"Kosopt": umarnin don amfani, reviews. Analog "Kosopta" (ido saukad da)

Domin lura da cututtuka hade tare da wucin gadi ko m karuwa a matsa lamba a cikin eyeball, sakamakon wani karu a gani acuity kuma Game da jijiya atrophy, nema miyagun ƙwayoyi "Kosopt". Analogs da ciwon irin wannan mataki, zai iya zama madadin ga wannan wakili.

description

A miyagun ƙwayoyi ne samuwa a cikin nau'i na ido saukad da, kamar yadda ya hade antiglaucoma medicament for ragewan intraocular matsa lamba ta rage a saki ruwa mugunya a cikin jiki.

Da yake hadaddun a cikin halitta, saukad "Kosopt" a cikin tsarin da biyu aiki abubuwa. Daya daga cikinsu, dorzolamide hydrochloride ne ba a wani adadin 22.26 MG da 1 ml, daidai da 20 MG tushe dorzolamide. Na biyu aiki sashi ne timolol maleate a wani adadin 6,83 MG da 1 ml, wanda yake daidai 5 MG na timolol tushe. Don ƙirƙirar barga bayani da ake amfani, ƙarin abubuwa bayar ajiya domin shiri na da'awar shiryayye rai. Wadannan sun hada da: a 50% bayani daga benzalkonium chloride, sodium citrate, mannitol, hydroxyethylcellulose, sodium hydroxide bayani, distilled ruwa ga allura.

Shiri "Kosopt" ido saukad da, shi ne mai gaskiya, colorless ko kusan colorless, dan kadan danko sosai ruwa. Samar a cikin roba vials na 5 ml.

Ginshikai na mataki na nufin

Antiglaucoma sakamako dangane da sakamako na biyu aiki aka gyara: dorzolamide hydrochloride da timolol maleate. Kowace daga cikinsu rage intraocular ruwa mugunya, wadda take kaiwa zuwa rage darajar intraocular matsa lamba a al'ada. A sakamakon hada mataki na abun da ke ciki "Kosopt" halitta (ido saukad) umurci characterizes a matsayin mafi girma akan rage wannan siga.

Action dorzolamide hydrochloride dangane da zabe hanawa na carbonic anhydrase na ga II irin. Slow aiki na wannan enzyme rage mugunya na ciliary jiki ocular ruwa, wanda ake dangantawa da wani karu a cikin samuwar bicarbonate ions, inda hakan da kai daga sodium ions da ruwa.

A lokacin Topical gwamnatin dorzolamide hydrochloride shiga janar jijiyoyi. Tsawo amfani da wannan fili take kaiwa zuwa jari na ta kwayoyin cikin erythrocytic Kwayoyin. Wannan shi ne saboda da zabe nauyin da na biyu da irin tare da carbonic anhydrase dorzolamide hydrochloride, wadda take kaiwa zuwa wani karu a jini jini miyagun ƙwayoyi a free form. N ne metabolite na dorzolamide -desetilnoe wanda aka samu, wanda shi ne kasa pronounced tarewa ikon carbonic anhydrase biyu irin lokacin da idan aka kwatanta da mataki na asali siffar, amma watakila hanawa na carbonic anhydrase farko da irin. Metabolite jari ma na faruwa a erythrocyte Kwayoyin a mamaye fom da farko irin carbonic anhydrase.

Up to 33% na kwayoyin suna da alaka dorzolamide da jini albumin. Derivation na aiki sashi da kuma ta metabolites a fitsari aka yi. Karbo daga cikin miyagun ƙwayoyi take kaiwa zuwa maras mike dorzolamide kau na erythrocyte jini Kwayoyin. A farkon da jiyya, wani m rage na da abun ciki, sa'an nan cire aiki abu daga erythrocytes aka rage. Half-rai bayan instillation na dorzolamide "Kosopt" shiri umarnin don amfani da za su zama akalla 4 watanni.

Features na mataki na aiki abubuwa

Timolol maleate farfado da kaddarorin wani maras zabe beta-shafi. Its rawa a rage intraocular matsa lamba hade da wani karu a samar da ya karu intraocular m kau daga sarari.

