Neuroleptic m ciwo ya kira ...

Neuroleptic m ciwo ne mai rare da fraught tare da sakamakon ga rai na rashin lafiya ya sa ta ci na psychotropic kwayoyi, musamman neuroleptics na zuwa kungiyoyin na phenothiazines, thioxanthenes da butirofenonov. NMS iya tsokana da yin amfani da kayan aikin kamar amphetamine, "Amoksalin" "Fluoxetine", "desipramine", "phenelzine" hodar Iblis ko "metoclopramide".

dalilai

Yiwuwar samun dalilai kafa neuroleptic ciwo iya zama:

• gwamnati na kwayoyi tsawo daukan hotuna.
• vysokopotentnyh yin amfani da kudi.
• da ake ji da NMS mallakan kwayoyi tare da anticholinergic kwayoyi.
• antidepressants.
• iska zazzabi.
• Electroconvulsive magani da kuma high zafi.

Ƙarin tsanani cututtuka zai iya sa dalilai kai tsaye ya yiwuwa ga physiological alheri daga mãsu haƙuri. Don wadanda sun hada da:

• dehydration.
• psychomotor ruri.
• shan barasa.
• shafi tunanin mutum retardation .
• da zubar lokaci.
• intercurrent cututtuka.
• rashin baƙin ƙarfe.
• gajiya,.
• traumatic kwakwalwa rauni.
• thyroid tabarbarewa.

Jihar incoherence, tsofaffi, wani tunanin tashin hankali, da ɗa namiji - duk da wannan kuma ƙara da zuwa neuroleptic m ciwo. ZNR cututtuka iya zama quite daban-daban - daga qananan to ri.

Easy iri-iri na

Neuroleptic m ciwo halin da wadannan alamomi: zazzabi yakan to subfebrile faruwa somatovegetativnye kananan laifinsu (jini bugun jini a cikin 150 / 90-110 / 70 mm Hg, tachycardia - har zuwa 100 lashe da minti ..) Kazalika munanan a dakin gwaje-gwaje data (ƙãra ESR zuwa 18-30 mm / h, da low yawan lymphocytes - daga 15 zuwa 19%). Babu cuta da homeostasis da hemodynamic girma. Psychopathological jihar da aka kafa oneiric-catatonic ko affective delusional harin.

A talakawan digiri na

Gaskiyar cewa wani mutum ba shi da lafiya neuroleptic m ciwo matsakaiciya, nuna wadannan alamu:

• nuna somatovegetativnye cuta (fuka da tachycardia zuwa 120 lashe minti daya);
• zazzabi (38-39 digiri).
• gagarumin canje-canje a cikin dakin gwaje-gwaje data (ESR qara zuwa 35-50 mm / h, kuma leukocytosis - up 10J109 / l, da yawa daga leukocytes rage-rage wa 10-15%).
• ya karu creatine phosphokinase matakan da tranzaminaza jini.
• A fadin saukar hypokalemia da hypovolemia.

Psychopathological cuta halin da irin ji amentivnopodobnoy da oneiric digiri. Catatonic bayyanar cututtuka bayyana immobility negativism, ta ƙara mita (da yamma) lokuta na hangula nervousness, motsi da kuma jawabin stereotype.

hadaddun tsari

A kan bango na hyperthermia iya faruwa neuroleptic m ciwo. Alamun mafi tsanani riga, wato:

• Littafi somatovegetativnye kasawa (. dyspnea zuwa 30 breaths da 1 minti daya, tachycardia isa 120-140 lashe minti daya);
• kara ruwa da kuma electrolyte cuta.
• ya karu hemodynamic disturbances.

A mafi girma canji halaye gano a cikin dakin gwaje-gwaje Figures. ESR qara zuwa 40-70 mm / h Leucocytes - up 12J109 / l, rage yawan lymphocytes zuwa 3-10%, muhimmanci ƙara mataki na creatine, alanine da asparagine transaminase a cikin jini. Clouding da hankali zai iya isa up comatose, kuma soporous amential matakai. Mãyen, negativism, m hangula, lethargy, tare da wani karu a tsoka sautin kuma, a musamman tsanani lokuta, da kuma cikakken immobility da areflexia - duk neuroleptic m ciwo.

magani

Farkon ganewa na cuta shi ne babban batu. Gaskiyar cewa wani mutum ya kasance majinyaci neuroleptic m ciwo iya nuna murdede tashin hankali, tachycardia, zazzabi, hauhawar jini, sweating gano bayan samun neuroleptics, dysphagia.

Abu na farko da za ka yi wani likita, don haka shi soke neuroleptics da sauran neurotoxic kwayoyi. Har ila yau bukatar goyon bayan hanyoyin kawo saukar da zafin jiki da kuma yin sama da rashin ruwa. Electrolyte imbalances dole ne a fitar da mulki. Ake bukata don gudanar da wani m saka idanu na numfashi da harshen damo, da aiki da abin da za a iya karya sake lokacin da kafa tsanani murdede rigidity da gazawan su expectorate Bronchial mugunya.

