"Amoxiclav 625": umarnin don amfani, real takwarorinsu

Daga cikin antimicrobial jamiái a cikin shirye-shiryen "Amoxiclav 625" haƙuri shedu da kuma kwararru mafi bayyananniyar. Da miyagun ƙwayoyi aka dauke su mafi tartsatsi kwayoyin da haka cancanci fadi fitarwa. Saboda da fadi da kewayon ayyuka, da aminci daga yara da kuma lactating mata, "Amoxicillin-clavulanate" kusan gama maida hankali ne akan wani fanni na empirical far outpatient numfashi da kuma urinary cututtuka.

Saki Jerin ayyukan da analogues

Shiri "Amoksiklav 625" samar da Basulabe Lek da positioned a matsayin miyagun ƙwayoyi aiki abu ne aminopenicillin amoxicillin da clavulanic acid. A farko taka rawar da kwayoyin da ke acid kare da kwayan beta-lactamases. Kamar yadda wani ɓangare na "Amoksiklav 625 MG" miyagun ƙwayoyi Allunan dauki kashi 500 MG na kwayoyin, da kuma 125 MG na clavulanate sababbin shiga.

A shirye-shiryen da aiki abu amoxycillin samar a karkashin wani iri-iri sunayen. A mafi ingantaccen analogues suna da wadannan kare aminopenicillin "Amoklav", "Augmentin", "Flemoklav", "Amklav", "Farmentin", "Amoksikar Plus", "ƙara", "Medoklav". Akwai kuma unprotected penicillins, wanda suke analogues na aji "Amoksiklava": "Amoxicillin", "Amoksikar", "Amosin", "Hikontsil" da sauransu. Su dace da aka dauke su a game da wannan.

A munasaba da miyagun ƙwayoyi

A cikin shirye-shiryen "Amoxiclav 625" comments daga masana ne mai haske. Wannan ingantaccen medicament, daya daga cikin kawai baka antimicrobial kwayoyi da halin low illa. Domin wannan dalili aka yi amfani da dukan lokuta a wadda amoxicillin ya dace. Kuma "Amoxiclav" shi ne wakilin hada kwayoyi. An kare clavulanic acid da penicillinase, wani enzyme cewa halakar da lactam zobe na kwayoyin. Godiya ga kariya na "Amoxiclav" ya zama mafi aiki tare da girmamawa ga da ake dasu Kwayoyin.

shaidar

A haɗe zuwa da miyagun ƙwayoyi "Amoxiclav 625" manual ƙunshi jagororin ga cututtuka, da magani daga wanda aka yarda a yi amfani da wani kwayoyin. Wannan sau da yawa tasowa numfashi, gastrointestinal, genitourinary cututtuka na m ko matsakaici mai tsanani. A milder siffofin dace monotherapy, alhãli kuwa matsakaici da kuma mai tsanani dole ne a bi a cikin inpatient unguwanni na kwayoyin hade. A general, alamomi ga yin amfani da "Amoxiclav 625 MG na" shiri jagora ya bayyana kamar haka:

• cututtuka daga cikin manya na numfashi gabobin (na kullum da kuma m siffofin tonsillitis, pharyngitis, sinusitis, otitis kafofin watsa labarai).
• cututtuka na ƙananan numfashi fili cututtuka (m kuma na kullum siffofin mashako, ciwon huhu).
• kwayan cututtuka na urogenital tsarin (pyelonephritis, urethritis, cystitis, oophoritis, pelvic kumburi, endometritis, kabba da ciwon sanyi, chancroid).
• kullum osteomyelitis.
• fata cututtuka, kamu dabba cizon, rauni mulkin mallaka da kwayoyin.
• periodontitis.

Domin da haƙuri, da farko tushen bayanai game da "Amoxiclav" shirye-shiryen - umurci manual. 625 MG na da miyagun ƙwayoyi abu, kaddamarda triplicate ga ya fara tasawa, za a iya yadda ya kamata mu bi cututtuka na numfashi tsarin sa ta gram-tabbatacce advantageously Flora. Kuma a Ari magani lokaci ne yawanci 5-7 kwana.

contraindications

Da miyagun ƙwayoyi ta aminci rikodi da kuma low yawan guba aji na penicillin ba ware gaban contraindications.

Bã su da wani kadan magani. Suna da alaka da ko dai zuwa gaban concomitant cututtuka, rashin lafiyan dauki ko physiological jihar da kwayoyin. Contraindications sun hada da:

• kasancewa nuni da abin da ya faru na cholestatic jaundice, ta ƙara aminotransferase aiki ko ci gaban da hepatitis sa ta a baya aikace-aikace "Amoksiklava", ta analogs ko wakilan kungiyar na penicillins.
• hanta insufficiency, lymphatic cutar sankarar bargo, mononucleosis saboda worsening da lambar kuma mai tsanani daga illa.
• rashin lafiyan wayar da miyagun ƙwayoyi, ko da aka gyara.
• alamomi na zargin nan da nan irin rashin lafiyan halayen lokacin shan wasu beta-lactam antimicrobial jamiái.
• zumunta lokaci contraindications: ciki a cikin 3rd trimester na lactation.