Topical gwamnatin timolol maleate a cikin "Kosopt" saukad da take kaiwa zuwa ga shigar azzakari cikin farji daga cikin abu a cikin general wurare dabam dabam tsarin. A hypotensive sakamako na timolol fara minti 20 bayan gwamnatin, ta matsakaicin sakamako zo bayan 120 minti kuma kiyaye domin 1 rana.

alamomi

A farko nuni ga miyagun ƙwayoyi "Kosopt" (ido saukad) sigar bude-da pseudoexfoliation glaucoma da ãyõyin ƙara matsa lamba a cikin ido lokacin gaji da damuwa da outflow na intraocular ruwa. A mataki na medicament ne directed zuwa ta kawar da rage samar da danshi da cewa tara a cikin shirayin da ido, ya tura a kan na gani jijiya manyan zuwa ta m atrophy.

Yadda za a yi amfani da

Shiri "Kosopt" User Aikace-aikacen umurci tambaya 1 drop da conjunctival jakar kwai na haƙuri da idanu ko don rigakafin na biyu idanu a 2 sau per day.

Lokacin da manufar wannan magani ne da nufin maye gurbin baya amfani saukad daga glaucoma, suna bukatar su daina yin amfani da for 1 rana, sa'an nan watakila wani sabon wajen magani. The bayani "Kosopt" gudanar ba jima fiye da minti 10 bayan aikace-aikace na sauran Topical ophthalmic shirye-shirye.

Amfani da wannan kayan aiki na bukatar haƙuri yarda da musamman umarnin a lokacin da aiki tare da wani bakararre bayani. Kwalban "Kosopt" halitta (ido saukad) da shawara duba umarni kafin bude mutunci da tsaro tsiri.

Unopened vials ne gibba tsakanin hula da kuma cikin kwalbar. Don buɗe hula tsiri ake bukata don cire kariya daga bude.

Ga bude kwalban tafiya ne unscrewed a cikin shugabanci nuna ta directional kibiya, located a kan tafiya.

Kafin kai tsaye aikace-aikace na miyagun ƙwayoyi da haƙuri jefa mayar kansa, jan gefen ƙananan fatar ido, don nuna sarari tsakanin ciki surface na fatar ido da kuma eyeball.

Next inverted kwalban, ta amfani da babba dan yatsa da dole ne a hankali guga man a cikin wuri, musamman alama a kan surface na kumfa, cewa saki daya kawai drop of bayani a cikin shafa ido. Yana da unacceptable taba wuyansa na kwalba da eyeball, ko surface na karni. Rashin iya amfaninka na cikin kwalbar sa ido cututtuka daban-daban pathogens, wadda take kaiwa zuwa tsanani sakamakon da karin asarar hangen nesa.

Idan biyu idanu ne da lafiya, da sama-da aka bayyana magudi a cikin wannan hanya kamar yadda za'ayi tare da wani.

Bayan yin amfani ya zama tam dunƙule hula a kan kwalban, amma ba su da bukatar karfi latsa cover haka kada su lalata thread form. A bude a tip na spout yana da wani diamita wadda ke bayar da dosed da instillation bayani, don haka bai kamata ya fadada.

m halayen

An kyau-jure magani "Kosopt" (ido saukad), reviews bayyana gefe effects ne musamman rare. Lokacin da nazarin medicament a asibiti nazarin m halayen da suke na musamman domin wannan hade aka ba rubuta ba, amma an lura riga aka sani gefen sakamakon dorzolamide hydrochloride, timolol maleate kuma daga, amma wadannan cututtuka sun m cikin yanayi da ba ya bukatar an daina far.

Nazarin miyagun ƙwayoyi "Kosopt" a gwajinsu a kan mutum Hidima, a 1035. Don 2.4% na marasa lafiya ido saukad da za a soke saboda m halayen batu da ya bayyana a kan gabobi da hangen nesa. Yana tabbatar da ba zai yiwu ba ga magani 1.2% na masu sa kai da suka yi lura da gida illa hade da hypersensitivity kuma alerji.

A mafi m manifestations da aka kai tsaye alaka da gabobin da ganinsu. Sun nuna wani kona abin mamaki a cikin idanu, corneal yashewa, Heart hangen nesa, na ruwa idanu.