Kana bukatar ka saka idanu a hankali koda aiki. Duk da haka, babu wani tabbaci cewa osmotic rabuwa accelerates murmurewa daga NMS, kawai shi zai iya taimaka da tallafi na koda aiki. An sau da yawa ake bukata, don samar da wani far a wani wuri inganta magani.

magani

Bi da neuroleptic m ciwo magunguna ne kyawawa a halaye da wuya. A saboda wannan dalili, tsoka relaxants ( "Dantrolene") ko dopamine agonists ( "Amantadine" da "bromocriptine"). Mace-mace da aka rage a cikin yin amfani da da iri na kwayoyi. Allurai bambanta da yardar kaina, amma ga "Bromocriptine" dabaru da aka bayyana a cikin kafofin a adadi daga 2.5 zuwa 5 MG sau 3 a rana baki.

Dopamine agonists, musamman in ya fi girma rabo, mai yiwuwa fararwa psychosis ko amai, da kuma shi ne iya muhimmanci worsen Jihar kiwon lafiya na haƙuri neuroleptic m ciwo. Direct addashin tsoka relaxant amfani da allurai na 10 MG / kg. Manufar ta yin amfani - rage tsoka rigidity, kazalika da metabolism na kwarangwal tsoka, da karuwa wanda shi ne jera alhakin hyperthermia. "Dantrolene" bambanta hepatotoxicity iya tsokana hepatitis har ma da mutuwa saboda hanta gazawar. Kuma a sa'an nan za a ba dalili don ci gaba da yi wa neuroleptic m ciwo.

NMS ma an shafe ta da wata hade da dopamine da kuma "dantrolene" agonists. Anticholinergic kwayoyi suna yadu amfani da magani daga pseudoparkinsonism lalacewa ta hanyar antipsychotic kwayoyi, ba su samar da gagarumin sakamakon, haka ma, zai iya ci gaba da rushe thermoregulation.

Akwai wani update a kan tasiri na "carbamazepine" cewa da yawa marasa lafiya nuna wani m weakening na NSA shaidarsa. Duk da haka, akwai wani abin dogara da bayanai a kan tasiri na amfani da benzodiazepines domin lura da wannan ciwo. Duk da haka, a lokacin da yanayin inganta, wadannan kwayoyi na iya zama da amfani a rage hangula a marasa lafiya da ciwon neuroleptic m ciwo.

hyperthermia

A cutar za a iya samu kamar sau daya a kowace 100 tysyach maganin sa barci amfani depolarizing tsoka relaxants ( "Miorelaksina", "ditilina" da "listenon"), kazalika da inhalation anesthetics daga halogen hydrocarbons ( "methoxyflurane", "Ftorogana" da "Halothane") . Hyperthermia bayyana a cikin marasa lafiya da high laulayi wadannan kwayoyi, wanda dangantaka tare da kasawa na alli metabolism a tsoka taro. A sakamakon haka ne kowa yana da tsoka twitching, da kuma wani lokacin tsoka cuta, wadda aka kafa a sakamakon babban adadin zafi, yanayin jiki instantaneously kai 42 digiri. Neuroleptic m Syndrome matarwa a 20-30% na lokuta.

motar asibiti

Bayan ganewa na azumi-girma hyperthermia bukatar dakatar da shan aka ambata a sama kwayoyi. Saboda m kwayoyi, kada ku sa cuta, za a iya gano barbiturates "pancuronium", "Tubocurarine" da kuma nitrous oxide. Kamar su ya kamata a yi amfani da, idan ya cancanta, da tsawo na maganin sa barci kula.

Saboda yiwuwar samuwar na ramin zuciya fibrillation aka rajista prophylactic "Phenobarbital" da "Procainamide" warkewa dosages. Shi ne kuma dole a shirya sanyaya hanya, ajiye a kan manyan jini ganga tare da ruwan sanyi ko kankara. Yana bukatar nan da nan normalize numfashi iska, allurar sodium hydrogencarbonate / a (400 ml na 3% bayani). A m lokuta, shi shawarar aiwatar da farfado da. Arin - wannan shi ne abu na farko da ka yi idan kamu neuroleptic m ciwo.

Outlook

Yanzu a cikin tarihi na NSA ne ko da yaushe qara da alama na irin wannan jiha da na biyu ya kwarara da kuma wuya hanya da rinjaye malaise. Bugu da ƙari, cuta kunno kai a wannan ciwo suna kusan ba bypassed kwakwalwa tsarin ba tare da wata alama, samar da wadanda ko wasu neurological cuta. To, abin da yake neuroleptic m ciwo? Yana yake akwai wata cuta da cewa muhimmanci impairs rayuwar mutum, kuma ko da na iya kai ga mutuwa.