Da miyagun ƙwayoyi "Aspekard": umarnin don amfani, analogs, reviews

Acetylsalicylic acid (ASA) tana nufin kwayoyi tare da antipyretic, anti-kumburi da antiplatelet effects. A likita yi da shi da ake amfani da fiye da 125 da shekaru, saboda shi ne daya daga cikin mafi karatu kwayoyi. Cikinsa ASA yanzu da akwai matsayin kardioformy zuwa rage hadarin jijiyoyin zuciya jijiya thrombosis, wanda ya hana ci gaban tsokar zuciya infarction. A misali ne da shirye-shiryen "Aspekard" wanda ya ƙunshi acetylsalicylic acid a cikin wani kashi mafi kyau duka domin antiplatelet sakamako.

Bayani a kan saki tsari da kuma Manufacturer

A manufacturer da miyagun ƙwayoyi ne Ukrainian kamfanin "Stirolbiopharm". Haka kuma, da masana'antu da fasaha amfani, samar a cikin form zheludochnorastvorimoy siffofin a kashi na 100 MG da kwamfutar hannu. Hanyar Allunan layout:

• kartani 120 Allunan (10 zuwa 12 blisters tab.).
• polymeric ganga 100 Allunan.

Tablet "Aspekard" ya ƙunshi 100 MG na ASA, microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, stearic acid.

Yabo don ganawa

A shirye-shiryen "Aspekard" aikace-aikace ne kunkuntar isa, ko da yake da shi ya ƙunshi umarnin ga shawarwari domin lura da yawa cututtuka, ciki har da rheumatic cututtuka. Manufacturer shawarar "Aspekard" da kuma matsayin antipyretic wakili ko analgesic. A gaskiya, a sashi na acetylsalicylic acid magani za a iya yadda ya kamata amfani da wani magani da cewa ya hana platelet tari.

Alamomi "Aspekard"

A cikin shirye-shiryen "Aspekard" wa'azi a kan aikace-aikace, sake bitar asibiti bincike kwararru da kuma ba mai yawa bayanai alaka antiplatelet far. An nuna a cikin wadannan yanayi:

• a lokacin da (ACS), m jijiyoyin zuciya ciwo (a mataki m tadawa tsokar zuciya infarction, ciki ko m ST kashi wuri, a m angina).
• tare da bugun jini (ischemic bugun jini ko dõgẽwa ischemic hari).
• idan na tabbatar da jijiyoyin zuciya jijiya cuta a matsayin wajen rigakafin m jijiyoyin zuciya ciwo da kuma bugun jini.
• a cikin rigakafin maimaita aukuwa daga m jijiyoyin zuciya ciwo da kuma bugun jini.
• da gaban varicose veins.
• kamar yadda wani m wakili, wani gargadi shunt thrombosis bayan CABG.
• tare da hauhawar jini a cikin hali na wani babban zuciya da jijiyoyin jini hadarin.

High zuciya da jijiyoyin jini hadarin shi ne wani tara ra'ayi da ya hada gaban manufa Gabar lalacewa a hauhawar jini da kuma alaka da cututtuka: ciwon sukari mellitus, jijiyoyin zuciya jijiya cuta, TSVB.

Features sashi regimens shawarar da manufacturer

A shirye-shiryen "Aspekard" m wa'azi da shi ba da babban jagorancin haƙuri da magani. Ya ƙunshi bayani game da gwamnatin da miyagun ƙwayoyi a daban-daban na asibiti yanayi jere daga rigakafin atherothrombotic events in CHD da TSVB da kuma kawo karshen tare da m cuta na cerebral wurare dabam dabam da kuma zuciya. Wannan tsallake aka dauke ɓãta, kuma Unprofessional hali zuwa batu na kwayoyi da kuma su rakiyar bayanai kayan. Yana kuma Halicci da preconditions for taro bazawa na articles a cikin abin da shawarar dosages sãɓawa jũna.

Dosing regimens kan kasa da kasa shawarwari

Bisa ga kasa da kasa da jagororin ci gaba da Turai Community of Cardiology (QShortcut) da American Zuciya Association (AHA) da kuma saba da Ma'aikatar Lafiya, da halaye na aikace-aikace na acetylsalicylic acid ne kamar haka:

• a mataki gaggawa a lokacin m jijiyoyin zuciya ciwo ake bukata ba da haƙuri tauna da Allunan, 3 "Aspekard 100". Umurnai na amfani ne watsi, da kuma guda kashi na 300 MG.
• kullum cardiac ischemia (CHD) a m liyafar sanya daya kwamfutar hannu na 100 MG da yamma bayan abincin dare.
• tare da hauhawar jini marasa lafiya da babban hadarin da cututtuka na zuciya da rikitarwa, kazalika da venous varicose kullum soma da 100 MG (1 kwamfutar hannu) da yamma bayan abincin dare.

