Paraneoplastic ciwo a matsayin nuni daga malignancy

A cewar gwaji Oncology, ƙari ne kawai cuta, abin da ke faruwa daidai a dukkan mambobi na dabba mulkin. A etiology da ciwon daji, kazalika da ta pathogenesis ba tukuna cikakken gane da masana kimiyya, amma a wannan lokacin akwai 4 babban theories:

1. kwayar. A cewar shi, carcinogenic kaddarorin da wasu ƙwayoyin cuta: Epstein-Barr cutar, herpes cutar, papilloma cutar, da sauransu.

2. Physico-sinadaran. Babban rawa a ƙari cin yi sinadaran Carcinogens (3,4-benzpyrene, metabolites da kuma amino acid din da Tir UKU, aflatoxins et al.), Ionizing radiation.

3. dizontogeneticheskie: neoplastic matakai tashi daga m Alamomi kyallen takarda a lokacin da amfrayo lokaci.

4. Mixed - musanta monoetiologichnost ƙari.

ƙari bayyananen

Symptomatology oncological matakai a cikin jiki suna kasu gida da kuma janar ãyõyi. Local siffofin ne kai tsaye shaidar da ƙari, amma sau da yawa ya bayyana daga baya general, suna hade da marurai m sakamako a kan manufa gabobin ko malfunctioning tawayar rigakafi da tsarin. Irin wannan cututtuka ana hade a da ake kira paraneoplastic syndromes. Suna halin rashin sadarwa tare da na gida rinjayar da ƙari jure far, da cin kawai idan akwai ciwon daji da kuma bace a lokacin da m magani. Wannan damar domin da bambanci ganewar asali PNS tare da m tsari cututtuka.

A pathogenesis na PNS

Tun paraneoplastic ciwo tasowa tushen aiki da ƙari, ko da metastasis, pathogenesis kowane ciwo hade da wani na rayuwa cuta ko wani rigakafi da tsarin reactivity. Saboda haka, mafi marurai ne wani nau'i ne na "tarkuna" domin gina jiki (bitamin, glucose, amino acid, lipids), saboda abin da tasowa degeneration na da yawa tsokoki da kuma janar cachexia. Har ila yau, a gaban m antigens a atypical Kwayoyin da take kaiwa zuwa giciye-al'ada rigakafi martani saboda lalace ko maligniziruyutsya wanda al'ada Kwayoyin. A ƙari da cewa ya tashi a kan tushen da endocrine Kwayoyin nuna ƙarin ji ba gani. A wannan yanayin, paraneoplastic ciwo zai faru dangane da m rage ji na ƙwarai to hormones rabe da worsening rayuwa cuta.

wasu PNS

A mafi m marurai ne siffofin marurai na endocrine nama. A wannan dangane akwai wani endocrine paraneoplastic ciwo. Ya bayyana ne wani ƙara taro na hormone a cikin jini, kuma ta tsare ko bayan resection na ta samar da gland da kuma rage mugunya kan kau da ƙari.

Articular ciwo bayyana a matsayin hypertrophic osteoarthropathy, kartsinolidnoy arthropathies, gouty amosanin gabbai, polyarthritis. Wannan paraneoplastic ciwo yawanci Earsbe ganewar asali da marurai da kuma inganta harkokin ko da a baya ganewa na malignancy.

Hematological da neurological syndromes da mafi tsanani hanya da sauri mutuwa. Bayyana canza gwada yawa da kuma gwajin kwari abun da ke ciki na jini da kuma neuropathy, abu don komowar kwayoyin canje-canje a cikin kyallen takarda.