A haɗe zuwa da miyagun ƙwayoyi "Kosopt" (ido saukad) User aikace-aikace hada da wani bayanin yiwu m halayen da aiki aka gyara daga cikin miyagun ƙwayoyi bayani, wanda zai iya shiga cikin janar wurare dabam dabam.

Effect na dorzolamide hydrochloride a kan gabobin da hangen nesa da zai iya faruwa kumburi karni, hangula da peeling da fata a kan fatar ido, iridocyclitis, ma'ana keratitis, mai shudewa myopia. Wadannan canje-canje dauki sanya wasu lokaci bayan an daina lura da wannan magani.

Dorzolamide hydrochloride mataki a kan m tsarin alama ta da ciwon kai, dizziness, numbness na wata gabar jiki da numbness, tingling da kuma tingling na fata, gajiya, kuma asthenic ciwo.

Rashin lafiyan dauki iya faruwa a cikin hanyar angioedema fuska, extremities, urticaria, itching, Bronchial spasm, pharyngeal mucosa hangula, rashin ruwa a cikin baka rami.

A ke so effects iya bayyana dorzolamide hydrochloride epistaxis.

Lokacin gudanar da miyagun ƙwayoyi "Kosopt" illa daga daukan hotuna na timolol maleate da ido na iya faruwa kumburi a cikin mucosa da cornea, da ciwon kumburi ciliary baki karni, rage corneal ji na ƙwarai, bushe mucous gani acuity cuta, ruwan tabarau Refractive sosai idanu raba bayyane images , ptosis daga cikin manya fatar ido.

The aiki miyagun ƙwayoyi abu ne timolol maleate, kasancewa a beta a shafi na iya haifar da gefen halayen muhimmi a cikin wannan rukuni na abubuwa.

A mataki a kan zuciya da jijiyoyin jini tsarin ne halin da tinnitus, arrhythmia na zuciya tsoka da jini wurare dabam dabam, hawan jini, exacerbation na angina, vasospastic yanayi, aka rufe da mãgãgi, sakamakon bugun zuciya, nama edema, claudication, azanci shine cuta da numbness, tingling da kuma tingling a cikin fata, bayyanar cututtuka na Raynaud ta, sanyi hannuwansa da ƙafafunsa.

Topical gwamnatin timolol maleate sa tari da kuma bronchospasm, musamman mutane da ciwon bronhoobstruktivnogo Pathology.

Skin canje-canje sa da mataki na thymol, hade da gashi hasara, psoriasiform rash ko exacerbation na psoriatic raunuka.

Tun da rashin lafiyan halayen hade da bayyanar da anaphylactic buga, angioedema, urticaria, na gida ko kowa yana da kurji a kan fata.

Timolol maleate rinjayar da tsakiya m tsarin tare da bayyanar cututtuka na dizziness, ciki, barci cuta, memory asarar, gajiya striated tsoka.

Narkewa kamar abu ya haddasa zawo, illa absorbability, bushewa da mucous membrane na baka rami.

amfani Features

Assigning saukad "Kosopt", likita ya tabbatar a gaba da cewa babu wani gazawar da zuciya tsoka. Marasa lafiya da tsanani tsokar Pathology a baya, da alamu na rashin cin nasara a wannan lokacin, a lokacin jiyya a wannan magani ya kamata a lokaci-lokaci ya lura da wani likitan zuciyar da kuma saka idanu da zuciya rate. Tabarbarewar da zuciya bukatar nan da nan miyagun ƙwayoyi janye.

Akwai lokuta da mutuwa daga Bronchial spasm lalacewa ta hanyar timolol maleate saukad "Kosopt" a marasa lafiya da suke da fuka da kuma zuciya rashin cin nasara.

A tasiri daga cikin miyagun ƙwayoyi a kan mutane tare da hanta insufficiency, ba a karatu sai da taka tsantsan da ake bukata a lura da antiglaucoma jamiái.

Hargitsi na acid-balance tushe saboda da amfani da carbonic anhydrase hanawa na enzyme, wadda take kaiwa zuwa urolithiasis, wanda sau da yawa tasowa a marasa lafiya tare da urolithiasis a baya.