Wasu hanyoyi na Drug Administration "Aspekard" wa'azi QShortcut da AHA ba samar. Yana da muhimmanci a lura da cewa misali kashi "Aspekard" ne 100 MG na ASA. Domin rigakafin na sama cututtuka, daidai da umarnin QShortcut da AHA, amfani da kashi na 75 MG. Duk da haka, 100 MG sanya marasa lafiya bayan CABG su hana thrombosis na shunt. A wasu lokuta shi da shawarar a yi amfani 75 MG, Ina nufin adadin ASA, wanda ya samar da isasshen antiplatelet sakamako, kuma yana da mafi ƙarancin hadarin gastrotoxicity.

Har ila yau, masu sana'anta ba ya samar da muhimmanci bayanai a kan yarjejeniyoyin da miyagun ƙwayoyi. Bisa kididdigar da, kwatsam lõkacin fatara daga cikin hanyar 10.2% na m zuciya da jijiyoyin jini events. Kuma an same su bayan kimanin 10.6 kwanaki daga ranar soke ASA. Wannan lokaci ne da matsakaita da kuma nuna lokaci a cikin abin da daukacin jama'ar an rage platelet cyclooxygenase aiki. A sakamakon haka, da yiwuwar jini clots mayar. Saboda da miyagun ƙwayoyi dole ne a dauki tutur, yayin da nada wani antiplatelet wakili maimakon "Aspekard" bayyanar rikitarwa daga cikin gastrointestinal fili ake bukata.

Contraindications "Aspekard" shirye-shiryen

Da lafiyar duk pharmaceutical kayayyakin ne dangi, domin suna da illa. A lokaci guda sun sa wasu contraindications. A musamman:

• a cuta daga jini coagulation (hemorrhagic diathesis, hemophilia A da B).
• a cuta daga ciki siffofin (erosions, m ulcers na ciki da kuma duodenum 12);
• a lokacin farko da trimester na ciki da kuma lactation.
• a mai tsanani na koda ko hanta hanawa.
• a lokacin da rashin lafiyan halayen ga salicylates.
• a cikin yara, matasa, fiye da shekaru 18.
• a gaban Bronchial fuka.
• da magani daga methotrexate.

Wadannan contraindications ne cikakkar, ko da yake wasu lokaci: lactation, ciki, yashewa da kuma ulcers na gastrointestinal fili, reno ina qarami. Kuma ma akwai wani rukuni na jihohi, da gaban wanda bukatar m monitoring da wani likita. Wannan lokaci daya amfani da antiplatelet far da anticoagulants, da kuma lura da marasa lafiya bayan jijiyoyin zuciya jijiya kewaye tiyata. Idan koda aiki amfani da miyagun ƙwayoyi "Aspekard" umarnin don amfani da bukatar sashi rage ko kammala sauka a hankali yarjejeniyoyin da miyagun ƙwayoyi.

Hadin gwiwa effects "Aspekard"

Acetylsalicylic acid na da yawan effects cewa bunkasa ko depress da mataki na dama kwayoyi. A musamman:

• ASA kara habaka sakamakon wani anticoagulants da antiplatelet jamiái.
• ASA kara habaka antipyretic da analgesic sakamako na NSAIDs, Yanã shimfiɗa antirheumatic sakamako "Meloxicam".
• a lokacin da a hade tare da cytotoxic kwayoyi kara habaka su gastrotoxicity.
• idan dauka tare da barasa hadarin miki rikitarwa ko zub da jini ƙaruwa.
• glucocorticoids karuwa gastrotoxicity "Aspekard".
• ACK attenuates diuretic sakamako a lokacin da a hade tare da diuretics "Furosemide", "torasemide", "spironolactone".
• "Aspekard" raunana sakamako na uricosuric jamiái, "Probenecid", "Etamid", "sulfinpirazon".
• nonabsorbable antacids rage sha na "Aspekard".

Yiwuwar wani yawan abin sama da kuma ta bayyanar cututtuka

In mun gwada miyagun ƙwayoyi "Aspekard" wa'azi, feedback da kuma yin amfani da statistics tabbatar da wani babban isa matakin tsaro a liyafar bisa ga alamomi da kuma contraindications togiya. Wannan yana nufin cewa wajabta kashi na 100 MG na da miyagun ƙwayoyi ne hadari isa, ko da yake iko da jiha na kiwon lafiya shi ne dole. Haka kuma, a cikin ra'ayi na Gungu da marasa lafiya da kunar nufi, kazalika da hadarin da allunan ASA zai ɗauki ɗan yaron, daki-daki bukata yiwuwa yawan abin sama da kuma ta bayyanar cututtuka.

