Hla bugawa

The gaggawa na matsaloli kamar ashara da kuma rasa haihuwa, yanzu ƙara girma. Rushewa daga cikin aiki da haihuwa gabobin da namiji da mace al'aura tsarin kai ga kama jihohi.

Daga cikin dalilan ne don samar da duka biyu haihuwa lahani kuma samu (cututtuka, cuta na endocrine ayyuka, immunological matsaloli). An samo pathological yanayin sau da yawa amsa wa jiyya, wanda ba m (genetically) canje-canje.

A halin yanzu, da samun saurin bunkasuwar dabara na a vitro hadi, amma wannan hanya ne ba ko da yaushe tasiri da wuya nuna da ake so sakamakon.

Yau, masana kimiyya sun ƙarasa da cewa mafiya yawa daga kasawa a cikin vitro hadi ne Hla-dace. Hla-incompatibility tsarin maza take kaiwa zuwa gestosis a lokacin daukar ciki, haihuwa lahani, maras wata-wata abortions da kuma rasa haihuwa ainihin mata.

Hla-tsarin ne ba wani abu ba fiye da histocompatibility antigens, wanda ke da alhakin amincewa da jikin mutum da kansa tsokoki da kuma kasashen waje Kwayoyin.

A cikin akwati inda gano take hakkin da antigenic abun da ke ciki na mutum Kwayoyin, da inji yana jawo su rigakafi halaka (rigakafi martani). Don waje antigens samar da m antibodies, wanda cire "rikici" Kwayoyin.

Wasu Hla-coding gene hade shida chromosome

Kowace daga cikin kwayoyin halittu yana da yawa daban-daban haduwa (alleles).

Hla-bugawa da aka yi domin sanin histocompatibility tsarin. Shi ne da katin shaida na alleles (bambance-bambancen karatu) da kuma shi ne sakamakon da bugawa.

All antigens za a iya raba biyu main azuzuwan. A farko yana dauke da surface antigens na Kwayoyin, na biyu - antigens yanzu a kan salula surface cewa shiga a immunological halayen (a nan su ne: B- da kuma T-lymphocytes, macrophages, monocytes, dendritic Kwayoyin).

Hla-bugawa da aka yi a kan shaidar mata. Daga cikin su akwai:

- ashara,

- rashin haihuwa da kuma sauran pathological yanayi hade tare da mai illa haifuwa.

Yadda aka saba, da yaro ya karbi duka biyu masu juna biyu da kuma na uba genes domin sanin abun da ke ciki na da nasu antibodies.

Pathological ne a matsayin kaifi, sãɓã wa jũnamai (bambancin) antibodies, kuma su magana kama. A cikin farko idan, uwar jiki farawa da in yaqi dan hanya tayin Kwayoyin, yayin da na biyu - wata mace ta jiki ba ya gane da daukar ciki da kanta.

Hla-bugawa na iyaye da aka gudanar da na biyu aji na antigens (rigakafi alhakin aiki). Don yin wannan bincike magudi wajibi ne don yin wani shinge na jini daga jijiyar na haƙuri. Daga bisani gudanar da kasafi na magani leukocytes. Hla-buga ta amfani da farin jini Kwayoyin domin samar da polymerase sarkar dauki.

A wannan yanayin, a lokacin da akwai wani kwatankwacinsa tsakanin phenotypes (a kan na Hla), aka gudanar da uwar immunization far tattara leukocytes miji (uban yaron). Bugu da ƙari kuma, immunotherapy ne da za'ayi amfani da immunoglobulin. Duk wadannan dabaru sa ya yiwu don kunna rigakafi da tsarin na da uwarsa da ta da ta dace aiki.

Saboda haka, Hla-buga a yau ne da za'ayi a taron na alamomi da wani take hakkin a histocompatibility mahaifiyarsa ta tsokoki da yaro. A amfani da wannan bincike Hanyar ya yarda ba kawai don gano dalilin ashara da kuma rasa haihuwa, amma ya ci gaba da aiwatar da dukan kewayon warkewa hanyoyin da dabarun ga nasara lura da wadannan pathological yanayi.