Kwayoyin "Maxipime": umarnin don amfani, analogs da kuma sake dubawa

A samu na farko da kwayoyin (penicillin duk aka sani a yau) a tsakiyar karni na ashirin da ya nasara a magani. A lokacin yakin duniya na II, wannan magani ajiye rayukan dubban kare da Mahaifa, mahaifiyata.

Tun daga nan, Biochemistry, kuma Pharmaceutical masana'antu ne hanzari tasowa, da kuma yayi abokan ciniki mafi kuma mafi maganin rigakafi. Daya daga cikin mafi m da kuma amfani da ko'ina a fannoni daban daban na magani ne "Maxipime" wanda sake bitar gwada wannan kayan aiki a matsayin sosai, sosai tasiri ga daban-daban kwayan cututtuka.

Tsari da kuma abun da ke ciki

Babban aiki sashi na wannan miyagun ƙwayoyi ne tsefepimadigidrohlorida monohydrate. Thomas Production - yellowish foda whitish ya dafa for bayani ga m intramuscular ko igiyar jini gwamnati. A da dama dosages manufacturer yayi abokan ciniki da samfurin "Maxipime." A kwayoyin za a iya saya a cikin kwalabe kashi na 500 MG da kuma 1 g

A shirye abun da ke ciki na gwamnati iya adana a dakin da zazzabi for wata rana. A karkashin yanayi na firiji shiryayye rayuwa na tattalin bayani ya karu har zuwa 1 mako. A foda tsari da kuma a wani stoppered vial shiri iya adana for shekaru 3. Abubuwan da ake bukata - da yawan zafin jiki zuwa + 30 ° C da kuma kare su daga haske. Canza launi daga cikin bayani ba zai tasiri a ayyukan da miyagun ƙwayoyi.

pharmacological tasiri

"Maxipime 'umarnin don amfani wurin sa a matsayin antibacterial wakili cewa nasa ne da 4th tsara cephalosporins kungiyar. Manufa effects ne halakar da cell ganuwar da kwayoyin cuta damuwa. Da miyagun ƙwayoyi yana da m bakan da tasiri a dangane da wani fanni na gram-tabbatacce kuma gram-korau kwayoyin, an halin da juriya ga aminoglycosides da antibaktrialnym nufin uku-tsara cephalosporin kungiyar.

Domin "Maksipima" halayyar jure beta-lactamases da kuma aiki da wani babban yawan gram-tabbatacce kuma gram-korau aerobic (daki-daki jerin - a cikin umarnin don yin amfani). Amma magani ne ba aiki da metitsillinoustoychivym staphylococci, pneumococci penitsillinoustoychivye.

Bayan gabatarwar kwayoyin "Maxipime" (umurci manual hada da irin wannan bayanai) suna gaba daya tunawa. Therapeutically dacewa yawa daga cikin babban aiki bangaren ana gano a cikin fitsari, bile, Bronchial secretions, da prostate gland shine yake da peritoneal ruwa.

A rabin rayuwa ne kamar sa'o'i biyu. Don kwatanta, zamu iya cewa, misali, adult marasa lafiya da suke ga 9 kwanaki da igiyar jini samu 2 g da miyagun ƙwayoyi da tazarar lokaci tsakanin jiyya ga akalla 8 hours cefepime jari a cikin jiki ba a samu. A mafi girma adadin excreted a cikin fitsari (kiyaye up to 85% na asali samu haƙuri dosages kamar yadda canzawa cefepime).

alamomi

Antibacterial "Maxipime" umarnin don amfani da ake karfafa su gabatar da a iri daban-daban Pathology na dauke da kwayar cutar da kumburi yanayi. Good sakamakon da samu a lura da ƙananan numfashi fili cututtuka (ciwon huhu da kuma mashako ciki har da) da kuma urinary ducts (duka biyu ba rikitarwa, kuma rikitarwa ciki har da pyelonephritis). M kuzarin kawo cikas aka lura a lura da daban-daban dauke da kwayar cutar ciki-ciki raunuka (ba ban da biliary fili kamuwa da cuta da kuma peritonitis).

Har ila yau, "Maxipime" ne yadu amfani da kiwon lafiya kwararru da magani daga gynecological cututtuka, cututtuka na fata da kuma taushi nama raunuka, septicemia (sepsis). A lura da marasa lafiya da febrile neutropenia, "Maxipime" manual shawarar yadda empirical far.

