PTH ya karu - la'akari da matsayin da bincike?

Parathyroid hormone (in ba haka ba ya kira parathyroid hormone, parathyrin) - a hormone samar da parathyroid nama (parathyroid) gland, wanda aka located a kan anterolateral gefe na wuyansa. Su ne bayan da thyroid gland shine yake, wanda shi ne a hankali m zuwa ga raya surface gare su, kuma ƙananan bangare na biyu da rabo. Parathyroid hormone a cikin sinadaran halitta ne mai hadaddun gina jiki abu - polypeptide amino acid Kalam.

Its main aiki ne su shiga da kuma tsari na alli da phosphorus metabolism a cikin jiki. Da abun ciki na alli a jini da mugunya parathyroid hormone ne kai tsaye dogara daga juna. A hormone zai iya ƙara alli taro da aiki a kan kashi nama, koda da kuma gastrointestinal fili. A kashi parathyrin qara logoff rushe ma'adinai part ta haramta motsa kira na musamman enzymes da suke da alhakin rashin lafiya na kashi abu. Kashi nama ne hõre ƙarƙashin rinjayar PTH resorption da alli ions suna located a cikin jini. Tare da alli musayar paratgormot taimaka wajen tsara da matakin na phosphate a cikin jiki. Rage tsanani na farko nazarin halittu tsari, shi Yanã shimfiɗa biyu kwarara. Bugu da ƙari, hormone ne da hannu a inganta kira na calcitriol a cikin hanji, taimaka alli reabsorption. Parathyroid hormone daukan wani kai tsaye ba bangare a cikin tsari na ayyukan duk alli-dogara enzymes katalirizuemye su dauki. Ƙarƙashin ikonsa kuma samun jini coagulation tsarin.

Idan PTH aka dagagge, sa'an nan a kafa mai tsanani endocrine cututtuka hade da kashi mutunci take hakkin - hyperparathyroidism, da kuma osteoporosis. A sakamakon irin wannan physiological aibi sharply rage-rage a cikin jini alli matakan, wadda take kaiwa zuwa ƙãra neuromuscular excitability. Comorbidities a cikin wannan hali zai iya bauta wa high Alkali abun ciki a cikin jiki da kuma ci gaban da na koda gazawar. By rage abun ciki na alli a ruwan tabarau cataract idanu faruwa.

Matakan na hormone na parathyroid gland a cikin jini ne batun da circadian kari. A muhimmi matakin da aka kafa a game da 8 na safe, yayin da a cikin 14-16 sa'o'i na rana, a lokacin da wani mutum ne a ganiya na aiki, parathyroid hormone karu. jini gwajin da aka za'ayi da yawan parathyrin immunohemilyuminestsentsii. Yana dole ne yin komai a ciki, tare da rana ko biyu kafin jini Samfur kashe barasa ci da mãsu nauyi, motsa jiki na sa'o'i da dama kafin a hanya, kada shan taba.

A bincike na parathyroid hormone An wajabta kawai a lokacin da wani haƙuri ne da ake zargi da wanzuwar cututtuka irin hyper- da gipokaltsimiya, urolithiasis da neurofibromatosis. Har ila yau alamomi for analysis nufi iya sun hada da: osteoporosis psevdoperelomy dogon kasũsuwa, ashe, wani physiological canjãwa osteosclerosis kashi ko vertebral jikin da ake zargin mahara endocrine neoplasia irin 1 da kuma irin 2 (MUTANE 1.2). A parathormone kudi ga ya fara tasawa yana dauke 9,5-75 shafi / ml. Wannan ya shafi maza da mata da haihuwa shekaru. Idan gano cewa PTH aka dagagge, akwai kowane dalili ya ɗauka cewa haƙuri yana da farko, na biyu, manyan hyperparathyroidism, pseudohypoparathyreosis ko Zollinger-Ellison ciwo.

A karkashin hada farko hyperparathyroidism hyperplasia na parathyroid gland shine yake, ciwon daji na prostate nama da kuma endocrine neoplasia iri biyu. Co. sakandare hyperparathyroidism hada da kullum na koda insufficiency, hypervitaminosis D, ulcerative colitis, rickets, Crohn ta cuta. Idan PTH aka dagagge, sa'an nan da bincike mafi yawa ana yi a tare da tare da definition na matakin na alli a cikin jini, kuma a nan gaba da kwatanta biyu Manuniya da kuma gano dependencies.