M guba salicylates, tsokane ta aikace-aikace na cikin shirye-shiryen "Aspekard" ba tare da wani likita shawarwari cututtuka su ne cikin wadannan jihohi: dizziness, zafi a cikin fossa podlozhechkovoy, da cibiyarki yankin, wani lokacin zafi, musamman a cikin marasa lafiya tare da koda cuta. A hali na yawan abin sama kamar yadda a can ne rawan jiki, amai, wani lokacin da na jini zane. Na farko shi ne via da wucin gadi shigar da na emesis: m sanyi sha, kunna gawayi Hanyar da ehnterosorbentov bayarwa haƙuri a wani asibiti.

Muhimmanci, da mai guba allurai "Aspekard" umurci manual ba ya saka. Su ne daban-daban domin daban-daban nauyi da kuma shekaru na haƙuri. Alal misali, a cikin wani adult adam yawan abin sama m bayyanar cututtuka ASA faruwa a guda m game 5-7 grams acid. Yara da isasshen ga wani yawan abin sama da 1.5 g guda kashi. A babba yawan abin sama faruwa a lokacin da ake ji 7-9 grams na manya da yara 2-2.5 gram ASA.

Wannan mataki na miyagun ƙwayoyi yawan abin sama bayyana ta sama cuta shafe fahimi ayyuka. Rasa rubutu fara tinnitus tunani ta wãyi rikita, incoherent magana. Amai sau da yawa ya faru, da haƙuri da sauri hasarar ruwa daga amai, numfashi rãyar, akwai m urinary riƙewa, ya karu yanayin jiki. Taimaka wa haƙuri a cikin irin wannan halin da ake ciki ba shi yiwuwa a kansa - bayarwa ake bukata a cikin NICU ga jiko far bicarbonate, sodium lactate.

Features na warkewa mataki "Aspekard"

A haɗe zuwa da miyagun ƙwayoyi "Aspekard" aiki umurci hada da wani nuni ne na liyafar na daya kwamfutar hannu da rana (100 MG / rana). Wannan kashi ASA ya isa ya hana platelet cyclooxygenase. A sakamakon haka ne hanawa na kira na thromboxane A2, wanda gaba daya damuarn da ikon na sel zuwa platelet tari. Wannan gusar da yiwuwar thrombosis, wanda shi ne dalilin tsokar ko cerebral infarct.

Don samar da antithrombotic sakamako na acetylsalicylic acid ya kamata a tunawa a cikin jini. Duk da haka, wasu daga shi abubuwa a ciki da kuma ma inhibiting cyclooxygenase-1 da kuma ta isoforms a cikin mucosa daga cikin sashin jiki. A sakamakon wannan ginshiki ne gefen sakamako - rage ikon muco-shãmaki carbonate. Wannan qara kasada na erosions kuma ulcers daga cikin ciki, stimulates gastrointestinal-zub da jini. Enteric formulations ne ma iya sa jini, amma da mita daga wannan gefe sakamako, suna da musamman kananan.

Pregnancy kuma lactation

Gwani ra'ayi, dangane da ilimin kididdiga kimantawa da kuma jerin gwaje-gwajen, kyale ka ka yi wani fahimtar aikace-aikace na "Aspekard" da miyagun ƙwayoyi a lokacin daukar ciki. A musamman, 1 trimester ta yin amfani da aka haramta. A 2 da 3 trimester aikace-aikace da aka jiyar da, amma bayan kimantawa da warkewa amfani da gwama liyafar kasada. A mafi yawan asibiti yanayi nada ASA unnecessarily, ko da yake wasu NSAIDs ma iya kara hadarin ashara.

A lokacin lactation, yi amfani da miyagun ƙwayoyi "Aspekard" analogues shi, generics, kazalika da dukan magunguna da acetylsalicylic acid a cikin abun da ke ciki da aka haramta. Dalilin wannan shi ne ya buga da miyagun ƙwayoyi a nono. Yana ratsa ko da tare da shi a cikin baby ta jiki. Kuma ta hatsari ne babban hadarin da bunkasa Reye ta ciwo - musamman mai tsanani hanta encephalopathy, wanda ya haddasa kwakwalwa kumburi da kuma mutuwar wani yaro. Domin irin wannan dalilai, haramta yin amfani da miyagun ƙwayoyi kafin shekaru 16-18 shekaru.

