"Heparin" (injections): aikace-aikace, mai amfani, da sake dubawa, kashi. A amfani da injections "Heparin" a lokacin daukar ciki

Drug "Heparin" shi ne iya rage da jini ta ikon gudan jini. Sakewa medicated wakili a gilashin ampules kuma vials na 5 ml. Su injectable bayani, cikinsa da aiki abu ne 5,000 Iu.

pharmacological Properties

Drug "Heparin" (injections) ne anticoagulant. Shi ne iya rage aiwatar da fibrin samuwar, rage gudu dalilai na jini coagulation, da kuma a cikin manyan yawa - don rage aiki na thrombin. Har ma da kananan allurai da miyagun ƙwayoyi ne isa ya kara fibrinolytic aiki na jini.

yin amfani da "Heparin" injections don rage danko na Babban jiki na nazarin halittu ruwa. Amfani da (wani kashi ga allura ance da likita akayi daban-daban) kahu a kan gaskiyar cewa wannan yana nufin an tara a endothelium na jini Kwayoyin kuma ƙara musu korau cajin. Saboda wannan dukiya rage-rage mannewa da kuma tari na platelets, leukocytes da erythrocytes.

Bugu da kari, da "Heparin" ya hana ci gaban atherosclerosis, yana da anti-rashin lafiyan da m vasodilator sakamako. Wannan shi ne saboda da cewa shi ya danganta da yawan abubuwa na dace da tsarin da kuma rage aiki. Har ila yau, da miyagun ƙwayoyi ya hana samuwar immunoglobulins, lymphocyte co ta ɗaure histamine da serotonin.

alamomi

Kamar yadda wani janar mulki, idan kana da matsaloli tare da jini clotting rubũta injections "Heparin" miyagun ƙwayoyi. Injections ko igiyar jini jiko bada shawarar a cikin wadannan lokuta:

1) zurfi jannayẽnsa thrombosis, jijiyoyin zuciya jijiya cuta, na huhu embolism.

2) tsokar zuciya infarction.

3) m angina.

4) A rukunin farko na DIC.

5) atrial fibrillation, wanda yana tare da thromboembolism.

Har ila yau a cikin asibitoci domin gudanar da extracorporeal wurare dabam dabam dabaru iya sanya nufin "Heparin". Injections intravenously ko subcutaneously, idan ya cancanta suke jini, hemodialysis su hana coagulation da nazarin halittu ruwa.

A wajen amfani domin lura da rigakafin cuta na microcirculation da microthrombogenesis, misali, thrombosis na koda veins, lupus nephritis, glomerulonephritis, kwayan endocarditis, mitral cututtukan zuciya, gemolitikouremicheskom ciwo.

sakamako daga cikin miyagun ƙwayoyi

Idan kana wajabta injections "heparin" a cikin ciki, ku sani: za su yi sau da yawa sosai. Effect da miyagun ƙwayoyi auku hanzari, amma shi ne takaice. Saboda haka, a lokacin da gudanar intravenously nufin clotting slows saukar kusan nan da nan, da sakamako yana game 4-5 hours. Lokacin gudanar intramuscularly, tasirinta bayan 15-30 minti kuma yana for 6 hours, da kuma lokacin da allura karkashin fata ne lura bayan 40-60 minti kuma yana 8 hours. Warkewa mataki da nufin hana samuwar jini clots, yana tsawon yawa.

Shiri "Heparin" qara koda jini ya kwarara, qara jijiyoyin bugun gini juriya a cikin kwakwalwa, yana da hypolipidemic sakamako. Bugu da kari yana nufin rage aiki na huhu surfactant damuarn wuce kima kira na aldosterone a cikin adrenal bawo, Yanã shimfiɗa aiki tasiri PTH ta ɗaure adrenaline.

amfani Features

Sau da yawa mutanen da fama da jijiyoyin zuciya da cututtukan zuciya, rubũta "Heparin" (Shots). Farashin wannan magani alama high zuwa wasu. Marufi da 5 ampoules na 5 ml tare da wani aiki na 5000 Iu da 1 ml kudin 500-600 rubles. Amma to ki da aikace-aikace ne ba zai yiwu ba. Bayan duk, a cikin marasa lafiya da ischemia nufin "Heparin" rage hadarin na tsokar zuciya infarction, jijiyoyin zuciya jijiya thrombosis kuma kwatsam mutuwa. Haka kuma, amfani da miyagun ƙwayoyi iya rage yiwuwar maimaita zuciya harin da rage yawan mutuwar a wadannan marasa lafiya.

Lokacin da venous thrombosis da na huhu embolism rubũta high kashi "Heparin" shirye-shiryen. Injections (umurci damar magance yadda ya kamata sa su) suna sanya a wani lokaci. Amma, shi ne gaskiya, a wasu lokuta, kafin su sami nan da nan sakamako ne ake so a tafiyad da igiyar jini wajen.

