zawo, juwa ko jiri, hemolytic anemia.
• zazzabi, lupus-kamar ciwo, fata na gaggawa.

lokuta da yawan abin sama

Mene ne bayyanar cututtuka na yawan abin sama na iya haifar da magani "quinidine Dyuruls"? Umurnai, comments daga masana magana game da irin wannan manifestations kamar yadda tinnitus, ciki na cardiac aiki, drop a jini, juwa ko jiri, atrial flutter, diplopia, quinidine buga, ji hasãra.

Don kawar da irin wannan jihohin shafi wajabta ciki lavage, oxygen wadata, da hawan jinni da jamiái, pacing, hemodialysis da ventilator.

miyagun ƙwayoyi interactions

Yadda za mu bi da miyagun ƙwayoyi interacts da abu kamar yadda quinine? Umurnai na amfani (da farashin sake dubawa na medicament za a gabatar a karshen cikin labarin) ya ruwaito cewa wannan hade qara yawan guba na biyu.

Har ila yau, "quinidine" kwayoyi hulɗa tare da wadannan magunguna:

• Antiarrhythmic kwayoyi inganta cardiodepressive mataki.
• Anticholinesterase kwayoyi da kuma magunguna bunkasa effects kalisodergaszczye "Quinidine".
• Anticonvulsant kwayoyi rage jini matakan "Quinidine" da kuma rage ingancinta saboda ruri na ta metabolism.
• Laxatives rage tasiri da kuma maida hankali da miyagun ƙwayoyi a jini a karkashin review.
• Magunguna alkalising da fitsari, na kara hadarin mai guba halayen.
• Kwayoyi "amiloride" da "Amiodarone" rage tasiri na "Quinidine" da kuma tsawaita ta tazara QT, bi da bi.
• Acetylsalicylic acid kara zub da jini, petechiae da kuma inganta harkokin zub da jini daga narkewa kamar gabobin.
• Medicaments "Warfarin" da "Verapamil" - inganta anticoagulant sakamako na farko da na biyu rage kudi na tukar tumbi.
• Drug "Haloperidol" - qara da abun ciki a cikin jini da kuma kara hadarin m halayen.
• Kwayoyi "Hydroxyzine" da "dextromethorphan" - qara da alama na tsanani arrhythmia a liyafar na farko da na biyu a cikin jini.

takamaiman bayanai

Tare da musamman hankali ya bayyana magani bada shawarar ga na kullum zuciya maye mataki 2-3, tachyarrhythmia (na ramin zuciya) tare da wani elongation tazara QT, sinus kumburi, AV-kawancen 1st digiri, asma, hyperthyroidism, hypotension, m cutar, emphysema , kwana-ƙulli glaucoma, hypokalemia, hanta gazawar, thrombocytopenia, prostate hyperplasia, na kullum na koda gazawar, lactation, daukar ciki da psoriasis.

Mutane da myocarditis da sauran tsokar cututtuka lokacin samun "Quinidine" Regular likita iko ake bukata. Kafin jiyya, da mãsu haƙuri dole ne yin gyara na bayyanar cututtuka na hypokalemia da kuma gazawar da zuciya.

A far ake bukata don kullum saka idanu da ECG data na gefe jini da kuma hemodynamics.

Similar wajen, farashin

Drug analogues sun dauke da wani yawa. Masana sun sanyã wa su da wadannan nufin: "Kinidin Durules", "Bretilat", "procainamide", "Etatsizin" "Lidocaine", "Amiokordin", "Propanorm", "Amiodarone" "Verapamil", "Propranolol", "Ritmonorm ".

Amma ga farashin irin magunguna a matsayin "quinidine" da "quinidine Durules", da mazaunan ƙasarmu, su ne ba a sani ba saboda gaskiyar cewa wadannan kwayoyi an daina sayar a Rasha. Duk da haka, da suka za a iya saya a Ukraine. The kudin da kwayoyi a cikin kasar ne game da 540 da kuma 670-679 hryvnia, bi da bi, wanda shi ne daidai da 1380 da kuma 1760-1780 rubles.

reviews

Abin da mutane suka ce game da dauke medicament likitoci da sauran kwararru? A cewar su, da wannan kayan aiki tabbatar da matukar tasiri antiarrhythmic miyagun ƙwayoyi, wanda shi ne mai kyau kuma da sauri isa ya yi wa cututtuka irin na ramin zuciya da kuma supraventricular tachycardia. Duk da haka, ya kamata a lura da cewa search for "quinidine" kwaya a Rasha Pharmacy ne ba zai yiwu. Wannan shi ne saboda a gaskiya wannan magani aka cire daga free zagayawa da aka daina amfani da su a asibitoci. Doctors bayyana wannan halin da ake ciki da cewa akwai mafi aminci kuma mafi inganci, kazalika da araha takwarorinsu a cikin Pharmaceutical kasuwar, wanda ake rayayye amfani ga wannan alamomi. A wannan yanayin, masana sun ce quinidine sulfate ya ci gaba da za a yi amfani da matsayin bijiro da batun kafa na multicomponent abubuwa da yawa a cikin anti-arrhythmic kwayoyi.