Bayani dalla-dalla Reviews kwararru da kuma marasa lafiya

Characterizing da miyagun ƙwayoyi "Aspekard" haƙuri feedback a lokuta da dama son zuciya ba. Su ma kiyasta farashin da miyagun ƙwayoyi, tun da shi ne kusan mafi ƙasƙanci daga takwarorina. Duk da haka, comments shafi cikin m aikace-aikace na kasa nuni da rashin tantance digiri na marasa lafiya rage hadarin jijiyoyin bugun gini thrombosis. A cikin sharuddan illa ya ruwaito ta hanyar marasa lafiya, da miyagun ƙwayoyi ne halin a matsayin isasshe lafiya.

Ra'ayin masana bayyananne ne: da farko, da miyagun ƙwayoyi ne tasiri a rage hadarin thrombosis, kuma abu na biyu, marasa lafiya riko ga antiplatelet far ne mafi girma saboda low "Aspekard" farashin da miyagun ƙwayoyi. Analogs na aji na antiplatelet jamiái ne muhimmanci mafi girma. Domestic enteric shiri "Atsekardol" mafi tsada da 50%, yayin da kudin da shigo da hakan ta 7-10 sau. Amma dangane da m illa enteric jamiái, kazalika da tattalin arziki binciken, yana da kyawawa don ba da fifiko ga "Atsekardolu". A kudin wata-wata magani zai zama game da 20 rubles.

A haƙiƙa rashin kardiopreparata "Aspekard"

A haɗe zuwa da miyagun ƙwayoyi "Aspekard 100" umurci manual ce da miyagun ƙwayoyi ne samuwa a Allunan. Sun soke a ciki da kuma samar da wani babban taro. Samar da gida gastrotoksichesky sakamako, da miyagun ƙwayoyi hasarar Safety Sauran kwayoyi, wato enteric. ciki na jini hadarin lokacin da ake ji da karshen ne da yawa kasa.

Misalan mafi aminci kwayoyi su ne kamar haka: "Atsekardol", "Polokard", "Cardiomagnyl", "asfirin Cardio." Bugu da ƙari, ya ce wajen ma sun dauki magnesium hydroxide, iya kare mucosa daga rauni da acetylsalicylic acid. Duk da haka, da miyagun ƙwayoyi "Aspekard" za a iya amfani da rigakafin thrombus samuwar, albeit tare da hane-hane. Duk da haka, marasa lafiya da ciwon mucosal yashewa, miki 12 duodenum ko ciki, ciki har da kullum, shi ne shawarar ya dauki enteric kardioformy acetylsalicylic acid.

Vneotraslevoe aikace-aikace kardiopreparata "Aspekard"

Mafi yawa daga cikin samuwa umarnin don yin amfani da nuna gaban antiinflammatory da antipyretic Properties miyagun ƙwayoyi "Aspekard 100". A gaskiya, da cikakken magani yana da warkewa effects ne 5 sau da guda kashi - 500 MG. A sashi na 100 MG ne na musamman cardiac, kuma ta sakamako ne ba su isa ba, yadda ya kamata rage yawan zafin jiki a cututtuka.

Kardioforma shiri kerarre a kashi na 100 MG, shi ne dace da zafi da zazzabi taimako kawai tare da guda kashi na 5 Allunan. Kamar wancan predominance selectivity for cyclooxygenase 1 kayyade kasancewar wani jam'i na gefen halayen. Saboda haka, a matsayin febrifuge "Aspekard" kwayoyi, ba shakka, su dace. Duk da haka, a wannan lokacin da akwai da dama da dama mafi aminci kwayoyi exhibiting mafi girma selectivity for cyclooxygenase 2. Su ma sun m illa hade da take hakkin da yaduwa na gastrointestinal epithelium.

Safety aji takwarorinsu "Aspekard" miyagun ƙwayoyi

A irin wannan Trend aka lura da magani daga rheumatic cututtuka. Kuma a haɗe zuwa da miyagun ƙwayoyi "Aspekard" wa'azi ga yin amfani ƙunshi bayani game da su magani. Duk da haka, da shawarar kashi ne na tsari na 5-8 grams per day.

Wannan adadin acetylsalicylic acid nuna gastrotoxicity incomparably karfi sakamako fiye da lokacin da "meloxicam" Pharmaceuticals, "celecoxib", "Roferoksib" da sauransu. Kuma kamar yadda antipyretic mafi muhimmanci da aji analogue ne "Ibuprofen".