A lura da beta-blockers mutane da ciwon sukari ko da qarancin ruwa da yake a murdiya na wasu cututtuka halayyar da qarancin ruwa da.

Beta-blockers, smoothes ãyõyin hyperfunction na thyroid gland shine yake, da kuma yarjejeniyoyin da kayan aiki na iya worsen da yanayin.

Kafin mai zuwa tiyata ta amfani da janar maganin sa barci samar soke ido saukad da na kwana biyu kafin Jirgi hanya don rage tasirin timolol a tsoka relaxants da kuma janar anesthetics.

Kamar yadda wani ɓangare na "Kosopt" saukad akwai benzalkonium chloride, mukaddashin kamar yadda hana aifuwa na maza, wanda zai iya sa ido hangula. Lokacin amfani lamba ruwan tabarau tare da shirye-shiryen a gaba shi ne zama dole a cire da kuma sa on 15 da minti bayan gwamnati na bayani. A mataki na benzalkonium chloride zai iya sa discolouration na taushi lamba ruwan tabarau.

Side effects na amfani da miyagun ƙwayoyi wahalad da tuki ko ko management na hadaddun sunadaran.

hulda

Alli tashar blockers, beta-blockers, antiarrhythmics, Digitalis glycosides, kateholaministoschayuschie jamiái, parasympathomimetics, opioid analgesics, kuma monoamine oxidase hanawa a hade tare da ido saukad da na timolol maleate tushen nuna hypotensive sakamako da kuma sa bradycardia mafi har.

Tsari Beta-adrenoceptor kawancen hade da wani karu a zuciya rate, aka lura a cikin hulda da timolol maleate da quinidine ko zabe mai hanawa shafi cikin reuptake na serotonin.

Hulda da timolol maleate da epinephrine zai iya sa fadada daga cikin haƙuri na ƴan.

analogs

A manufacturer na asali droplet "Kosopt" ne Dutch kamfanin "Merck Sharpe & Dohme BV", a cikin abin da dakunan gwaje-gwaje na musamman tsarin domin idanu na biyu aiki abubuwa na bayani da aka kafa (dorzolamide hydrochloride da timolol maleate) da kuma karin aka gyara. Wannan kayan aiki da ya samu m aikace-aikace da magani daga glaucoma.

Romanian Pharmaceutical kamfanin "KO Rompharm Company SRL "da aka ɓullo da analogue" Kosopta ", sanar da ingantaccen da kuma gwada yawa abun da ke ciki na aiki aka gyara na asali. Dukansu formulations aka kerarre a cikin nau'i na ido saukad da, ainihin abinda ke ciki na dorzolamide hydrochloride a cikin bayani a cikin wani adadin 22.26 MG da 6,84 MG na timolol maleate, amma akwai kadan bambanci a cikin karin aka gyara. Samuwa analogue "Kosopta" a karkashin cinikin sunan "Dorzopt Plus". A mataki na asali miyagun ƙwayoyi da kuma Generic miyagun ƙwayoyi directed a rage intraocular matsa lamba priglaukome, wanda ke nufin cewa su ne m, kuma a cikin rashi na sayar da daya daga cikinsu za a iya sayi medicament samuwa a cikin kantin magani.

Wani analog na ido "Kosopt" droplets samar da Croatian "Yadran Galenski DD Laboratory" da ake kira "Dorzotimol". Kamar yadda wani ɓangare na wannan Generic ma ba a wani adadin dorzolamide hydrochloride 22.26 MG da 6,84 MG na timolol maleate, ya cigaba da, ƙarin aka gyara su daidaita. Domin magunguna shirye-shirye ne irin wannan, don haka yana iya zama Generic madadin dropwise "Kosopt". Umurnai na amfani analogs ake hada a cikin daya pharmaceutical kungiyar - "antiglaucoma kwayoyi." Alamomi, Hanyar da aikace-aikace, sashi, m halayen da kuma yawan abin sama (cututtuka) a duk uku magunguna dole dace ba. A manufacturer iya sa da kansa nuances a cikin shiriya a kan yin amfani da ido saukad.