Har ila yau rubũta a wajen "Heparin" don rigakafin thromboembolic events, kamar bayan tiyata. A wannan yanayin, shi an wajabta, a kananan allurai.

Hanyoyin da yin amfani da

Select da ake bukata sashi da kuma Hanyar yin amfani da miyagun ƙwayoyi ya kamata kawai likita, dangane da haƙuri da yanayin da kuma dalilan da ya sa ya na bukatar wannan magani. Agent iya gudanar intravenously a matsayin ci gaba da jiko ko yau da kullum injections. Har ila yau, a wasu lokuta, subcutaneous, ko za a iya nada ta intramuscular allura.

Don hana thrombosis miyagun ƙwayoyi iya gudanar subcutaneously da 1 ml (5000 Iu) sau biyu a rana. A cikin larura na wannan fassarar ne a haɗe zuwa da miyagun ƙwayoyi "Heparin" umurci manual. Injections yawanci sanya a ciki, a cikin anterolateral bango. Don yin wannan, kai mai lafiya allura da kuma allurar shi zurfi a cikin fata Musulunci. An kafa a lokacin da aka tara tsakanin yatsa da kuma forefinger na ciki yankin a cikin cibiya yankin. A allura dole ne a alternated. A kwarai lokuta, da injections za a iya yi a cikin sama ɓangare na cinya ko babba hannu.

sashi selection

Domin warkewa dalilai cikin sharuddan inpatient magani a asibitoci sukan wajabta igiyar jini jiko. Domin adult marasa lafiya, da sashi na 1,000 Iu / hour. Amma kafin installing drip ga iyakar sakamako shi zai iya shigar da bolus cikin wani jijiya a cikin adadin 5,000 Iu. Selection na daidai kashi da aka gudanar a wani likita dangane da halin da ake ciki da kuma haƙuri da nauyi.

Idan ba shi yiwuwa a gudanar da wani igiyar jini jiko, da jamiái iya gudanar subcutaneously: 2 ml da miyagun ƙwayoyi (wanda yayi dace 10000 Iu) 4 sau per day. Matsakaicin sashi ne kullum amfani da shirye-shiryen zuwa kwanaki 10.

The bukata adadin da miyagun ƙwayoyi ne a zabi bayan da kimantawa gwajin sakamakon. Musamman hankali ne ya biya zuwa APTT (kunna m thromboplastin lokaci).

Lokacin da mai bayarwa jini, ana kullum gudanar 7.5-10 dubu. Iu nufin "Heparin".

Far a lokuta na musamman

A m tsokar zuciya infarction nan da nan gudanar 10-15 dubu. Iu intravenously, sa'an nan ta ci gaba da yin amfani da irin wannan lissafi, da mãsu haƙuri samu game da 40 000 Iu a rana ta farko, amma da ainihin sashi aka zaɓi dangane da haƙuri da nauyi. Wannan wajibi ne a tabbatar da cewa jini clots a 2.5-3 sau hankali. Daga rana ta biyu da kashi ne rage. Yana da muhimmanci cewa clotting lokaci ne 1.5-2 sau fi da kullum. Jiyya tare da wannan magani ya ci gaba da 8 kwanaki. Don soke wani kullum kashi rage by 5-10 dubu. Iu, amma jinkiri tsakanin injections kada Ka ƙãrã. Bayan da yarjejeniyoyin da izinin ga anticoagulants na kai tsaye ba mataki. Yana iya zama irin wannan hanyar a matsayin "Fenilin", "neodikumarina" da sauransu.

M jijiya ko venous toshewa ma bukatar wani musamman m. Domin lura wajabta igiyar jini heparin for 3-5 days a kashi na 400-450 Iu da kg na haƙuri nauyi. Wannan shi ne, a haƙuri na matsakaici ginawa da kuma tsawo ya kamata a sami wani yini game 30-40 dubu. Iu "Heparin" miyagun ƙwayoyi. Sa'an nan matsa wa fractional da gabatarwar, amma da sashi ne ta ƙara zuwa kimanin 600 Iu / kg, tare da guda allura a cikin jiki ya kamata a sami 100 Iu / kg. Jiyya iya wuce har zuwa 16 days. A kawai 'yan kwanaki kafin miyagun ƙwayoyi karbo adadin da aka hankali rage. Jiyya da aka ci gaba ta amfani da kaikaitaccen anticoagulants.

tsõratar

Duk da cewa wasu magana game da yiwuwar intramuscular allura daga cikin miyagun ƙwayoyi, wannan ba da shawarar saboda gaskiyar cewa a allura site hematoma sau da yawa kafa. Don amfani da miyagun ƙwayoyi dilutions 0,9% NaCl bayani.

Yana da muhimmanci a san cewa a lokacin da magani daga "Heparin" na nufin ba lallai ba ne don yin wani intramuscular allura da kuma biopsy gabobin. Lokacin amfani da shi, kana bukatar ka saka idanu da jihar coagulation. A cikin makon farko na far, jini bari kowane kwana biyu, fara daga mako na biyu shi za a iya yi a kowace 3 days.

