Phosphatidic acid. Kira kuma muhimmanci a cikin jiki

Daga cikin ra'ayinsa na sinadaran tsarin, phosphatidic acid ne mafi sauki phospholipid.

Wannan abu ne daya daga cikin turakun da phosphoglycerides metabolism a vivo.

Wannan aji na abubuwa ne da aka ba da yawa da hankali a cikin binciken na siginar ayyuka na sinadaran mahadi.

Don kwanan, har zuwa karshen ba share duk links a cikin metabolism na phosphatidic acid, musamman, har yanzu dauke da tambaya daga cikin ginshikai na siginar watsa bayanai sadarwa, kazalika da game da kasancewar phosphatidic acid ionophoric Properties.

Kira na phosphatidic acid

Phosphatidic acid samuwar ne ya rinjayi phospholipase D. Wannan aji na enzymes yana rawa wajen kira na phosphatidic acid. Kamar yadda mun gwada short-rayu sinadaran fili, baya cikin abu a ƙarƙashin rinjayar fosfogidrolazy hydrolysed zuwa diglyceride (ta dauki dephosphorylation).

Lokacin da hulda da wannan enzyme phosphatidic acid za a iya canza kama, kuma diacylglycerol, wanda ya aikata wani zagayowar daga biochemical halayen activator aiki na enzyme gina jiki kinase C.

Kira na phosphatidic acid faruwa a adipose nama. A tsari fara da rasit a adipocytes (adipose nama Kwayoyin) m acid kafa a cikin hydrolysis na fats (yafi, sosai low yawa lipoproteins). Ciki da cell, hulda da glycerol-tri-phosphate, m acid ana tuba farko zuwa lysophosphatidic acid, daga abin da baya kafa phosphatidic acid.

Formula kafa gare phosphoric glycerophospholipids dauke da sharan na m acid, glycerol, kuma nitrogen-dauke da anions.

Meaning of phosphatidic acid

An gano cewa phosphatidic acid ne da ake kira sigina sadarwa, wato, waɗanda suke a aiki na shamaki a watsa bayanai a yi sigina tafarkin. A musamman, shi ne a key mahada a watsa wadannan sakonni a shuka Kwayoyin:

• cytokinin.
• osmotic cewa yana da darajar a cikin ci gaban da wani salon salula mayar da martani ga wannan irin na danniya.

A lokacin gwaje gwajen da aka nuna da cewa matakin na fili a cikin Kwayoyin fallasa su shuka kwayoyin pathogenic dalilai qara muhimmanci. Wannan dauki sa:

• Osmotic danniya.
• Low yanayin zafi.
• A sakamakon wasu aiki sinadaran da ciwon kayan lambu asalin (phytohormones).

Saboda haka, shi za a iya kammala a hannu na phosphatidic acid da kuma ta metabolites a hadaddun halayen alhakin karbuwa da kwayoyin zuwa stressful yanayi.

Bugu da ƙari kuma, an san cewa phosphatidic acid yana da muhimmanci ga kai na protons kuma dauki alli ions ta cikin membranes na neurons da tsoka zaruruwa. Haka kuma, phosphatidic acid da kuma siffantãwa aiki ionophore (selectively: for alli ions da protons).

transduction inji

Ko da yake da manufar phosphatidic acid samu kai tsaye da hanyar (inji) da siginar watsa ne har yanzu muhawara da kuma bukatar jaddadawa.

Duk da haka babu wani shakka cewa transduction ne da za'ayi godiya ga ikon da phosphatidic acid, shafi salula tsarin da membrane, da membrane tsara da aiki na enzymes, da kuma shiga a cikin hulda da salon salula membrane sunadarai na gina jiki.

Aikace-aikace na phosphatidic acid

Nazarin yi aiki antioxidant na Kalam na phosphatidic acid, gudanar kamar yadda a cikin binciken na model matakai da kuma shafe nazarin halittu abubuwa sun nuna cewa abin da ake kira phosphatidic acid mimetics mallaka antioxidant jam'i na sunadaran da mataki.

M bayanai a kan shugabanci na mataki na phosphatidic acid damar yin amfani da shi da kuma ta metabolites a samar da ilimin aiki abubuwa tsara don inganta yi da kuma jimiri na sel.

Mukaddashin a kan salula matakin, irin mahadi ba ta da, amma kawai normalize Kwayoyin. lamari ne mai muhimmanci don rage girman hadarin da mummunan illa.