A shirye-shiryen "Kosopt" (ido saukad) analogs za a iya ko dai a hade ko a monotherapies, a hada ko dai dorzolamide hydrochloride ko timolol maleate. A hali na biyu aiki sashi ne a hade analogues ne ba wani ɓangare na asali miyagun ƙwayoyi da kuma wannan ya haddasa bambance-bambance cikin tasiri, illa da interactions da sauran magunguna.

Monotherapy "timolol" a cikin nau'i na ido saukad da zuwa 0.25% da 0.5% - analogue "Kosopta" dangane timolol maleate samar India kamfanin "Gen Biotech Pvt. Co., Ltd. '. A cikin 1 ml na wakili ƙunshi timolol maleate (daidai Timolol) 2.5 MG da 5 MG.

Wani analogue ne Indian miyagun ƙwayoyi "Okumed" ido drop at biyu allurai - 0.25% da 0.5%. A manufacturer wannan yana nufin shi ne "Promed Aikawa Pvt. Co., Ltd. ", India. A cikin 1 ml bayani "Okumed" kamar yadda a cikin shirye-shiryen da "Timolol", yana dauke da aiki abu timolol maleate 2.5 da kuma 5 MG (daidai Timolol).

Jamus analogue eyedrops "Kosopt" a medicament "Arutimol" a biyu allurai - 0.25% da 0.5%, wanda aka samar da "Chauvin ankerfarm GmbH". A cikin abun da ke ciki saukad, kamar yadda a baya nufin abu ɗaya ta ƙunshi timolol maleate 2.5 MG da 5 MG (daidai Timolol).

A 2008, da Rasha kasuwar yana da irin wannan magani "Kosopt" analogue na Rasha "timolol-Akos" samar da pharmaceutical factory "kira na." An samar a cikin nau'i na m colorless ido saukad 0.25%. A abun da ke ciki na wannan wakili ne a hada 2.5 MG na timolol (a cikin nau'i na maleate).

A shirye-shiryen "Kosopt" bicomponent analogs raba na kowa aiki sashi na timolol maleate a wani adadin na 5 MG. Wadannan sun hada da digo "Azarga" co-samar da Belgium da kuma United Kingdom sha'anin "Alcon dakunan gwaje-gwaje (UK) Ltd.". A abun da ke ciki na wannan bayani ya hada da wani aiki sashi brinzolamide.

Wani irin wannan samfurin - "Fotil" samarwa "Santen AO" (Finland) a cikin abun da ke ciki qunshi droplets na pilocarpine hydrochloride at 20 da kuma 40 MG na timolol maleate da 5 MG.

Wani analogue "Kosopta" - monotherapy 'Trusopt' samar da "Merck Sharp & Dohme BV." A abun da ke ciki ƙunshi droplets dorzolamide hydrochloride a wani adadin na 2%.

Sharhi kan shirye-shiryen "Kosopt"

A amfani da antiglaucoma jamiái shi yiwuwa ba tare da wani na farko binciken da wani likita. Auna da intraocular matsa lamba kadai da mãsu haƙuri ne ba su iya, muna bukatar wani musamman na'urar, wanda aka yi amfani da wani ido likita. Inflated matsa lamba Manuniya a cikin masallãci ne dalilin da manufa "Kosopt" halitta (ido saukad). Reviews game da amfanin da miyagun ƙwayoyi, marasa lafiya bar mafi bambancin. Babban abu - don gano daga likita, da yadda za a amfani da magani da cewa ya amfana ko cũtar da hangen nesa. Da miyagun ƙwayoyi iya hana ci gaban glaucoma ko taimaka wajen rage ta bayyanar cututtuka.

A cikin shirye-shiryen "Kosopt" haƙuri sake dubawa ne korau. A ke so illa kamar itching, kona, redness na idanu, ne masababin an daina lura da ido saukad. A wannan yanayin, likitan ido sanya hade shirye-shirye, da abun da ke ciki na wanda akayi daban-daban hada dorzolamide hydrochloride ko timolol maleate. Zai yiwu rashin lafiyan halayen faruwa ne kawai a daya daga cikin "Kosopt" drop aka gyara, haƙuri shedu a kan effects na kowane miyagun ƙwayoyi jiyya zai taimaka wajen gyara.