A hadarin tasowa allergies

Idan haƙuri ta tarihi akwai wani tunani da na gida irin alerji, "Amoxiclav" ba su rababbe. Idan ɓullo da anaphylaxis ko angioedema a mayar da martani ga karbar wasu beta-lactam antimicrobial jamiái, da "Amoxicillin-clavulanate" ya kamata kuma ba a karɓa. Sa'an nan da miyagun ƙwayoyi na zabi ne wakilin wani yawan macrolides a matsakaiciya Hakika, ko da wani fluoroquinolone.

dosing regimens

The adadin miyagun ƙwayoyi "Amoksiklav 625 MG," abin da ake bukata domin lura da dogara a kan shekaru da kuma nauyi na haƙuri. Numfashi cututtuka tunanin mutuntaka sanya har zuwa 2 grams domin manya da 1.3 grams na matasa. The "Amoxiclav" a wani kashi na 625 MG ne kawai matashi da adult miyagun ƙwayoyi. Ga yara a karkashin shekaru 12 da haihuwa, akwai kwayoyi a ƙananan allurai.

Standard sashi don wani mutum yin la'akari 40 kg kuma a kan shekaru 12 da haihuwa shi ne 625 MG sau biyu a rana. Manya shekaru 18 da shekaru wajabta 625 MG sau uku a rana. Wannan shi ya isa ga jiyya na matsakaici da kuma haske, da cewa shi ne, outpatient cututtuka na fata, numfashi, urogenital tsarin. A tsanani cututtuka sanya 1000 MG (875 MG na amoxycillin da clavulanate 125) sau biyu a rana. Yarda duffai uku aikace-aikace na 1000 MG.

gefen sakamako

Duk da isasshen fadin warkewa mataki, akwai da dama daga illa. Su suna hade da na gida cuta na hanji da kuma na ciki da ayyuka, kazalika saboda maye lalata kayayyakin na kwayan Kwayoyin, kamar yadda kwayoyin bactericidal sakamako.

A mafi m (1-10%) ne lokuta da tashin zuciya, amai ko zawo faruwa bayan da aikace-aikace na antimicrobial wakili. Kuma suka bayyana 2-4 kwanaki bayan m. Muhimmanci ƙara yiwuwar dyspepsia riga data kasance hargitsi a cikin hanji halaye, da kuma wasu rakiyar cututtuka: pancreatitis da excretory insufficiency, enteritis yanayin bayan resection na ciki ko hanji, na kullum colitis.

A rukuni na wanda ba safai ba ne rikitarwa (0,001-0,0001%) ne hanta cuta: ƙãra transaminases da kuma alamomi na hepatocyte cytolysis, cholestasis kuma jaundice, leukopenia. A mita angioedema, urticaria da anaphylaxis ne unspecified. Dalilin wannan shi ne a hankali a hankali karuwa a yawan rashin lafiyan halayen saboda farkon wayar da yara.

Daga baya, za dole kai ga wani raguwa a muhimmancin warkewa miyagun ƙwayoyi "Amoxiclav". Umurnai na amfani 625-MG kwamfutar hannu ba tukuna haramta yin amfani da masu jego. Duk da haka, wannan na iya zarar faruwa. Sa'an nan kuma ka bukatar ka nemi wani sabon maganin da amino da irin wannan dace. Babu shakka, cewa sabon sinadaran abu da aka hada da gwada, amma da aiwatar har tattalin arziki disadvantageous, saboda "Amoxiclav" ya gana da bukatun na clinicians.

Yanayin aiki a lokacin daukar ciki da kuma lactation

Bisa ga FDA bayanai, "Amoxiclav" ba shi da wani teratogenic sakamako. Wannan ƙarshe da aka kai bayan gudanar da bincike a kan dabbobi, domin duk analogues da miyagun ƙwayoyi kunshe a Category B da FDA (USA). Duk da haka, saboda m fargabar worsening toxicosis "Amoxiclav 625" a lokacin daukar ciki kusan ba sanya a farko trimester. A II kuma III awo na ta liyafar da aka halatta.

Aminopenicillin a alamarsu nawa a cikin ƙirjinka madara, wanda fada a cikin gastrointestinal fili da jariri. Duk da haka, muhimman keta cikin jikinsa, shi ba ya haifar da, saboda abin da "Amoxiclav 625" ba zai iya soke a lokacin lactation. The kawai ware lokuta na rashin lafiyan halayen da yaro ko vulvovaginal mucous membranes ko narkewa kamar fili, sakamakon da aikace-aikace na "Amoxicillin". Sa'an nan kuma ya na bukatar ko dai da yarjejeniyoyin da uwar samun wani antimicrobial wakili, ko - a mucosal candidiasis - ba don shãyar da mãma.

miyagun ƙwayoyi aminci fasalin

Allunan "Amoxiclav 625" ne mai basira m bakan da warkewa mataki, ta haka ne guje guba. Har ila yau, yana da wani tsakiyar effects, saboda abin da za a iya bai wa marasa lafiya da suke gudãnar da abin hawa ko wasu motsi sunadaran. Ya ba ya haifar da take hakki na memory, sani, da hankali, ko tunani.