Wani fannin na rinjayar da miyagun ƙwayoyi - kwayan meningitis a yara. Nan, wannan kwayoyin da aka ma da tabbatar.

A matsayin matakin rigakafi da miyagun ƙwayoyi da ake amfani da su hana cututtuka a cikin shakka daga ciki tiyata.

A general zamu iya cewa "Maxipime" halatta amfani a karkashin duk cututtuka, ci gaban da tsokani saukin kamuwa da kwayoyin cuta da kuma damuwa. Domin gane causative gabar da kuma sanin da (ko da) ji na ƙwarai to wannan kwayoyin kamata su yi gwaje-gwaje. Duk da haka, "Maxipime" rinjayar da m kewayon kwayan damuwa da kuma cewa shi a matsayin monotherapy za a iya dauka ko da kafin gano da pathogen. Idan akwai wani hadarin a gauraye kamuwa da cuta (aerobic-anaerobic), sa'an nan zuwa ga gwaje-gwaje a kan LURA na pathogenic kwayoyin cuta na iya fara jiyya "Maksipimom" a jummai da miyagun ƙwayoyi da shafi cikin anaerobes.

Dosing da dosing regimens

A sashi da kuma gwamnati form (w / w ko w / o) aka ƙaddara dangane da ji na ƙwarai daga kwayoyin cuta, da tsananin cutar jihar na haƙuri kuma kodan. Kuma da zan / Yã hanya mafi yawa ana fifita a lokuta inda da kamuwa da cuta shi ne wuya, kuma ya razana haƙuri ta rayuwa.

Mutane da lafiya da kodan da kuma yin la'akari fiye da 40 kg injections sanya a kan jinkiri na 12 hours a wani kashi wajabta ta your likita. Cuta na urinary fili m zuwa matsakaici mai tsanani, sauran cututtuka da ke faruwa a wannan tsanani, suna bi a dosages na 0.5-1 g, gudanar intravenously ko intramuscularly (as likita yanke shawarar). Don magance da tsanani cututtuka aikata intravenously gudanar a 2 g abu (periodicity ne guda - 12 hours). Domin nauyi sosai, kuma dauke da barazana ga rayuwar haƙuri da kamuwa da cuta da ake bukata sashi ne 2 g, amma periodicity - kowane 8 hours.

Kwayoyin "Maxipime" da ake amfani a mura kawai a kuma waɗannan lokuta inda ma kwayan alaka a kwarara daga wani kwayar cutar.

A cikin shakka daga m ayyukan (for 1 hour kafin) prophylactically intravenously kan wani 2 hour gubar g 'Maksipima "to, ku zuba ƙarin 500 MG na metronidazole. Lokaci guda gudanar biyu abubuwa da bai kamata ba.

A talakawan adadin da miyagun ƙwayoyi ga marasa lafiya da jiki nauyi bai kai 40 kg, a lura da urinary fili cututtuka (rikitarwa da kuma uncomplicated), taushi da nama da kuma fata (ba kange), na huhu kumburi da kuma empirical far na neutropenic zazzabi shi ne 50 MG da kilogram jiki nauyi. Injections sanya a kan jinkiri na 12 hours. A kwayan meningitis da neutropenic zazzabi guda 50 MG / kg gudanar bayar da shawarar jinkiri tsakanin jiyya, daidai da 8 hours.

Ga marasa lafiya fama da munanan a koda aiki, ake bukata don daidaita tabbatarwa kashi. Kwayoyin "Maxipime" bayanin da miyagun ƙwayoyi (sashi dangane da irin pathogen da kuma mai tsanani daga kamuwa da cuta za a tsince halartar likita) ya bada shawarar cewa na farko girma daga cikin miyagun ƙwayoyi dauki ne guda kamar yadda na mutane da lafiya da kodan, yayin da goyon bayan da sashi gyara dangane da dabi'u na creatine yarda.

Wadanda marasa lafiya da suke yi "Maxipime" da kuma jurewa hemodialysis, bada shawarar a karshen da hanya sake-shigar da sabon kashi na kwayoyin daidai da asali. Wannan wajibi ne, watau. K. Ga 3 hour na dialysis za a iya cire daga jiki zuwa 68% na jimlar adadin miyagun ƙwayoyi "Maxipime" (mai amfani ƙunshi wannan bayani).

