Acetone Halitosis

Wasu waje jiki canji kamar kurji, fata discoloration, musamman sputum, baki wari, ya dade da aka dauke da likitoci a cikin ganewar asali da wasu cututtuka. Acetone da m wari da fitsari, fata, ko baki iya zama alamun daban-daban cututtuka: ciwon sukari na farko ko na biyu da irin, atsetonemichesky ciwo, zuciya matsaloli, cututtuka da kuma sauran alamu na rashin lafiya. Wari na acetone numfashin yaro ko adult aka bayyana da fitowan da wani hadadden tsari, shi yawanci ba ya dogara ne a kan tsufa. Wannan shi ne saboda da karuwa a jinin mutum ketone jikinsu: acetoacetate (H3C-CO-CH2-COOH ) da kuma β-hydroxybutyrate (H3C-CHOH-CH2-COOH ).

Rayuwa jihar wadda aka sa ta high yawa daga ketone gawarwakin kafa a lokacin bazuwar daga m acid, kira ketoacidosis. Yana da wani pathological yanayin tafiyar matakai na rayuwa ne saboda gaskiyar cewa jiki shi ne iya mayalwaci tsara samar da ketones, keto acid tara a sakamakon canje-canje da jini PH. A matsanancin ketoacidosis iya zama m. Wannan rayuwa da jihar ne ya fi kowa a ciwon sukari na farko da irin.

Tsawo amfani da barasa ya auku giya ketoacidosis, yayin da kuma bayyana acetone numfashin wari saboda da abun ciki na acetone a cikin numfashi, wanda yake shi ne byproduct kwatsam lalata da acetoacetic acid. An sau da yawa aka bayyana a matsayin wani ruwa turare goge bãyani.

A high yawa na glucose a cikin jini (hyperglycemia), ya sa ta hanyar rashin insulin (na farko da irin ciwon sukari) ko Kwayoyin rashin iyawa to yakamata amsa insulin (na biyu da irin ciwon sukari) take kaiwa zuwa wani m karuwa da acidity na jini. A lafiya mutane, wannan yawanci ba ya faru saboda pancreas samar da isasshen insulin, ko da Kwayoyin yadda ya kamata amsa da generated isa wani hormone da pancreas. A sakamakon haka, glucose shiga cikin sel (su ne ba jin yunwa), ta maida hankali a cikin jini ba girma, kuma babu wani martani da karuwa a cikin taro na jini ketone jikinsu. Saboda haka m mutane (fama da ciwon sukari ba) acetone numfashin wari fakowa ba.

A m marasa lafiya, ketoacidosis yana tare da hyperglycemia (high jini sugar magani) da kuma dehydration (dehydration). Oversupply na glucose zai iya kai ga uncontrolled samar da ketone jikuna (ta hanyar m acid metabolism), wani yanayin a cikin abin da akwai wari da acetone numfashi a wani yaro ko balagagge. A sakamakon haka ne a koda obalodi, urinary glucose bayyana (a sabon abu da ake kira glucosuria), wanda a wani m kwayoyin da aka resorbed da koda baya a cikin jini. Contact tare da fitsari glucose saboda ta dagagge maida hankali a cikin jini taimaka wajen ruwa hasãra. M ketoacidosis ne yiwuwar rai-barazanar mutane da ciwon sukari. Wannan na faruwa yafi a marasa lafiya tare da irin ciwon sukari, amma zai iya, a cikin wani yanayi, da faruwa a mutane da Type II ciwon sukari.

A giya ketoacidosis barasa sa dehydration da kuma tarewa mataki na farko a gluconeogenesis - rayuwa hanya kai ga ƙarni na glucose daga wadanda ba carbohydrate carbon substrates kamar lactate, glycerol da sauransu. Wannan shi ne daya daga biyu manyan hanyoyin tsarin amfani da mutane da wasu dabbobi da jiki don kula da jini glucose matakan, wanda taimaka wajen kauce wa fadowa ma low (a yanayin da ake kira da qarancin ruwa da). Sauran wajen rike jini glucose matakin ne glycogenolysis - sarrafa glycogen (carbohydrate ajiye). Idan jiki ba ya da isasshen yawa na glucose ga ikon Kwayoyin, halitta rikicin makamashi, a sakamakon da mayar da martani daga m acid metabolism da kuma ketone gawarwakin kafa bayyana acetone numfashin wari.

Soft acidosis iya haifar daga tsawo azumi ko ketogenic abun da ake ci (a rage cin abinci a hada abinci dauke da high yawan furotin da kuma kitse, low carbohydrates) wanda a magani da yafi amfani da su bi unmanageable epilepsy a yara, cututtukan zuciya, na kullum gajiya ciwo da kuma sauran jihohi. Low-carbohydrate abun da ake ci wajabta nauyi iko da kuma lura da kiba, kuma iyakance ci daga carbohydrates. A can farko na irin wannan abinci da rasa glycogen, game da wani rana. Sa'an nan, jiki yana amfani da ga madadin makamashi kafofin (fats da kuma sunadarai), wanda aka kafa a lokacin da lalata da ketone jikinsu, da kuma bayyana acetone numfashin wari.