Duk da haka, akwai wani yawan abin sama ciwo miyagun ƙwayoyi. Irin haka ne m, kuma yana faruwa ne musamman a lokuta tsoma bakin guda kashi na 5 ko fiye grams da miyagun ƙwayoyi. A bayyanar cututtuka ne da wadannan halaye: diarrheal cuta hade da tsananin ciwon mara, bloating, zawo, tashin zuciya da kuma wani lokacin amai.

Akwai lokuta crystalluria, dabbar ta hanyar canjin da ci daga amoxicillin, wani lokacin kai ga ci gaban da na koda gazawar. Duk da haka, wannan sabon abu zai iya faruwa lokacin da samun wani warkewa sashi daga cikin miyagun ƙwayoyi. Yana nufin wani nefroprotektsiya magani da kuma dialysis, damar cire daga jinin amoxicillin da clavulanic acid.

rigakafi

Marasa lafiya da lymphatic cutar sankarar bargo, ko kuma dauke da kwayar cutar mononucleosis miyagun ƙwayoyi "Amoksiklav 625", analogs da generics ba a nuna saboda da high alama na morbilliform kurji. Kuma saboda karu a da tasiri na baka hana a lokacin jiyya "Amoxicillin" ake bukata don gaba da kariya a kan maras so ciki shãmaki hanyoyin (kwaroron roba).

Tare da ci gaban zawo a lokacin amfani da "Amoksiklava" na bukatar kau da kwayoyin da ke lura da colitis (pseudomembranous ko hemorrhagic). A wannan halin da ake ciki, da aikace-aikace ne inadmissible "Loperamide". Har ila yau, tsawon lokaci aikace-aikace "Amoksiklava" na taimaka wa ci gaban da yawa da ake dasu mazauna rigakafi ga antimicrobials. Sun iya sa rikitarwa da wannan cuta.

Known miyagun ƙwayoyi interactions

Urikozostatichesky miyagun ƙwayoyi "allopurinol" a liyafar tare da "Amoksiklava" na kara hadarin fata rashes. Aikace-aikace urikozuricheskogo nufin "Probenecid", "oxyphenbutazone," "phenylbutazone", "sulfinpyrazone" ko acetylsalicylic acid rage kasafi na aminopenicillin (amma ba clavulanic acid), saboda wanda dan kadan qara taro na kwayoyin a cikin jini magani kuma tsawanta ta effects.

Hade miyagun ƙwayoyi "Amoksiklav 625 MG" tare da bacteriostatic antimicrobials m saboda juna danniya yadda ya dace. Sauran shirye-shirye dauke da amoxicillin, kuma ya kamata a hade tare da bacteriostatic: chloramphenicol, macrolides, tetracyclines da kuma sulfonamides. Hade da bactericidal maganin rigakafi take kaiwa zuwa juna karuwa antimicrobial aiki.

Aiwatar "Amoxiclav" a lokacin far, baka hana kuka da kansa saboda hadarin ya karu prothrombin lokaci da kuma thrombosis. A wannan maganin hana haifuwa tasiri ne rage muhimmanci. Sauran m bakan maganin rigakafi ma lũra da sakamako na rage tasiri na baka maganin hana haifuwa shirye-shirye.

Da amfani da "Amoksiklava" oportunisticheskih mu bi da cututtuka tasowa a kan wani bango na methotrexate far, muhimmanci ƙara da yawan guba na karshen. Wannan qara Yiwuwar thrombocytopenia, leukopenia, fata ulcers, gastrointestinal ulcers da erosions. Sa'an nan kuma ya bada shawarar a daina aminopenicillin amfani macrolides, ci gaba da kara lura da methotrexate.

Kamar yadda da wani m-bakan kwayoyin, "Amoxiclav" qara yadda ya dace na kai tsaye ba anticoagulants. Far "warfarin" saboda zalunci na antimicrobial jamiái daga kwayoyin da haduwa bitamin K take kaiwa zuwa wani karu a prothrombin index kuma Ya ƙãra INR. A sakamakon haka ne mafi girma hadarin da zub da jini.

Al'amurran da hada antimicrobial far

Drug "Amoxiclav 625" kuma ta Generic takwarorinsu suna da ikon ƙara da alama na zawo, idan amfani da sauran antimicrobial jamiái. Duk wani azuzuwan na maganin rigakafi tare da amoxicillin muhimmanci mafi kusantar su sa zawo, wanda ba za a iya bi da tare da taimakon azzaluman hanginsu. Irin wannan shiri ne "loperamide" da kuma ta analogues, contraindicated a dauke da kwayar cutar gudawa. A wannan yanayin, zawo ya sa ta hanyar yin amfani da "Amoksiklava" ya kamata a bi da maganin rigakafi.