Contraindications "Meksipima"

Duk da musamman fadi da kewayon antibacterial sakamakon wannan miyagun ƙwayoyi, shi ba shi da wani dogon jerin contraindications. "Maxipime" umurci manual haramta mutane tare da mutum hypersensitivity zuwa cefepime da L-arginine. Har ila yau, shi ne unacceptable bai wa marasa lafiya da halayen da nan da nan hypersensitivity zuwa penicillins, wasu beta-lactam jamiái, maganin rigakafi kamar cephalosporin.

Hankalinsa zuwa jiharsa na kiwon lafiya a lokacin jiyya "Maksipimom" dole ne mu bi mata masu ciki da masu shayarwa da uwaye, mutanen da fama da cututtuka na narkewa kamar fili, musamman a cikin irin cututtuka kamar ulcerative ko kwayoyin-hade colitis, yankin enteritis.

Kamar yadda na da tasiri a kan haihuwa aiki, dole ne a ce cewa a cikin gwajinsu a kan dabbobi ne ba illa a kan uwa da tayin da aka gano. Duk da haka, da kyau-sarrafawa nazarin daga cikin sakamako a kan mace ta jiki da aka za'ayi. Saboda haka, mata masu juna biyu m "Maxipime" kawai a karkashin likita dubawa. A adam nono madara miyagun ƙwayoyi da aka saki a sosai kananan yawa, amma ba daraja da hadarin. A lokacin da lactation tafii da magani tare da taka tsantsan.

Bugu da kari, kwayoyin "Maxipime" manual ya bayar da shawarar yin amfani da da tsananin kulawa ga wadanda suka sha wahala mai tsanani na kullum na koda gazawar. Nazarin ya nuna cewa a cikin marasa lafiya da na kullum na koda gazawar da ya karu rabin-rai na abu daga jiki. A lokaci guda, mutane da cutar hanta, ko cystic fibrosis ba ji da wani pharmacokinetic canje-canje saboda sha da kuma tukar tumbi da cefepime.

Side effects, da suka wuce haddi na halatta kashi

A general zamu iya cewa "Maxipime" da kyau jure, da kuma abin da ya faru na m events ba high. Dukkan lokuta ya ruwaito mafi yawa shi game da aiki na narkewa kamar fili cuta (dyspepsia, zawo, maƙarƙashiya, tashin zuciya da amai), da kuma hypersensitivity halayen (rash, itching, zazzabi).

Bugu da kari, da bayanai samuwa a kan wannan miyagun ƙwayoyi a matsayin kwayoyin "Maxipime" - a bayanin irin shirye-shiryen, umarnin gare ta amfani, - shaidar da yiwuwar dauki a kan wani ɓangare na zuciya da jijiyoyin jini tsarin a cikin nau'i na tachycardia (zuciya palpitations) da kuma ciwon kirji. numfashi tsarin iya bayyana kanta a ciwon makogwaro, shortness na numfashi da kuma tari. A mafi m martani daga CNS zai zama rashin barci, zai yiwu ciwon kai, dizziness, tashin hankali, rudani, paresthesia. Daga cikin wasu bayyananen za mu iya magana game da gajiya, vaginitis, sweating, zafi, ciwon baya, na gefe edema. Har ila yau, a matsayin gefen sakamakon likita kwararru magana game da wani yiwu canji a dakin gwaje-gwaje sigogi.

Amma impermissibly samun allurai na rigakafi "Maxipime" umurci manual sanar da game da tasiri na hemodialysis a irin haka.

Abin da ya kamata ka kula da?

Weight na daban-daban m yanayi na iya ci gaba a lokacin tsawon lokacin da wajabta maganin rigakafi "Maxipime." Yadda za a amfani da shi a wannan harka? Idan bango na "Maksipima" ɓullo da pseudomembranous colitis tare da shafe tsawon zawo, a daina shan shi a duk da gudanar vancomycin ko metronidazole.

Idan haƙuri shan wahala daga mai tsanani a hade hanta da koda gazawar, kiwon lafiya kamata gudanar gudana monitoring da miyagun ƙwayoyi taro a jini jini da kuma, dangane da sigogi, daidaita da sashi.

Idan kwayoyin da ya kasance akwai na dogon lokaci, shi ne muhimmanci a kai a kai saka idanu da abun da ke ciki na gefe jini da kuma aikin Manuniya na koda da hanta.

A lokuta inda wani haƙuri daga m cututtuka mayar da hankali lura meningeal watsa (yaduwar pathogens, duka a cikin hearth, kuma a ko'ina cikin jiki), akwai tuhuma da meningitis ko wani ganewar asali an riga an shigar, shi wajibi ne don ki magani "Maksipimom" da kuma sanya kakoe- ko madadin antibacterial wakili tare da tabbatar da inganci ga ganewar asali.