Ko da yake wajen da kuma ba ya shiga cikin nono madara, lactation a lokacin jiyya, shi ne kyawawa su karbi. An gano cewa da miyagun ƙwayoyi take kaiwa a wasu lokuta zuwa ga lalata kashin baya da kuma osteoporosis. The matsaloli fara bayan 2-4 makonni na magani.

Dabam, shi ne ya kamata a lura da cewa da miyagun ƙwayoyi bayani iya fatsifatsi, amma tana da wani sakamako a kan ta pharmacological Properties ko haƙuri nufin "Heparin". Injections, farashin wanda zai iya muhimmanci shafi kasafin kudin a nada shi a high allurai, za a iya yi ko da a kan nasu a gida.

contraindications

Kamar wani wajen, ba za ka iya amfani da miyagun ƙwayoyi "Heparin" idan kai ne hypersensitive. An ba da wajabta wani zub da jini. Ban ne hemorrhages cewa faruwa a lokacin da tsokar huhu (da aka bayyana a cikin hanyar hemoptysis) ko koda (tare hematuria).

Contraindications kuma sun hada da:

- hemorrhagic diathesis da kuma sauran cututtuka a wadda illa jini clotting.

- ƙara jijiyoyin bugun gini permeability, kamar Verlgofa cuta.

- kwayan endocarditis .

- zub da jini a tarihin;

- hypoplastic da aplastic anemia, na kullum da kuma m leukemias.

- tsanani hanta da koda aiki.

- venous gangrene.

- ci gaban da m zuciya aneurysm.

rigakafi

Bugu da kari a kai tsaye contraindications, akwai jerin yanayi a cikin abin da shi wajibi ne don kimanta duk wani hadari a lokacin da shan "Heparin" miyagun ƙwayoyi. Injections da kuma igiyar jini yi sai a lokuta da kuma karkashin kulawa na kwararru a marurai ulcerative raunuka na gastrointestinal fili, hawan jini, zubar da postoperative zamani, fãce angioplasty.

A 'yan kalmomi game da magani daga gaba uwãyensu ne. Duk da cewa jiyya na mata a cikin iyali hanya kafin mu nufin a ke so (shi za a iya kai wa ga ci gaban da rikitarwa), injections "heparin" a cikin ciki an wajabta, a wasu lokuta, a lokacin daukar ciki. Yiwuwar faru na illa jere daga 10 zuwa 21%. Duk da yake ga al'ada ciki hadarin rikitarwa shi ne kasa da 3.6%.

Ya kamata a lura da cewa sakamakon wani yiwu thromboembolism a expectant uwãyensu ne mafi hatsari a rayuwa fiye da samun nufin "Heparin". Injections a lokacin daukar ciki yi kawai a karkashin likita dubawa kuma kawai idan akwai cikakkar shaida. Amma da miyagun ƙwayoyi zai iya sa jini, thrombocytopenia da kuma osteoporosis. Yana nufin mahaifa ba ya shiga.

Zai yiwu analogs da haƙuri shedu

Sau da yawa wadanda aka nada miyagun ƙwayoyi "Heparin" (injections a ciki), da farashin da alama ma high. Amma idan aka yi amfani da matsayin m gwargwado, 1 kunshin iya Wadãtar da 'yan kwanaki. Saboda haka, marufi a cikin abin da kwalabe 5, yana iya zama isa ga wani mako biyu. A high-kashi shiri da ake amfani da yawanci ba fiye 10-14 kwanaki.

Duk da haka, da yawa mutane suna so su koyi daga sauran marasa lafiya, yana da daraja sayen magani, suna neman "Heparin" shiri na sake dubawa. Analogues da miyagun ƙwayoyi suka kuma suna sha'awar. Saboda haka, idan akwai matsaloli tare da jini clotting, da kayan aiki sosai tasiri da kuma ba ka damar cimma da ake so warkewa sakamako sosai da sauri. Wannan ya tabbatar da duka biyu likitoci da kuma marasa lafiya.

Amma maimakon ta iya sanya anticoagulants "Troparin", "Heparin Sandoz", "Heparin sodium Brown", "Heparin-Verein" da sauran analogs. A sashi na wadannan kwayoyi kamata kawai zabi wani likita dangane da sakamakon da ƙididdiga na haƙuri, jihar ya kiwon lafiya da kuma alamomi ga wanda da miyagun ƙwayoyi An wajabta.

A wasu lokuta, likitoci bayar da shawarar low kwayoyin nauyi heparins, kamar "Fraksiparin", "Fragmin", "Tsibor", "Eniksum", "Fraksiparin forte." Su sakamako, kamar yadda evidenced da martani da marasa lafiya, kusan guda a matsayin cewa daga cikin miyagun ƙwayoyi da mu.