Akwai yiwuwar a gano wani m dauki ga Coombs 'test, ƙarya-tabbatacce - a gaban glucose a fitsari.

"Maxipime" na mura da kuma sanyi (Ina nufin a kwayar cututtuka) ba zai zama mai tasiri.

Hulda da sauran abubuwa

Idan haƙuri da ake sa a yi maka "Maxipime" layi daya aikace-aikace na wasu kwayoyi ya zama karkashin likita dubawa. Wannan kwayoyin ne ba pharmaceutically jituwa tare da sauran antimicrobial magunguna da kuma heparin.

Tubular mugunya cefepime bude ma rage a lokacin da a hade tare da diuretics, aminoglycosides da polymyxin B. A wannan karuwa jummai PM maida hankali "Maksiprima" a cikin jini magani zai kara har da ci gaban nephrotoxicity nefronekroza. Bugu da kari, ƙara da rabin-rai.

Hada "Maksiprima" tare da NSAIDs (ba steroidal anti-kumburi kwayoyi) rage gudu da tukar tumbi da cephalosporins na jiki da kuma zai iya sa zub da jini.

A amfani a hade tare da sauran bactericidal maganin rigakafi (aminoglycosides) zai haifar a cikin bayyanuwar Matsayi tare da bacteriostatic - abotar.

magunguna analogues

Medicaments analogs aka zaba bisa kan kasa da kasa nonproprietary sunan (INN), a nan tare da babban aiki sashi (for "Maksipima" wannan shi ne cefepime). Mafi mashahuri takwarorinsu antibacterial wakili "Maxipime" comments daga masana ake magana a kai irin wannan kwayoyi a matsayin "Cefepime-Alpes", "Cefepime", "Movizar", "maxicef" "Cefepime bakarare."

Wannan ba wani cikakken jerin, kuma kamar yadda sunan "Cefepime", a nan, in Baya ga sama, har yanzu akwai "Cefepime-vial", "Cefepime-Agio" "Cefepime-Dzhodas" "Cefepime-Alkema," "Cefepime Hydrochloride ".

Har ila yau a cikin daban-daban na kwayan cututtuka masu samar rubũta kwayoyi zuwa sama "Ladef", "Efipim", "Kefsepim", "Tsefomaks", "chainsWe".

Game da magunguna takwarorina, da suka iya ba ko da yaushe zama kamar tasiri a matsayin lasisi miyagun ƙwayoyi.

Ra'ayi da marasa lafiya da kuma ma'aikatan kiwon lafiya

Tun da miyagun ƙwayoyi yana da fadi da kewayon aikace-aikace a cikin wani m iri-iri da ake dasu cututtuka, sa'an nan da ra'ayi daga cikin "Maksipime" akwai wani m shugabanci, kuma korau. Mafi yawan mutane sama maganin rigakafi, sun gamsu da sakamakon. Inganta kiwon lafiya, ko da a cikin tsanani siffofin kwayan cututtuka faru kwanaki 2-3 daga farkon far. A cewar ma'aikatan kiwon lafiya, da miyagun ƙwayoyi ma ya tabbatar da kansa a cikin wani iri-iri na asibiti yanayi. Kuma da kudin na mai magani ne ba haka ba sosai high (akwai mai rahusa magunguna, amma a lokaci guda, akwai muhimmanci mafi tsada fiye da "Maxipime").

Duk da haka, akwai ba haka kaffa ra'ayi game da miyagun ƙwayoyi. Mafi yawa korau comments a cikin wadanda marasa lafiya da suke yi bayyana kansu a cikin hanya na lura illa. Bugu da kari, da mummunan ra'ayin da aka bayyana ta a raba rukuni na mutane suka riƙi maganin rigakafi "Maxipime" for colds. Ko da yake a wannan harka sakamakon shi ne, kamar yadda aka zata. Duk wani sanyi ne a kwayar halitta, da kuma "Maxipime" - a germicide, da manufa na wanda dogara ne a kan tasirin da lalata jikin tantanin na kwayoyin.

Saya magani za a iya ciwon takardar sayen magani daga likita. Kuma da gaskiya da haka: likita da musamman ilimi da kwarewa, saboda haka zabi antimicrobial da lissafi da m tasiri kashi, cewa duk da kasada na illa an rage girmanta da kuma tabbatacce sakamakon a jiki za a maximized.